Botanical species · safety record

Cannabis indica

The EFSA Compendium of Botanicals holds 34 constituent measurements and 7 adverse-effect records for Cannabis indica. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Cannabis indica Lam.

34Constituent measurements

7Safety records

8Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Cannabidiol	Fruit unspecified	Solvent extraction	≥ 26.6 Percent	GC-MS	Resolve DOI
Cannabidiol	Fruit unspecified	Solvent extraction	≤ 54.48 Percent	GC-MS	Resolve DOI
Cannabigerol	Fruit unspecified	Solvent extraction	≥ 0.11 Percent	GC-MS	Resolve DOI
Cannabigerol	Fruit unspecified	Solvent extraction	≤ 0.7 Percent	GC-MS	Resolve DOI
Cannabinoids	Fruit unspecified	Solvent extraction	≥ 0.11 Percent	GC-MS	Resolve DOI
Cannabinoids	Fruit unspecified	Solvent extraction	≤ 4.51 Percent	GC-MS	Resolve DOI
Cannabinoids	Fruit unspecified	Solvent extraction	≤ 0.7 Percent	GC-MS	Resolve DOI
Cannabinoids	Fruit unspecified	Solvent extraction	≥ 1.29 Percent	GC-MS	Resolve DOI
Cannabinoids	Aerial part of plants	Super-critical gas extraction	—	—	Resolve DOI
Cannabinoids	Aerial part of plants	Super-critical gas extraction	26 Percent	—	Resolve DOI
Cannabinol	Fruit unspecified	Solvent extraction	≤ 0.82 Percent	GC-MS	Resolve DOI
Cannabinol	Fruit unspecified	Solvent extraction	≥ 15.07 Percent	GC-MS	Resolve DOI
Cannabinol	Fruit unspecified	Solvent extraction	≤ 67.4 Percent	GC-MS	Resolve DOI
Cannabinol	Fruit unspecified	Solvent extraction	≥ 0.12 Percent	GC-MS	Resolve DOI
Carvone	Aerial part of plants	Solvent extraction	≤ 5.13 Percent	GC-MS	Resolve DOI
Carvone	Aerial part of plants	Solvent extraction	≥ 2.11 Percent	GC-MS	Resolve DOI
Delta-9-tetrahydrocannabinol	Fruit unspecified	Solvent extraction	23.84 Percent	GC-MS	Resolve DOI
Myrcene	Aerial part of plants	Solvent extraction	≥ 1.062 Percent	GC-MS	Resolve DOI
Myrcene	Aerial part of plants	Solvent extraction	≤ 1.81 Percent	GC-MS	Resolve DOI
Tetrahydrocannabivarin	Fruit unspecified	Solvent extraction	≤ 2.03 Percent	GC-MS	Resolve DOI
Tetrahydrocannabivarin	Fruit unspecified	Solvent extraction	≥ 0.03 Percent	GC-MS	Resolve DOI
Cannabidiol	Aerial part of plants	Solvent extraction	≤ 54.48 Percent	GC-MS	No resolvable identifier
Cannabidiol	Aerial part of plants	—	—	—	No resolvable identifier
Cannabidiol	Aerial part of plants	Solvent extraction	≥ 26.6 Percent	GC-MS	No resolvable identifier
Cannabigerol	Aerial part of plants	—	—	—	No resolvable identifier
Cannabinoids	Aerial part of plants	—	—	—	No resolvable identifier
Cannabinoids	Aerial part of plants	Solvent extraction	≥ 0.03 Percent	GC-MS	No resolvable identifier
Cannabinoids	Aerial part of plants	Solvent extraction	≤ 5.14 Percent	GC-MS	No resolvable identifier
Cannabinol	Aerial part of plants	Solvent extraction	≥ 15.07 Percent	GC-MS	No resolvable identifier
Cannabinol	Aerial part of plants	Solvent extraction	≤ 67.4 Percent	GC-MS	No resolvable identifier
Cannabinol	Aerial part of plants	—	—	—	No resolvable identifier
Delta-9-tetrahydrocannabinol	Aerial part of plants	Solvent extraction	≤ 23.84 Percent	GC-MS	No resolvable identifier
Delta-9-tetrahydrocannabinol	Aerial part of plants	Solvent extraction	≥ 1.03 Percent	GC-MS	No resolvable identifier
Delta-9-tetrahydrocannabinol	Aerial part of plants	—	1 Percent	—	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Neurotoxicity	Neurologic: central nervous system	Unspecified	—	Rat (as animal)	Chronic/long term toxicity	Resolve DOI
Neurotoxicity	Neurologic	—	—	Human (as organism)	Case report	Resolve DOI
Neurotoxicity	Neurologic	—	—	—	Acute toxicity	Resolve DOI
Reproductive	Urogenital	Unspecified	—	Rat (as animal)	Chronic/long term toxicity	Resolve DOI
Systemic	Glandular	Aerial part of plants	Super-critical gas extraction	Rat (as animal)	Subchronic	Resolve DOI
Systemic	—	Aerial part of plants	Super-critical gas extraction	Rat (as animal)	Short-term toxicity	Resolve DOI
Systemic	Testes	Aerial part of plants	Super-critical gas extraction	Rat (as animal)	Short-term toxicity	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Qureshi, M.N., Kanwal, F., Siddique, M., Inayat-ur-Rahman., Akram, M. Estimation of biologically active cannabinoids in Cannabis indica by Gas Chromatography-mass Spectrometry (GC-MS). World applied sciences journal, 2012, vol. 19, no. 7, p. 918-923. DOI
Marselos, Marios., Karamanakos, Petros. Mutagenicity, developmental toxicity and carcinogenicity of cannabis. Addiction biology, 1999, vol. 4, no. 1, p. 5-12.
Chan, PC., Sills, RC., Braun, AG., Haseman, JK., Bucher, JR. Toxicity and carcinogenicity of Delta(9)-tetrahydrocannabinol in Fischer rats and B6C3F1 mice. Fundamental and applied toxicology, 1996, vol. 30, no. 1, p. 109-117. DOI
Qureshi, Muhammad Nasimullah., Kanwal, Farina., Siddique, Muhammad., Inayat-ur-Rahman., Akram, Muhammad. Estimation of biologically active Cannabinoids in Cannabis indica by gas chromatography-mass spectrometry (GC-MS). World applied sciences journal, 2012, vol. 19, no. 7, p. 918-923.
Marx, Tennille K., Reddeman, Robin., Clewell, Amy E., Endres, John R., Beres, Erzsebet., Vertesi, Adel., Glavits, Robert., Hirka, Gabor., Szakonyine, Ilona Pasics. An Assessment of the Genotoxicity and Subchronic Toxicity of a Supercritical Fluid Extract of the Aerial Parts of Hemp. Journal of toxicology, 2018. DOI
Naz, Saima., Hanif, Muhammad Asif., Bhatti, Haq Nawaz., Ansari, Tariq Mahmood. Impact of Supercritical Fluid Extraction and Traditional Distillation on the Isolation of Aromatic Compounds from Cannabis indica and Cannabis sativa . Journal of essential oil bearing plants, 2017, vol. 20, no. 1, p. 175-184. DOI
MOHAN, H., SOOD, G C. CONJUGATE DEVIATION OF THE EYES AFTER CANNABIS INDICA INTOXICATION.. The british journal of ophthalmology, 1964, vol. 48, p. 160-1. DOI
Favretto, Donata., Montisci, Massimo., Snenghi, Rossella., Andreazza, AC., Scola, G. Forensic Toxicology. Toxicology studies - cells, drugs and environment, 2015, p. 85-100. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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