Botanical species · safety record

Cinnamomum cassia

The EFSA Compendium of Botanicals holds 12 constituent measurements for Cinnamomum cassia. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Cinnamomum cassia (L.) J.Presl

12Constituent measurements

0Safety records

5Cited sources

135Licensed products (Canada)

Also recorded as

Cinnamomum aromaticum Nees

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 135 licensed products naming Cinnamomum cassia as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Source material stated

Bark
Bark extract
Branch (Fried)
Branch bark
Branch(es)
Cinnamomum aromaticum - Branch bark
Cinnamomum aromaticum - Stem bark
Cinnamomum cassia

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Benzaldehyde	Wood	Essential oil	2 Percent	GC-FID-MS	Resolve DOI
Benzoic acid	Wood	Solvent extraction	20 Milligram	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Cinnamaldehyde	Wood	Solvent extraction	11.2 Gram	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Cinnamaldehyde	Wood	Essential oil	81.6 Percent	GC-FID-MS	Resolve DOI
Cinnamaldehyde	Bark	Solvent extraction	5.8 Milligram/gram	GC-MS	Resolve DOI
Coumarin	Wood	Solvent extraction	874.6 Milligram	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
P-coumaric acid	Wood	Essential oil	2.3 Percent	GC-FID-MS	Resolve DOI
Syringaresinol	Wood	Solvent extraction	38.8 Milligram	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Cinnamaldehyde	Bark	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Coumarin	Bark	—	≤ 12230 Milligram/kilogram	Unspecified	No resolvable identifier
Coumarin	Bark	—	≥ 700 Milligram/kilogram	Unspecified	No resolvable identifier
Eugenol	Bark	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Abraham, Klaus., Woehrlin, Friederike., Lindtner, Oliver., Heinemeyer, Gerhard., Lampen, Alfonso. Toxicology and risk assessment of coumarin: Focus on human data. Molecular nutrition & food research, 2010, vol. 54, no. 2, p. 228-239.
Kim, Junheon., Jang, Miyeon., Shin, Eunsik., Kim, Jeongmin., Lee, Si Hyeock., Park, Chung Gyoo. Fumigant and contact toxicity of 22 wooden essential oils and their major components against Drosophila suzukii (Diptera: Drosophilidae) . Pesticide biochemistry and physiology, 2016, vol. 133, p. 35-43. DOI
Kim, Geum Jin., Lee, Jong Yeong., Choi, Hyun Gyu., Kim, So Young., Kim, Eonmi., Shim, Sang Hee., Nam, Joo-Won., Kim, Sang-Hyun., Choi, Hyukjae. Cinnamomulactone, a new butyrolactone from the twigs of Cinnamomum cassia and its inhibitory activity of matrix metalloproteinases . Archives of pharmacal research, 2017, vol. 40, no. 3, p. 304-310. DOI
Lee, HS., Kim, SY., Lee, CH., Ahn, YJ. Cytotoxic and mutagenic effects of Cinnamomum cassia bark-derived materials . Journal of microbiology and biotechnology, 2004, vol. 14, no. 6, p. 1176-1181.
Wondrak, Georg Thomas., Villeneuve, Nicole F., Lamore, Sarah D., Bause, Alexandra S., Jiang, Tao., Zhang, Donna D. The Cinnamon-Derived Dietary Factor Cinnamic Aldehyde Activates the Nrf2-Dependent Antioxidant Response in Human Epithelial Colon Cells . Molecules, 2010, vol. 15, no. 5, p. 3338-3355. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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