Botanical species · safety record
Carthamus tinctorius
The EFSA Compendium of Botanicals holds 3 constituent measurements, 2 adverse-effect records and 3 genotoxicity assays for Carthamus tinctorius. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Carthamus tinctorius L.
Regulatory presence
Health Canada's Licensed Natural Health Products Database holds 605 licensed products naming Carthamus tinctorius as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.
Extract types on licence
Source material stated
What the records describe
Constituents measured
- 4-hydroxyacetophenone1
- 4-hydroxybenzaldehyde1
- 4-hydroxybenzoic acid1
Plant parts
- Live plants3
- Flower2
Preparations
- Solvent extraction5
Effect types
- Reproductive2
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| 4-hydroxyacetophenone | Live plants | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | No resolvable identifier |
| 4-hydroxybenzaldehyde | Live plants | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | No resolvable identifier |
| 4-hydroxybenzoic acid | Live plants | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | No resolvable identifier |
Recorded adverse effects
Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.
| Effect | Target tissue | Plant part | Preparation | Test organism | Test type | Source |
|---|---|---|---|---|---|---|
| Reproductive | — | Flower | Solvent extraction | House mouse (as animal) | Reproduction toxicity | Resolve DOI |
| Reproductive | — | Flower | Solvent extraction | House mouse (as animal) | Reproduction toxicity | Resolve DOI |
Genotoxicity testing
Outcomes of genotoxicity assays as recorded in the source. A negative assay is a result under those test conditions, not a clearance.
| Outcome | Endpoint | Test | Tested organism | Metabolic activation | Source |
|---|---|---|---|---|---|
| Positive | gene mutation | bacterial reverse mutation assay | Salmonella typhimurium (as organism) | Without | Resolve DOI |
| Positive | DNA damage and/or repair | Mammalian erythrocyte micronucleus test | House mouse (as animal) | — | No resolvable identifier |
| Positive | chromosome aberration | chromosome aberration assay | House mouse (as animal) | — | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- YIN, XJ., LIU, DX., WANG, HC., ZHOU, Y. A STUDY ON THE MUTAGENICITY OF 102 RAW PHARMACEUTICALS USED IN CHINESE TRADITIONAL MEDICINE. MUTATION RESEARCH, 1991, vol. 260, no. 1, p. 73-82.
- Nobakht, M., Fattahi, M., Hoormand, M., Milanian, I., Rahbar, N., Mahmoudian, M. A study on the teratogenic and cytotoxic effects of safflower extract. Journal of ethnopharmacology, 2000, vol. 73, no. 3, p. 453-459. DOI
- Abudayyak, Mahmoud., Ozdemir Nath, Ebru., Ozhan, Gul. Toxic potentials of ten herbs commonly used for aphrodisiac effect in Turkey. TURKISH JOURNAL OF MEDICAL SCIENCES, 2015, vol. 45, no. 3, p. 496-506. DOI
- Li, Xiao-Feng., Hu, Xiao-Ru., Dai, Zhong., Zhang, Yan., Liang, Hong., Lin, Rui-Chao. Study on chemical constituents of Carthamus tinctorius .. Zhong yao cai = zhongyaocai = journal of chinese medicinal materials, 2012, vol. 35, no. 10, p. 1616-9.
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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