Botanical species · safety record
Casimiroa edulis
The EFSA Compendium of Botanicals holds 36 constituent measurements for Casimiroa edulis. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Casimiroa edulis La Llave
Regulatory presence
No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.
What the records describe
Constituents measured
- Quinoline alkaloids8
- Phellopterin5
- Heraclenin4
- Isopimpinellin4
- Coumarins2
- Imperatorin2
- Psoralen2
- Bergapten1
- Casimiroedine1
- Furanocoumarins1
Plant parts
- Seed15
- Leaves11
- Bark7
- Aerial part of plants1
- Fruit unspecified1
- Unspecified1
Preparations
- Solvent extraction35
- Essential oil1
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Casimiroedine | Seed | Solvent extraction | — | Phytochemical screening | Resolve DOI |
| Heraclenin | Seed | Solvent extraction | ≥ 0.13 Percent | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Heraclenin | Leaves | Solvent extraction | ≤ 0.76 Percent | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Heraclenin | Leaves | Solvent extraction | ≥ 0.2 Percent | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Heraclenin | Seed | Solvent extraction | ≤ 1.96 Percent | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Heraclenol | Leaves | Solvent extraction | 0.08 Percent | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Herniarin | Seed | Solvent extraction | — | Standard Chromatographic tests (paper- thin layer- and column chromatography) | Resolve DOI |
| Imperatorin | Leaves | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Imperatorin | Seed | Solvent extraction | 0.39 Percent | HPLC-DAD | Resolve DOI |
| Isopimpinellin | Leaves | Solvent extraction | ≤ 0.14 Percent | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Isopimpinellin | Leaves | Solvent extraction | ≥ 0.09 Percent | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Isopimpinellin | Seed | Solvent extraction | — | Standard Chromatographic tests (paper- thin layer- and column chromatography) | Resolve DOI |
| Phellopterin | Seed | Solvent extraction | ≤ 2.11 Percent | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Phellopterin | Seed | Solvent extraction | ≥ 0.13 Percent | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Phellopterin | Leaves | Solvent extraction | ≤ 0.48 Percent | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Phellopterin | Seed | Solvent extraction | — | Standard Chromatographic tests (paper- thin layer- and column chromatography) | Resolve DOI |
| Phellopterin | Leaves | Solvent extraction | ≥ 0.08 Percent | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Psoralen | Leaves | Solvent extraction | — | LC-MS | Resolve DOI |
| Psoralen | Seed | Solvent extraction | — | Standard Chromatographic tests (paper- thin layer- and column chromatography) | Resolve DOI |
| Quinoline alkaloids | Fruit unspecified | Solvent extraction | — | Standard Chromatographic tests (paper- thin layer- and column chromatography) | Resolve DOI |
| Quinoline alkaloids | Seed | Solvent extraction | — | Phytochemical screening | Resolve DOI |
| Quinoline alkaloids | Seed | Solvent extraction | — | Standard Chromatographic tests (paper- thin layer- and column chromatography) | Resolve DOI |
| Umbelliferone | Leaves | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Xanthotoxol | Leaves | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Bergapten | Bark | Solvent extraction | 0.0035 Percent | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
| Coumarins | Aerial part of plants | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | No resolvable identifier |
| Coumarins | Unspecified | Essential oil | — | Nuclear Magnetic Resonance (NMR) | No resolvable identifier |
| Furanocoumarins | Seed | Solvent extraction | 0.0112 Percent | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
| Isopimpinellin | Bark | Solvent extraction | 0.0122 Percent | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
| Quinoline alkaloids | Seed | Solvent extraction | 0.0012 Percent | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
| Quinoline alkaloids | Bark | Solvent extraction | ≥ 0.0026 Percent | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
| Quinoline alkaloids | Bark | Solvent extraction | ≤ 0.0052 Percent | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
| Quinoline alkaloids | Bark | Solvent extraction | ≤ 0.0052 Percent | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
| Quinoline alkaloids | Bark | Solvent extraction | ≥ 6e-04 Percent | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
| Scopoletin | Bark | Solvent extraction | 0.0015 Percent | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
| Synephrine | Seed | Solvent extraction | — | IR and Raman Spectroscopy | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Froldi, Guglielmina., Bertin, Riccardo., Secchi, Enrico., Zagotto, Giuseppe., Martinez-Vazquez, Mariano., Garcia-Argaez, Aida. Vasorelaxation by extracts of Casimiroa spp. in rat resistance vessels and pharmacological study of cellular mechanisms . Journal of ethnopharmacology, 2011, vol. 134, no. 3, p. 637-643. DOI
- Nagai, Hiroyuki., Tanaka, Toshiyuki., Goto, Tsuyoshi., Kusudo, Tatsuya., Takahashi, Nobuyuki., Kawada, Teruo. Phenolic compounds from leaves of Casimiroa edulis showed adipogenesis activity . Bioscience biotechnology and biochemistry, 2014, vol. 78, no. 2, p. 296-300. DOI
- Bertin, R., Chen, Z., Martinez-Vazquez, M., Garcia-Argaez, A., Froldia, G. Vasodilation and radical-scavenging activity of imperatorin and selected coumarinic and flavonoid compounds from genus Casimiroa . Phytomedicine, 2014, vol. 21, no. 5, p. 586-594. DOI
- Awaad, Amani S., Maitland, Derek J., Moneir, Samar M. New alkaloids from Casimiroa edulis fruits and their pharmacological activity . Chemistry of natural compounds, 2007, vol. 43, no. 5, p. 576-580. DOI
- Awaad, Amani S., Al-Jaber, Nabilah A., Soliman, Gamal A., Al-Outhman, Mounerah R., Zain, Mohamed E., Moses, John E., El-Meligy, Reham M. New Biological Activities of Casimiroa edulis Leaf Extract and Isolated Compounds . Phytotherapy research, 2012, vol. 26, no. 3, p. 452-457. DOI
- Ito, A., Shamon, LA., Yu, BY., Mata-Greenwood, E., Lee, SK., van Breemen, RB., Mehta, RG., Farnsworth, NR., Fong, HHS., Pezzuto, JM., Kinghorn, AD. Antimutagenic constituents of Casimiroa edulis with potential cancer chemopreventive activity . Journal of agricultural and food chemistry, 1998, vol. 46, no. 9, p. 3509-3516. DOI
- Kincl, F.A., Romo, J., Rosenkranz, G., Sondhkimer, F. The constituents of casimiroa edulis llave et lex. Part I. The seed.*. Journal of the chemical society (resumed), 1956, p. 4150-4157.
- Iriarte, J., Kincl, F.A., Rosenkranz, G., Sondheimer, F. The constituents of casimiroa edulis llave et lex. Part II.* The bark. Journal of the chemical society (resumed), 1956, p. 4158-4160.
- Power, F.B., Callan, T. CCXXVI. - The constituents of the seeds of Casimiroa edulis. Journal of the chemical society, transactions, 1911, vol. 99, p. 1993-2010. DOI
- Magos, GA., Vidrio, H., Reynolds, WF., Enriquez, RG. Pharmacology of Casimiroa edulis IV. Hypotensive effects of compounds isolated from methanolic extracts in rats and guinea pigs . Journal of ethnopharmacology, 1999, vol. 64, no. 1, p. 35-44.
- Garcia-Argaez, Aida N., Gonzalez-Lugo, Nadia M., Marquez, Carmen., Martinez-Vazquez, Mariano. Coumarins present in species of the genus Casimiroa. Revista de la sociedad quimica de mexico, 2003, vol. 47, no. 2, p. 151-154.
- Awaad, A. S., Soliman, G. A. Essential oil, coumarins, and flavonoids of Casimiroa edulis leaves growing in Egypt and their biological activities. Egyptian journal of biomedical sciences, 2004, vol. 15, p. 42-58.
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
Continue
Europe PMC
Every record indexed for this species, resolvable and re-runnable.
All speciesSubstance index
Search and browse every species this world holds under source and hash.
Before anything elseSafety Centre
Interactions, contraindications and the escalation boundary this world does not cross.
In its own termsTraditions
How the living traditions approach preparation, use and context.