Botanical species · safety record

Cichorium intybus

The EFSA Compendium of Botanicals holds 3 constituent measurements and 2 adverse-effect records for Cichorium intybus. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Cichorium intybus L.

3Constituent measurements

2Safety records

4Cited sources

204Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 204 licensed products naming Cichorium intybus as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Dry
Fresh

Source material stated

Cichorium intybus - Root
Flower
Flowers
Inulin
Leaf
New material
Root
Root (standardized extract)

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Coumarins	Seed	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Harman	Unspecified	Solvent extraction	0.26 Microgram/gram	HPLC with standard detection methods	Resolve DOI
Norharmane	Unspecified	Solvent extraction	0.05 Microgram/gram	HPLC with standard detection methods	Resolve DOI

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Neurotoxicity	Neurologic: central nervous system	Aerial part of plants	Raw, no heat treatment	Human (as organism)	Case report	No resolvable identifier
Reproductive	Testes	Roots and other underground parts	Powder	House mouse (as animal)	Short-term toxicity	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Roy, Choudhury A., Bhatt, Venkatakrishna H. Spermatogenic impairment in mice treated with Cichorium-intybus aqueous root suspension . Indian journal of industrial medicine, 1996, vol. 42, no. 4, p. 217-218.
Ram�rez S�nchez, Manuel Segundo., Mujica, Yovanny Avelino., Pascuzzo, Lima Carmine., Ram�rez Fernandez, Manuel J. Probable intoxicaci�n por achicoria (cichorium intybus). Archivos venezolanos de puericultura y pediatr�a, 2007, vol. 70, no. 2, p. 69-72.
Atta-Ur-Rahman., Zareen, Seema., Choudhary, M. Iqbal., Akhtar, M. Nadeern., Khan, Shamsun Nahar. alpha-glucosidase inhibitory activity of triterpenoids from Cichorium [intybus]. Journal of natural products, 2008, vol. 71, no. 5, p. 910-913. DOI
Wojtowicz, E., Zawirska-Wojtasiak, R., Przygonski, K., Mildner-Szkudlarz, S. Bioactive beta-carbolines norharman and harman in traditional and novel raw materials for chicory coffee. Food chemistry, 2015, vol. 175, p. 280-283. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

Continue

Independent literature