Botanical species · safety record

Camellia sinensis

The EFSA Compendium of Botanicals holds 13 constituent measurements and 2 adverse-effect records for Camellia sinensis. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Camellia sinensis (L.) Kuntze

13Constituent measurements

2Safety records

6Cited sources

4,083Licensed products (Canada)

Also recorded as

Thea sinensis L.

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 4,083 licensed products naming Camellia sinensis as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Dry
Extract Type TBA
Fresh
decoction

Source material stated

Aloe vera - Latex
Buds
Camellia sinensis
Camellia sinensis (Green tea) leaf
Camellia sinensis - Leaf extract
Camellia sinensis - leaf
Dried leaf
Flower

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Caffeine	Flower	Solvent extraction	3.1 Percent	Colorimetry, Spectroscopy (Spectrometry) and Photometry	Resolve DOI
Caffeine	Leaves	Solvent extraction	≤ 0.13 Percent	Chromatographic tests	Resolve DOI
Epicatechin-3-gallate	Leaves	Solvent extraction	≤ 0.91 Percent	Chromatographic tests	Resolve DOI
Epigallocatechin	Leaves	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Epigallocatechin gallate	Leaves	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Gallic acid	Leaves	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Gallocatechin-3-gallate	Leaves	Solvent extraction	≤ 1.6 Percent	Chromatographic tests	Resolve DOI
Saponins	Flower	Solvent extraction	0.9 Percent	Colorimetry, Spectroscopy (Spectrometry) and Photometry	Resolve DOI
Caffeine	Leaves	Solvent extraction	6.9 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Epicatechin-3-gallate	Leaves	Solvent extraction	2.8 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Epigallocatechin	Leaves	Solvent extraction	10.4 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Epigallocatechin gallate	Leaves	Solvent extraction	10.9 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Theophylline	Leaves	—	—	Unspecified	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Systemic	—	Leaves	Solvent extraction	Dog (as animal)	Short-term toxicity	Resolve DOI
Systemic	—	Leaves	Solvent extraction	Dog (as animal)	Short-term toxicity	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Wu, Kuei-Meng., Yao, Jiaqin., Boring, Daniel. Green Tea Extract-Induced Lethal Toxicity in Fasted but Not in Nonfasted Dogs . International journal of toxicology, 2011, vol. 30, no. 1, p. 19-20. DOI
Isbrucker, RA., Bausch, J., Edwards, JA., Wolz, E. Safety studies on epigallocatechin gallate (EGCG) preparations. Part 1: Genotoxicity . Food and chemical toxicology, 2006, vol. 44, no. 5, p. 626-635. DOI
Li, Bo., Jin, Yuxia., Xu, Yi., Wu, Yuanyuan., Xu, Jiying., Tu, Youying. Safety evaluation of tea (Camellia sinensis (L.) O. Kuntze) flower extract: Assessment of mutagenicity, and acute and subchronic toxicity in rats . Journal of ethnopharmacology, 2011, vol. 133, no. 2, p. 583-590. DOI
Nikaidou, S., Ishizuka, M., Maeda, Y., Hara, Y., Kazusaka, A., Fujita, S. Effect of components of green tea extracts, caffeine and catechins on hepatic drug metabolizing enzyme activities and mutagenic transformation of carcinogens . Japanese journal of veterinary research, 2005, vol. 52, no. 4, p. 185-192.
BuAbbas, A., Copeland, E., Clifford, MN., Walker, R., Ioannides, C. Fractionation of green tea extracts: Correlation of antimutagenic effect with flavanol content . Journal of the science of food and agriculture, 1997, vol. 75, no. 4, p. 453-462. DOI
No Author and Editor data available. NTP Toxicology and Carcinogenesis Studies of Theophylline (CAS No. 58-55-9) in F344/N Rats and B6C3F1 Mice (Feed and Gavage Studies). National toxicology program technical report series, 1998, vol. 473, p. 1-326.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

Continue

Independent literature