Botanical species · safety record

Butea superba

The EFSA Compendium of Botanicals holds 5 constituent measurements, 3 adverse-effect records and 1 genotoxicity assay for Butea superba. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Butea superba Roxb.

5Constituent measurements

4Safety records

8Cited sources

10Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 10 licensed products naming Butea superba as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Source material stated

Root
Tuber

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Isoflavones	Roots and other underground parts used as staple food	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Biochanin-a	Roots and other underground parts	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Butin	Flower	Solvent extraction	—	Unspecified	No resolvable identifier
Isoflavones	Roots and other underground parts	Solvent extraction	—	Unspecified	No resolvable identifier
Isoflavones	Roots and other underground parts	Solvent extraction	—	HPLC-UV	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Endocrine	Testes	Roots and other underground parts used as staple food	Solvent extraction	Rat (as animal)	Subchronic	Resolve DOI
Hemopoietic	Cardiovascular / haematological	Roots and other underground parts used as staple food	Solvent extraction	Rat (as animal)	Subchronic	Resolve DOI
Endocrine	—	Roots and other underground parts	Solvent extraction	—	Other	No resolvable identifier

Genotoxicity testing

Outcomes of genotoxicity assays as recorded in the source. A negative assay is a result under those test conditions, not a clearance.

Outcome	Endpoint	Test	Tested organism	Metabolic activation	Source
Positive	DNA damage and/or repair	Mammalian erythrocyte micronucleus test	Rat (as animal)	—	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Cherdshewasart, Wichai., Bhuntaku, Papong., Panriansaen, Rattana., Dahlan, Winai., Malaivijitnond, Suchinda. Androgen disruption and toxicity tests of Butea superba Roxb., a traditional herb used for treatment of erectile dysfunction, in male rats . Maturitas, 2008, vol. 60, no. 2, p. 131-137. DOI
BRADBURY, RB., WHITE, DE. ESTROGENS AND RELATED SUBSTANCES IN PLANTS. Vitamins and hormones-advances in research and applications, 1954, vol. 12, p. 207-233.
Pongpanparadon, A., Aritajat, S., Saenphet, K. The toxicology of Butea superba, Roxb.. The southeast asian journal of tropical medicine and public health, 2002, vol. 33 Suppl 3, p. 155-8.
Eumkeb, G., Naknarong, W., Sirichaiwetchakoon, K. The effects of red kwao krue (Butea superba Roxb.) extract on sperm quality and testosterone level in mice. Thai j. pharm. sci., 2013, vol. 38, no. SUPPL., p. 120-123.
Ma, K., Ishikawa, T., Seki, H., Furihata, K., Ueki, H., Narimatsu, S., Higuchi, Y., Chaichantipyuth, C. Isolation of new isoflavonolignans, butesuperins A and B, from a thai miracle herb, Butea superba . Heterocycles, 2005, vol. 65, no. 4, p. 893-900.
Manosroi, A., Manosroi, J., Palaniswamy, UR., Gardner, ZE., Craker, LE. Determination of bioactive compounds in roots of different ages Pueraria mirifica, Airy Shaw Suvatabhandhu and Butea superba, Roxb. from various locations in Thailand . Wocmap iii: traditional medicine and nutraceuticals, 2005, no. 680, p. 93-96.
Ngamrojanavanich, Nattaya., Loontaisong, Aimon., Pengpreecha, Somchai., Cherdshewasart, Wichai., Pornpakakul, Surachai., Pudhom, Khanitha., Roengsumran, Sophon., Petsom, Amorn. Cytotoxic constituents from Butea superba Roxb.. Journal of ethnopharmacology, 2007, vol. 109, no. 2, p. 354-358. DOI
Rao, V. Subba., Seshadri, T. R. Chemical composition of the flowers of Butea superba. Journal of scientific & industrial research, 1949, vol. 8B, p. 178-9.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature