Botanical species · safety record
Butea monosperma
The EFSA Compendium of Botanicals holds 2 constituent measurements and 7 adverse-effect records for Butea monosperma. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Butea monosperma (Lam.) Taub.
Regulatory presence
Health Canada's Licensed Natural Health Products Database holds 7 licensed products naming Butea monosperma as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.
Source material stated
What the records describe
Constituents measured
- Cajanin1
- Isoformononetin1
Plant parts
- Seed6
- Stem2
- stalk2
- Roots and other underground parts1
Preparations
- Powder4
- Solvent extraction3
Effect types
- Endocrine3
- Digestive1
- Nephrotoxicity1
- Other toxicities1
- Reproductive1
Target tissues
- Uterus3
- Digestive1
- Testes1
- Urogenital: kidneys1
- Urogenital: prostrate1
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Cajanin | Stem / stalk | Solvent extraction | — | Unspecified | Resolve DOI |
| Isoformononetin | Stem / stalk | Solvent extraction | — | Unspecified | Resolve DOI |
Recorded adverse effects
Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.
| Effect | Target tissue | Plant part | Preparation | Test organism | Test type | Source |
|---|---|---|---|---|---|---|
| Digestive | Digestive | Seed | Powder | Rat (as animal) | Subchronic | Resolve DOI |
| Endocrine | Uterus | Seed | — | Rat (as animal) | Reproduction toxicity | Resolve DOI |
| Endocrine | Uterus | Seed | — | Rat (as animal) | Reproduction toxicity | Resolve DOI |
| Nephrotoxicity | Urogenital: kidneys | Seed | Powder | Rat (as animal) | Subchronic | Resolve DOI |
| Other toxicities | Urogenital: prostrate | Seed | Powder | Rat (as animal) | Subchronic | Resolve DOI |
| Reproductive | Testes | Seed | Powder | Rat (as animal) | Subchronic | Resolve DOI |
| Endocrine | Uterus | Roots and other underground parts | Solvent extraction | House mouse (as animal) | Reproduction toxicity | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Sharm, S.K., Rai, G., Vasudeva, N. Anti-fertility investigation of Butea monosperma (Lam.) kuntze root in female albino mice. Research journal of medicinal plant, 2012, vol. 6, no. 3, p. 260-266.
- Donga, Shilpa., Shukla, Vinay J., Ravishankar, B., Ashok, B K., Mishtry, I U. Chronic toxicity study of Butea monosperma (Linn.) Kuntze seeds in albino rats.. Ayu, 2011, vol. 32, no. 1, p. 120-5. DOI
- Kumar, Dinesh., Kumar, Ajay., Prakash, Om. Potential antifertility agents from plants: A comprehensive review. JOURNAL OF ETHNOPHARMACOLOGY, 2012, vol. 140, no. 1, p. 1-32. DOI
- Bhargavan, Biju., Gautam, Abnish Kumar., Singh, Divya., Kumar, Amit., Chaurasia, Sumit., Tyagi, Abdul Malik., Yadav, Dinesh Kumar., Mishra, Jay Sharan., Singh, Amar Bahadur., Sanyal, Sabyasachi., Goel, Atul., Maurya, Rakesh., Chattopadhyay, Naibedya. Methoxylated Isoflavones, Cajanin and Isoformononetin, Have Non-Estrogenic Bone Forming Effect Via Differential Mitogen Activated Protein Kinase (MAPK) Signaling. JOURNAL OF CELLULAR BIOCHEMISTRY, 2009, vol. 108, no. 2, p. 388-399. DOI
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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