Botanical species · safety record

Butea monosperma

The EFSA Compendium of Botanicals holds 2 constituent measurements and 7 adverse-effect records for Butea monosperma. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Butea monosperma (Lam.) Taub.

2Constituent measurements
7Safety records
4Cited sources
7Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 7 licensed products naming Butea monosperma as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Source material stated

  • Branch bark
  • Flower
  • Seed(s)
  • Stem bark

What the records describe

Constituents measured

  • Cajanin1
  • Isoformononetin1

Plant parts

  • Seed6
  • Stem2
  • stalk2
  • Roots and other underground parts1

Preparations

  • Powder4
  • Solvent extraction3

Effect types

  • Endocrine3
  • Digestive1
  • Nephrotoxicity1
  • Other toxicities1
  • Reproductive1

Target tissues

  • Uterus3
  • Digestive1
  • Testes1
  • Urogenital: kidneys1
  • Urogenital: prostrate1

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
CajaninStem / stalkSolvent extractionUnspecifiedResolve DOI
IsoformononetinStem / stalkSolvent extractionUnspecifiedResolve DOI

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

EffectTarget tissuePlant partPreparationTest organismTest typeSource
DigestiveDigestiveSeedPowderRat (as animal)SubchronicResolve DOI
EndocrineUterusSeedRat (as animal)Reproduction toxicityResolve DOI
EndocrineUterusSeedRat (as animal)Reproduction toxicityResolve DOI
NephrotoxicityUrogenital: kidneysSeedPowderRat (as animal)SubchronicResolve DOI
Other toxicitiesUrogenital: prostrateSeedPowderRat (as animal)SubchronicResolve DOI
ReproductiveTestesSeedPowderRat (as animal)SubchronicResolve DOI
EndocrineUterusRoots and other underground partsSolvent extractionHouse mouse (as animal)Reproduction toxicityNo resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Sharm, S.K., Rai, G., Vasudeva, N. Anti-fertility investigation of Butea monosperma (Lam.) kuntze root in female albino mice. Research journal of medicinal plant, 2012, vol. 6, no. 3, p. 260-266.
  2. Donga, Shilpa., Shukla, Vinay J., Ravishankar, B., Ashok, B K., Mishtry, I U. Chronic toxicity study of Butea monosperma (Linn.) Kuntze seeds in albino rats.. Ayu, 2011, vol. 32, no. 1, p. 120-5. DOI
  3. Kumar, Dinesh., Kumar, Ajay., Prakash, Om. Potential antifertility agents from plants: A comprehensive review. JOURNAL OF ETHNOPHARMACOLOGY, 2012, vol. 140, no. 1, p. 1-32. DOI
  4. Bhargavan, Biju., Gautam, Abnish Kumar., Singh, Divya., Kumar, Amit., Chaurasia, Sumit., Tyagi, Abdul Malik., Yadav, Dinesh Kumar., Mishra, Jay Sharan., Singh, Amar Bahadur., Sanyal, Sabyasachi., Goel, Atul., Maurya, Rakesh., Chattopadhyay, Naibedya. Methoxylated Isoflavones, Cajanin and Isoformononetin, Have Non-Estrogenic Bone Forming Effect Via Differential Mitogen Activated Protein Kinase (MAPK) Signaling. JOURNAL OF CELLULAR BIOCHEMISTRY, 2009, vol. 108, no. 2, p. 388-399. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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