Botanical species · safety record

Carum carvi

The EFSA Compendium of Botanicals holds 12 constituent measurements and 1 genotoxicity assay for Carum carvi. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Carum carvi L.

12Constituent measurements

1Safety records

7Cited sources

153Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 153 licensed products naming Carum carvi as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Dry
Extract Type TBA

Source material stated

Carum carvi - seed
Dried ripe fruit
Fruit
Fruit(s)
Grain(s)
Graine
New material
Seed

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Carvone	Seed	Essential oil	53.6 Percent	Gaschromatography (GC)	Resolve DOI
Carvone	Fruit unspecified	Essential oil	≤ 95.9 Percent	Gaschromatography (GC)	Resolve DOI
Carvone	Fruit unspecified	Essential oil	≥ 44.5 Percent	Gaschromatography (GC)	Resolve DOI
Carvone	Fruit unspecified	Essential oil	63.2 Percent	GC-MS	Resolve DOI
Carvone	Seed	Solvent extraction	≤ 0.05 Percent	Gelpermeation, High Performance Thin Layer Chromatography (HPTLC)	Resolve DOI
Carvone	Seed	Solvent extraction	≥ 0.019 Percent	Gelpermeation, High Performance Thin Layer Chromatography (HPTLC)	Resolve DOI
Myristicin	Seed	Solvent extraction	≤ 0.033 Percent	Gelpermeation, High Performance Thin Layer Chromatography (HPTLC)	Resolve DOI
Myristicin	Seed	Solvent extraction	≥ 0.016 Percent	Gelpermeation, High Performance Thin Layer Chromatography (HPTLC)	Resolve DOI
Umbelliferone	Seed	Solvent extraction	≤ 0.0041 Percent	Gelpermeation, High Performance Thin Layer Chromatography (HPTLC)	Resolve DOI
Umbelliferone	Seed	Solvent extraction	≥ 0.0017 Percent	Gelpermeation, High Performance Thin Layer Chromatography (HPTLC)	Resolve DOI
Carvone	Seed	Essential oil	81.5 Percent	GC-MS	No resolvable identifier
Carvone	Seed	Super-critical gas extraction	49.3 Percent	GC-MS	No resolvable identifier

Genotoxicity testing

Outcomes of genotoxicity assays as recorded in the source. A negative assay is a result under those test conditions, not a clearance.

Outcome	Endpoint	Test	Tested organism	Metabolic activation	Source
Positive	—	bacterial reverse mutation assay	Salmonella typhimurium (as organism)	No data	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Dhalwal, Kamlesh., Shinde, Vaibhav M., Mahadik, Kakasaheb R. Efficient and sensitive method for quantitative determination and validation of umbelliferone, carvone and myristicin in Anethum graveolens and Carum carvi seed . Chromatographia, 2008, vol. 67, no. 1-2, p. 163-167. DOI
Mahmoud, I., Alkofahi, A., Abdelaziz, A. Mutagenic and toxic activities of several spices and some jordanian medicinal plants. Pharmaceutical biology, 1992, vol. 30, no. 2, p. 81-85. DOI
Park, Il-Kwon., Kim, Junheo N., Lee, Yeon-Suk., Lee, Sang-Gil., Ahn, Young-Joon., Shin, Sang-Chul. Toxicity of plant essential oils and their components against Lycoriella ingenua (Diptera : Sciaridae) . Journal of economic entomology, 2008, vol. 101, no. 1, p. 139-144. DOI
Chowdhury, A. R. GC-MS studies on essential oil from Carum carvi L. raised in Kumaon. Journal of essential oil-bearing plants, 2002, vol. 5, no. 3, p. 158-161.
Raal, Ain., Arak, Elmar., Orav, Anne. The content and composition of the essential oil Found in Carum carvi L. commercial fruits obtained from different countries . Journal of essential oil research, 2012, vol. 24, no. 1, p. 53-59. DOI
Synowiec, A., Kalemba, D., Drozdek, E., Bocianowski, J. Phytotoxic potential of essential oils from temperate climate plants against the germination of selected weeds and crops . Journal of pest science, 2017, vol. 90, no. 1, p. 407-419. DOI
Semenov, V. V., Rusak, V. V., Chartov, E. M., Zaretskii, M. I., Konyushkin, L. D., Firgang, S. I., Chizhov, A. O., Elkin, V. V., Latin, N. N., Bonashek, V. M., . Polyalkoxybenzenes from plant raw materials. 1. Isolation of polyalkoxybenzenes from CO2 extracts of Umbelliferae plant seeds. Russian chemical bulletin, 2007, vol. 56, no. 12, p. 2448-2455.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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