Botanical species · safety record

Chondrodendron platyphyllum

The EFSA Compendium of Botanicals holds 6 constituent measurements for Chondrodendron platyphyllum. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Chondrodendron platyphyllum (A.St.-Hil.) Miers

6Constituent measurements
0Safety records
6Cited sources
0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

  • Bisbenzylisoquinoline alkaloids3
  • 1-bebeerine1
  • 12-o-methylcurine1
  • Chondrocurine1

Plant parts

  • Roots and other underground parts3
  • Leaves2
  • Unspecified1

Preparations

  • Solvent extraction1

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
12-o-methylcurineRoots and other underground partsResolve DOI
Bisbenzylisoquinoline alkaloidsRoots and other underground partsUnspecifiedResolve DOI
Bisbenzylisoquinoline alkaloidsLeavesResolve DOI
1-bebeerineRoots and other underground partsNo resolvable identifier
Bisbenzylisoquinoline alkaloidsUnspecifiedSolvent extractionNo resolvable identifier
ChondrocurineLeavesNuclear Magnetic Resonance (NMR)No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Souccar, C., Borras, M R., Corrado, A P., Lima-Landman, M T., Lapa, A J. Natural probes for cholinergic sites: L-bebeerine actions on the neuromuscular transmission, the nicotinic receptor/ionic channel complex, and contraction of skeletal muscles. . Acta physiologica, pharmacologica et therapeutica latinoamericana : organo de la asociacion latinoamericana de ciencias fisiologicas y [de] la asociacion latinoamericana de farmacologia, 1999, vol. 49, no. 4, p. 268-78.
  2. Bick, I. R. C., Baldas, J., Porter, Q. N., Vernengo, M. J. Structure and stereochemistry of the alkaloid chondrofoline. Journal of the chemical society [section] d: chemical communications, 1971, vol. (3), p. 132-3.
  3. Leite, Fagner Carvalho., Ribeiro-Filho, Jaime., Costa, Hermann Ferreira., Rodrigues Salgado, Paula Regina., Calheiros, Andrea Surrage., Carneiro, Alan Brito., de Almeida, Reinaldo Nobrega., Dias, Celidarque da Silva., Bozza, Patricia T., Piuvezam, Marcia Regina. Curine, an Alkaloid Isolated from Chondrodendron platyphyllum Inhibits Prostaglandin E-2 in Experimental Models of Inflammation and Pain . Planta medica, 2014, vol. 80, no. 13, p. 1072-1078. DOI
  4. Brazil, Oswaldo V., Seba, Roched A., Campos, Joao S. Curarizing properties of the alkali-insoluble methylated alkaloids of Chondrodendron platyphyllum (St. Hil.) Miers. Bol. inst. vital brazil, 1944, vol. No. 26, p. 8-22.
  5. King, H. Curare alkaloids. Part V. Alkaloids of some chondrodendron species and the origin of radix pareir� brav�. Journal of the chemical society (resumed), 1940, p. 737-746. DOI
  6. Guedes, DN., Barbosa, JM., Lemos, VS., Cortes, SF. Mechanism of the vasodilator effect of 12-O-methylcurine in rat aortic rings . Journal of pharmacy and pharmacology, 2002, vol. 54, no. 6, p. 853-858. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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