Botanical species · safety record
Chondrodendron platyphyllum
The EFSA Compendium of Botanicals holds 6 constituent measurements for Chondrodendron platyphyllum. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Chondrodendron platyphyllum (A.St.-Hil.) Miers
Regulatory presence
No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.
What the records describe
Constituents measured
- Bisbenzylisoquinoline alkaloids3
- 1-bebeerine1
- 12-o-methylcurine1
- Chondrocurine1
Plant parts
- Roots and other underground parts3
- Leaves2
- Unspecified1
Preparations
- Solvent extraction1
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| 12-o-methylcurine | Roots and other underground parts | — | — | — | Resolve DOI |
| Bisbenzylisoquinoline alkaloids | Roots and other underground parts | — | — | Unspecified | Resolve DOI |
| Bisbenzylisoquinoline alkaloids | Leaves | — | — | — | Resolve DOI |
| 1-bebeerine | Roots and other underground parts | — | — | — | No resolvable identifier |
| Bisbenzylisoquinoline alkaloids | Unspecified | Solvent extraction | — | — | No resolvable identifier |
| Chondrocurine | Leaves | — | — | Nuclear Magnetic Resonance (NMR) | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Souccar, C., Borras, M R., Corrado, A P., Lima-Landman, M T., Lapa, A J. Natural probes for cholinergic sites: L-bebeerine actions on the neuromuscular transmission, the nicotinic receptor/ionic channel complex, and contraction of skeletal muscles. . Acta physiologica, pharmacologica et therapeutica latinoamericana : organo de la asociacion latinoamericana de ciencias fisiologicas y [de] la asociacion latinoamericana de farmacologia, 1999, vol. 49, no. 4, p. 268-78.
- Bick, I. R. C., Baldas, J., Porter, Q. N., Vernengo, M. J. Structure and stereochemistry of the alkaloid chondrofoline. Journal of the chemical society [section] d: chemical communications, 1971, vol. (3), p. 132-3.
- Leite, Fagner Carvalho., Ribeiro-Filho, Jaime., Costa, Hermann Ferreira., Rodrigues Salgado, Paula Regina., Calheiros, Andrea Surrage., Carneiro, Alan Brito., de Almeida, Reinaldo Nobrega., Dias, Celidarque da Silva., Bozza, Patricia T., Piuvezam, Marcia Regina. Curine, an Alkaloid Isolated from Chondrodendron platyphyllum Inhibits Prostaglandin E-2 in Experimental Models of Inflammation and Pain . Planta medica, 2014, vol. 80, no. 13, p. 1072-1078. DOI
- Brazil, Oswaldo V., Seba, Roched A., Campos, Joao S. Curarizing properties of the alkali-insoluble methylated alkaloids of Chondrodendron platyphyllum (St. Hil.) Miers. Bol. inst. vital brazil, 1944, vol. No. 26, p. 8-22.
- King, H. Curare alkaloids. Part V. Alkaloids of some chondrodendron species and the origin of radix pareir� brav�. Journal of the chemical society (resumed), 1940, p. 737-746. DOI
- Guedes, DN., Barbosa, JM., Lemos, VS., Cortes, SF. Mechanism of the vasodilator effect of 12-O-methylcurine in rat aortic rings . Journal of pharmacy and pharmacology, 2002, vol. 54, no. 6, p. 853-858. DOI
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
Continue
Europe PMC
Every record indexed for this species, resolvable and re-runnable.
All speciesSubstance index
Search and browse every species this world holds under source and hash.
Before anything elseSafety Centre
Interactions, contraindications and the escalation boundary this world does not cross.
In its own termsTraditions
How the living traditions approach preparation, use and context.