Botanical species · safety record

Chiococca alba

The EFSA Compendium of Botanicals holds 5 constituent measurements and 8 adverse-effect records for Chiococca alba. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Chiococca alba (L.) Hitchc.

5Constituent measurements

8Safety records

5Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Chiococcasaponins	Roots and other underground parts	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Merilactone	Roots and other underground parts	Solvent extraction	—	—	Resolve DOI
Coumarins	Leaves	Solvent extraction	—	Chromatographic tests	No resolvable identifier
Matairesinol	Leaves	Solvent extraction	—	Chromatographic tests	No resolvable identifier
Quinoline alkaloids	—	—	—	Nuclear Magnetic Resonance (NMR)	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Hepatotoxicity	Liver	Roots and other underground parts	Solvent extraction	House mouse (as animal)	Acute toxicity	Resolve DOI
Hepatotoxicity	Liver	Roots and other underground parts	Solvent extraction	House mouse (as animal)	Acute toxicity	Resolve DOI
Irritation	Digestive	Roots and other underground parts	Solvent extraction	House mouse (as animal)	Acute toxicity	Resolve DOI
Irritation	Digestive	Roots and other underground parts	Solvent extraction	House mouse (as animal)	Acute toxicity	Resolve DOI
Nephrotoxicity	Urogenital: kidneys	Roots and other underground parts	Solvent extraction	House mouse (as animal)	Acute toxicity	Resolve DOI
Nephrotoxicity	Urogenital: kidneys	Roots and other underground parts	Solvent extraction	House mouse (as animal)	Acute toxicity	Resolve DOI
Neurotoxicity	Neurologic	Roots and other underground parts	Solvent extraction	House mouse (as animal)	Short-term toxicity	Resolve DOI
Neurotoxicity	Neurologic	Roots and other underground parts	Solvent extraction	House mouse (as animal)	Short-term toxicity	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Gazda, VE., Gomes-Carneiro, MR., Barbi, NS., Paumgartten, FJR. Toxicological evaluation of an ethanolic extract from Chiococca alba roots. JOURNAL OF ETHNOPHARMACOLOGY, 2006, vol. 105, no. 1-2, p. 187-195. DOI
Borges, Ricardo Moreira., Valenca, Samuel Santos., Lopes, Alan Aguiar., Barbi, Nancy dos Santos., Ribeiro da Silva, Antonio Jorge. Saponins from the roots of Chiococca alba and their in vitro anti-inflammatory activity. PHYTOCHEMISTRY LETTERS, 2013, vol. 6, no. 1, p. 96-100. DOI
ELHAFIZ, MAA., WENIGER, B., QUIRION, JC., ANTON, R. KETOALCOHOLS, LIGNANS AND COUMARINS FROM CHIOCOCCA-ALBA. PHYTOCHEMISTRY, 1991, vol. 30, no. 6, p. 2029-2031.
KITAHARA, Y., SHIMIZU, M., KUBO, A. SYNTHESIS OF NEW QUINOLINE ALKALOIDS OF CHIOCOCCA-ALBA. HETEROCYCLES, 1990, vol. 31, no. 11, p. 2085-2090.
Borges-Argaez, R., Medina-Baizabal, L., May-Pat, F., Waterman, PG., Pena-Rodriguez, LM. Merilactone, an unusual C-19 metabolite from the root extract of Chiococca alba. JOURNAL OF NATURAL PRODUCTS, 2001, vol. 64, no. 2, p. 228-231. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature