Botanical species · safety record

Carissa carandas

The EFSA Compendium of Botanicals holds 11 constituent measurements and 1 adverse-effect record for Carissa carandas. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Carissa carandas L.

11Constituent measurements

1Safety records

6Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Pentacyclic triterpenic derivatives	Leaves	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Pentacyclic triterpenic derivatives	Leaves	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Alkaloids	Fruit unspecified	—	1.96 Gram/100 gram	Gravimetric tests	No resolvable identifier
Alkaloids	Roots and other underground parts	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Digitoxigenin	—	—	—	—	No resolvable identifier
Lignans	Stem / stalk	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Myrcene	—	—	—	—	No resolvable identifier
Saponins	Roots and other underground parts	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Saponins	Fruit unspecified	—	1.03 Gram/100 gram	Gravimetric tests	No resolvable identifier
Tannins	Roots and other underground parts	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Tannins	Fruit unspecified	—	1.02 Gram/100 gram	Colorimetry, Spectroscopy (Spectrometry) and Photometry	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Digestive	Digestive	Fruit unspecified	Solvent extraction	—	In vitro	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Gupta, Priti., Bhatnagar, Ira., Kim, Se-Kwon., Verma, Ajay Kumar., Sharma, Anubhuti. In-vitro cancer cell cytotoxicity and alpha amylase inhibition effect of seven tropical fruit residues . Asian pacific journal of tropical biomedicine, 2014, vol. 4, no. Suppl. 2, p. S665-S671.
Mishra, C.K., Shrivastava, B., Sasmal, D. Pharmacognostical standarization and phytochemical identification of fruit and root of Carissa carandas Linn. International Journal of Pharmacy and Pharmaceutical Sciences, 2013, vol. 5, no. SUPPL 3, p. 347-350.
Rastogi, R. C., Rastogi, Ram P., Dhar, M. L. Carissa carandas. II. Polar glycosides. Indian journal of chemistry, 1967, p. 215-216. .[abstract].
Wangteeraprasert, Ruchira., Likhitwitayawuid, Kittisak. Lignans and a Sesquiterpene Glucoside from Carissa carandas Stem. HELVETICA CHIMICA ACTA, 2009, vol. 92, no. 6, p. 1217-1223.
Zaki, A. Y., El-Tohamy, S. F., El-Fattah, S. A. Study of lipid content and volatile oil of the different organs of Carissa carandas Lin. and Carissa grandiflora Dc. growing in Egypt. Egyptian journal of pharmaceutical sciences, 1983, p. 127-141. .[abstract].
Siddiqui, BS., Ghani, U., Ali, ST., Usmani, SB., Begum, S. Triterpenoidal constituents of the leaves of Carissa carandas. NATURAL PRODUCT RESEARCH, 2003, vol. 17, no. 3, p. 153-158. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature