Botanical species · safety record

Casimiroa edulis

The EFSA Compendium of Botanicals holds 36 constituent measurements for Casimiroa edulis. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Casimiroa edulis La Llave

36Constituent measurements
0Safety records
12Cited sources
0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

  • Quinoline alkaloids8
  • Phellopterin5
  • Heraclenin4
  • Isopimpinellin4
  • Coumarins2
  • Imperatorin2
  • Psoralen2
  • Bergapten1
  • Casimiroedine1
  • Furanocoumarins1

Plant parts

  • Seed15
  • Leaves11
  • Bark7
  • Aerial part of plants1
  • Fruit unspecified1
  • Unspecified1

Preparations

  • Solvent extraction35
  • Essential oil1

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
CasimiroedineSeedSolvent extractionPhytochemical screeningResolve DOI
HeracleninSeedSolvent extraction≥ 0.13 PercentHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
HeracleninLeavesSolvent extraction≤ 0.76 PercentHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
HeracleninLeavesSolvent extraction≥ 0.2 PercentHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
HeracleninSeedSolvent extraction≤ 1.96 PercentHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
HeraclenolLeavesSolvent extraction0.08 PercentHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
HerniarinSeedSolvent extractionStandard Chromatographic tests (paper- thin layer- and column chromatography)Resolve DOI
ImperatorinLeavesSolvent extractionNuclear Magnetic Resonance (NMR)Resolve DOI
ImperatorinSeedSolvent extraction0.39 PercentHPLC-DADResolve DOI
IsopimpinellinLeavesSolvent extraction≤ 0.14 PercentHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
IsopimpinellinLeavesSolvent extraction≥ 0.09 PercentHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
IsopimpinellinSeedSolvent extractionStandard Chromatographic tests (paper- thin layer- and column chromatography)Resolve DOI
PhellopterinSeedSolvent extraction≤ 2.11 PercentHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
PhellopterinSeedSolvent extraction≥ 0.13 PercentHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
PhellopterinLeavesSolvent extraction≤ 0.48 PercentHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
PhellopterinSeedSolvent extractionStandard Chromatographic tests (paper- thin layer- and column chromatography)Resolve DOI
PhellopterinLeavesSolvent extraction≥ 0.08 PercentHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
PsoralenLeavesSolvent extractionLC-MSResolve DOI
PsoralenSeedSolvent extractionStandard Chromatographic tests (paper- thin layer- and column chromatography)Resolve DOI
Quinoline alkaloidsFruit unspecifiedSolvent extractionStandard Chromatographic tests (paper- thin layer- and column chromatography)Resolve DOI
Quinoline alkaloidsSeedSolvent extractionPhytochemical screeningResolve DOI
Quinoline alkaloidsSeedSolvent extractionStandard Chromatographic tests (paper- thin layer- and column chromatography)Resolve DOI
UmbelliferoneLeavesSolvent extractionNuclear Magnetic Resonance (NMR)Resolve DOI
XanthotoxolLeavesSolvent extractionNuclear Magnetic Resonance (NMR)Resolve DOI
BergaptenBarkSolvent extraction0.0035 PercentStandard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier
CoumarinsAerial part of plantsSolvent extractionHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)No resolvable identifier
CoumarinsUnspecifiedEssential oilNuclear Magnetic Resonance (NMR)No resolvable identifier
FuranocoumarinsSeedSolvent extraction0.0112 PercentStandard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier
IsopimpinellinBarkSolvent extraction0.0122 PercentStandard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier
Quinoline alkaloidsSeedSolvent extraction0.0012 PercentStandard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier
Quinoline alkaloidsBarkSolvent extraction≥ 0.0026 PercentStandard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier
Quinoline alkaloidsBarkSolvent extraction≤ 0.0052 PercentStandard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier
Quinoline alkaloidsBarkSolvent extraction≤ 0.0052 PercentStandard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier
Quinoline alkaloidsBarkSolvent extraction≥ 6e-04 PercentStandard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier
ScopoletinBarkSolvent extraction0.0015 PercentStandard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier
SynephrineSeedSolvent extractionIR and Raman SpectroscopyNo resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Froldi, Guglielmina., Bertin, Riccardo., Secchi, Enrico., Zagotto, Giuseppe., Martinez-Vazquez, Mariano., Garcia-Argaez, Aida. Vasorelaxation by extracts of Casimiroa spp. in rat resistance vessels and pharmacological study of cellular mechanisms . Journal of ethnopharmacology, 2011, vol. 134, no. 3, p. 637-643. DOI
  2. Nagai, Hiroyuki., Tanaka, Toshiyuki., Goto, Tsuyoshi., Kusudo, Tatsuya., Takahashi, Nobuyuki., Kawada, Teruo. Phenolic compounds from leaves of Casimiroa edulis showed adipogenesis activity . Bioscience biotechnology and biochemistry, 2014, vol. 78, no. 2, p. 296-300. DOI
  3. Bertin, R., Chen, Z., Martinez-Vazquez, M., Garcia-Argaez, A., Froldia, G. Vasodilation and radical-scavenging activity of imperatorin and selected coumarinic and flavonoid compounds from genus Casimiroa . Phytomedicine, 2014, vol. 21, no. 5, p. 586-594. DOI
  4. Awaad, Amani S., Maitland, Derek J., Moneir, Samar M. New alkaloids from Casimiroa edulis fruits and their pharmacological activity . Chemistry of natural compounds, 2007, vol. 43, no. 5, p. 576-580. DOI
  5. Awaad, Amani S., Al-Jaber, Nabilah A., Soliman, Gamal A., Al-Outhman, Mounerah R., Zain, Mohamed E., Moses, John E., El-Meligy, Reham M. New Biological Activities of Casimiroa edulis Leaf Extract and Isolated Compounds . Phytotherapy research, 2012, vol. 26, no. 3, p. 452-457. DOI
  6. Ito, A., Shamon, LA., Yu, BY., Mata-Greenwood, E., Lee, SK., van Breemen, RB., Mehta, RG., Farnsworth, NR., Fong, HHS., Pezzuto, JM., Kinghorn, AD. Antimutagenic constituents of Casimiroa edulis with potential cancer chemopreventive activity . Journal of agricultural and food chemistry, 1998, vol. 46, no. 9, p. 3509-3516. DOI
  7. Kincl, F.A., Romo, J., Rosenkranz, G., Sondhkimer, F. The constituents of casimiroa edulis llave et lex. Part I. The seed.*. Journal of the chemical society (resumed), 1956, p. 4150-4157.
  8. Iriarte, J., Kincl, F.A., Rosenkranz, G., Sondheimer, F. The constituents of casimiroa edulis llave et lex. Part II.* The bark. Journal of the chemical society (resumed), 1956, p. 4158-4160.
  9. Power, F.B., Callan, T. CCXXVI. - The constituents of the seeds of Casimiroa edulis. Journal of the chemical society, transactions, 1911, vol. 99, p. 1993-2010. DOI
  10. Magos, GA., Vidrio, H., Reynolds, WF., Enriquez, RG. Pharmacology of Casimiroa edulis IV. Hypotensive effects of compounds isolated from methanolic extracts in rats and guinea pigs . Journal of ethnopharmacology, 1999, vol. 64, no. 1, p. 35-44.
  11. Garcia-Argaez, Aida N., Gonzalez-Lugo, Nadia M., Marquez, Carmen., Martinez-Vazquez, Mariano. Coumarins present in species of the genus Casimiroa. Revista de la sociedad quimica de mexico, 2003, vol. 47, no. 2, p. 151-154.
  12. Awaad, A. S., Soliman, G. A. Essential oil, coumarins, and flavonoids of Casimiroa edulis leaves growing in Egypt and their biological activities. Egyptian journal of biomedical sciences, 2004, vol. 15, p. 42-58.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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