Botanical species · safety record

Centaurea benedicta

The EFSA Compendium of Botanicals holds 13 constituent measurements and 4 adverse-effect records for Centaurea benedicta. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Centaurea benedicta (L.) L.

13Constituent measurements

4Safety records

4Cited sources

0Licensed products (Canada)

Also recorded as

Cnicus benedictus L.

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Absinthin	Aerial part of plants	—	—	—	Resolve DOI
Arctigenin	Fruit unspecified	Solvent extraction	0.051 Millimol/100 Gramm	GC-MS	Resolve DOI
Arctiin	Fruit unspecified	Solvent extraction	4.4 Millimol/100 Gramm	GC-MS	Resolve DOI
Cinnamaldehyde	Aerial part of plants	Essential oil	—	—	Resolve DOI
Cnicin	Aerial part of plants	—	≥ 0.2 Percent	—	Resolve DOI
Cnicin	Aerial part of plants	—	≤ 0.7 Percent	—	Resolve DOI
Fenchone	Aerial part of plants	Essential oil	—	—	Resolve DOI
Matairesinol	Fruit unspecified	Solvent extraction	1.33 Millimol/100 Gramm	GC-MS	Resolve DOI
Nortracheloside	Aerial part of plants	—	—	—	Resolve DOI
Polyacetylene derivatives	Unspecified	Solvent extraction	—	—	Resolve DOI
Salonitenolide	Unspecified	Solvent extraction	—	—	Resolve DOI
Trachelogenin	Aerial part of plants	—	—	—	Resolve DOI
Cnicin	Aerial part of plants	Solvent extraction	0.63 Percent	IR and Raman Spectroscopy	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Digestive	Stomach	Aerial part of plants	Solvent extraction	Human (as organism)	Case report	Resolve DOI
Hemopoietic	Cardiovascular / haematological	Aerial part of plants	—	Human (as organism)	Not reported	Resolve DOI
Digestive	Digestive: pancreas	Aerial part of plants	Solvent extraction	—	In vitro	No resolvable identifier
Digestive	Digestive: pancreas	Aerial part of plants	Solvent extraction	—	In vitro	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Solyomvary, Anna., Toth, Gergo., Kraszni, Marta., Noszal, Bela., Molnar-Perl, Ibolya., Boldizsar, Imre. Identification and quantification of lignans and sesquilignans in the fruits of Cnicus benedictus L.: Quantitative chromatographic and spectroscopic approaches. MICROCHEMICAL JOURNAL, 2014, vol. 114, p. 238-246. DOI
Ulbricht, Catherine., Basch, Ethan., Dacey, Cynthia., Dith, Sophanna., Hammerness, Paul., Hashmi, Sadaf., Seamon, Erica., Vora, Mamta., Weissner, Wendy. An Evidence-Based Systematic Review of Blessed Thistle (Cnicus benedictus) by the Natural Standard Research Collaboration. Journal of Dietary Supplements, 2008, vol. 5, no. 4, p. 422-437. DOI
Bloszyk, E., Geppert, B., Drozdz, Bohdan. Sesquiterpene lactones of the Compositae. Part XX. Quantitative determination of sesquiterpene lactones in plant material by infrared spectroscopy. Planta Medica, 1978, p. 79-86.
Slanc, Petra., Doljak, Bojan., Kreft, Samo., Lunder, Mojca., Janes, Damjan., Strukelj, Borut. Screening of selected food and medicinal plant extracts for pancreatic lipase inhibition. Phytotherapy Research, 2009, p. 874-877.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature