Botanical species · safety record

Chamaeleon gummifer

The EFSA Compendium of Botanicals holds 4 constituent measurements and 4 adverse-effect records for Chamaeleon gummifer. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Chamaeleon gummifer (L.) Cass.

4Constituent measurements

4Safety records

5Cited sources

0Licensed products (Canada)

Also recorded as

Carlina gummifera (L.) Less.
Atractylis gummifera Salzm. ex L.

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Atractyloside	Roots and other underground parts	Solvent extraction	3.9 Milligram/gram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Atractyloside	Roots and other underground parts	—	≥ 0.12 Percent	—	Resolve DOI
Atractyloside	Roots and other underground parts	—	≤ 1.57 Percent	—	Resolve DOI
Carboxyatractyloside	Roots and other underground parts	Solvent extraction	6.2 Milligram/gram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Hepatotoxicity	Neurologic	Roots and other underground parts	—	Human (as organism)	Case report	Resolve DOI
Hepatotoxicity	Digestive	Roots and other underground parts	Solvent extraction	Human (as organism)	Case report	Resolve DOI
Hepatotoxicity	Liver	Stem / stalk	—	Human (as organism)	Case report	No resolvable identifier
Hepatotoxicity	Stomach	Roots and other underground parts	—	Human (as organism)	Case report	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Stickel, Felix., Egerer, Gerlinde., Seitz, Helmut Karl. Hepatotoxicity of botanicals. Public health nutrition, 2000, vol. 3, no. 2, p. 113-124. DOI
Hamouda, C., Amamou, M., Thabet, H., Yacoub, M., Hedhili, A., Bescharnia, F., Ben Salah, N., Zhioua, M., Abdelmoumen, S., Ben Brahim, NE. Plant poisonings from herbal medication admitted to a Tunisian toxicologic intensive care unit, 1983-1998 . Veterinary and human toxicology, 2000, vol. 42, no. 3, p. 137-141.
Carlier, Jeremy., Romeuf, Ludovic., Guitton, Jerome., Priez-Barallon, Cedric., Bevalot, Fabien., Fanton, Laurent., Gaillard, Yvan. A Validated Method for Quantifying Atractyloside and Carboxyatractyloside in Blood by HPLC-HRMS/MS, a Non-Fatal Case of Intoxication with Atractylis gummifera L. . Journal of analytical toxicology, 2014, vol. 38, no. 9, p. 619-627. DOI
Daniele, C., Dahamna, S., Firuzi, O., Sekfali, N., Saso, L., Mazzanti, G. Atractylis gummifera L. poisoning: an ethnopharmacological review. Journal of ethnopharmacology, 2005, vol. 97, no. 2, p. 175-181. DOI
Abdualmjid, R.J., Sergi, C. Hepatotoxic botanicals - An evidence-based systematic review. Journal of pharmacy and pharmaceutical sciences, 2013, vol. 16, no. 3, p. 376-404.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature