Cassia fistula

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 14 licensed products naming Cassia fistula as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

What the records describe

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Genotoxicity testing

Outcomes of genotoxicity assays as recorded in the source. A negative assay is a result under those test conditions, not a clearance.

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

1. Lee, CK., Lee, PH., Kuo, YH. The chemical constituents from the aril of Cassia fistula L.. Journal of the chinese chemical society, 2001, vol. 48, no. 6A, p. 1053-1058.
2. Khan, M., Shingare, M.S., Siddiqui, A.R., Angadi, S.S., Maske, P.V., Yahya, M., Siddiqui, M.A. TLC-colourimetric estimation of free and combined forms of chrysophanol, emodin and physcione in some Cassia species. Indian journal of pharmaceutical sciences, 2005, vol. 67, no. 6, p. 767-770.
3. Salem, AZM., Salem, MZM., El-Adawy, MM., Robinson, PH. Nutritive evaluations of some browse tree foliages during the dry season: Secondary compounds, feed intake and in vivo digestibility in sheep and goats. ANIMAL FEED SCIENCE AND TECHNOLOGY, 2006, vol. 127, no. 3-4, p. 251-267. DOI
4. Sakulpanich, A., Chewchinda, S., Sithisarn, P., Gritsanapan, W. Standardization and toxicity evaluation of Cassia fistula pod pulp extract for alternative source of herbal laxative drug. Pharmacognosy journal, 2012, vol. 4, no. 28, p. 6-12. DOI
5. Mukhopadhyay, MJ., Saha, A., Dutta, A., De, B., Mukherjee, A. Genotoxicity of sennosides on the bone marrow cells of mice. Food and chemical toxicology, 1998, vol. 36, no. 11, p. 937-940. DOI
6. Morinaga, Osamu., Uto, Takuhiro., Sakamoto, Seiichi., Tanaka, Hiroyuki., Shoyama, Yukihiro. Enzyme-linked immunosorbent assay for total sennosides using anti-sennoside A and anti-sennoside B monoclonal antibodies. Fitoterapia, 2009, vol. 80, no. 1, p. 28-31.
7. Pandey, Prabhash K., Singh, Dushyant., Singh, Ranjan., Sinha, Mrityunjay K., Singh, Sangram., Jamal, Farrukh. Cassia fistula seed's trypsin inhibitor(s) as antibiosis agent in Helicoverpa armigera pest management . Biocatalysis and agricultural biotechnology, 2016, vol. 6, p. 202-208. DOI
8. Bhakta, T., Deb, P.K., Bhaumik, K.N., Saha, J. Pharmacognostic investigation, acute toxicity studies and isolation of steroidal compound from the leaves of Cassia fistula Linn. International journal of pharmaceutical sciences review and research, 2014, vol. 25, no. 1, p. 210-214.
9. Li, L., Xu, W.-X., Liu, C.-B., Zhang, C.-M., Zhao, W., Shang, S.-Z., Deng, L., Guo, Y.-D. A new anthraquinones from Cassia fistula and its cytotoxicity. Asian journal of chemistry, 2015, vol. 27, no. 9, p. 3527-3528. DOI
10. Zhou, Min., Xing, Huan-Huan., Yang, Yan., Wang, Yue-De., Zhou, Kun., Dong, Wei., Li, Gan-Peng., Hu, Wei-Yao., Liu, Qiang., Li, Xue-Mei., . Three new anthraquinones from the twigs of Cassia fistula and their bioactivities. Journal of asian natural products research, 2017, p. Ahead of Print.
11. Veerachari, U., Bopaiah, A.K. Preliminary phyto-chemical evaluation of the leaf extract of five cassia species. Journal of chemical and pharmaceutical research, 2011, vol. 3, no. 5, p. 574-583.

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