Botanical species · safety record

Cardiospermum halicacabum

The EFSA Compendium of Botanicals holds 9 constituent measurements and 2 adverse-effect records for Cardiospermum halicacabum. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Cardiospermum halicacabum L.

9Constituent measurements

2Safety records

4Cited sources

20Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 20 licensed products naming Cardiospermum halicacabum as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Source material stated

Aerial flowering part
Aerial part of flowering plant
Flowering aerial part(s)
Flowering aerial parts
Fresh aerial part collected at flowering time
Fresh aerial parts of flowering plant
Fresh aerial parts of the flowering plant
Fresh flowering aerial parts

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Alkaloids	Leaves	Solvent extraction	—	Phytochemical screening	Resolve DOI
Calcium oxalate	Leaves	Drying (dehydration)	—	Microscopic detection	Resolve DOI
Saponins	Leaves	Solvent extraction	—	Phytochemical screening	Resolve DOI
Saponins	Roots and other underground parts	Solvent extraction	—	—	Resolve DOI
Tannins	Roots and other underground parts	Solvent extraction	—	—	Resolve DOI
Tannins	Leaves	Solvent extraction	—	Phytochemical screening	Resolve DOI
3,4-dihydroxybenzaldehyde	Unspecified	—	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	No resolvable identifier
3,4-dihydroxybenzoic acid	Unspecified	—	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	No resolvable identifier
Calycosin	Unspecified	—	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Systemic	—	Roots and other underground parts	Solvent extraction	House mouse (as animal)	Acute toxicity	Resolve DOI
Reproductive	Uterus	Live plants	Solvent extraction	Rat (as animal)	Reproduction toxicity	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Chen, Jun., Wei, Jian-Hua., Cai, Shao-Fang., Miao, Wei-Sheng., Pan, Li-Wei. Study on chemical constituents of Cardiospermum halicacabum .. Zhong yao cai = zhongyaocai = journal of chinese medicinal materials, 2013, vol. 36, no. 2, p. 228-30.
Suhas, S.N., Vilas, D.V. Pharmacognostic evaluation of dried leaf powder of Cardiospermum halicacabum Linn. and dried seed hull powder of Hydnocarpus pentandra (Buch.-Ham.) Oken. International journal of research in ayurveda and pharmacy, 2014, vol. 5, no. 4, p. 502-507. DOI
Dhanwad, R., Purohit, M.G., Patil, S., Patil, S.B., Satyanarayan, N.D. Antiimplantation activity of ethanolic extract of cardiospermum halicacabum linn. (sapindaceae) in albino rats. Indian drugs, 2005, vol. 42, no. 11, p. 726-730.
Dhayabaran, Daniel., Florance, Jeyaseeli., Krsihnadas, Nandakumar., Indumathi., Muralidhar. Anticonvulsant activity of alcoholic root extract of Cardiospermum halicacabum . Revista brasileira de farmacognosia-brazilian journal of pharmacognosy, 2012, vol. 22, no. 3, p. 623-629. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature