Botanical species · safety record

Citrus aurantiifolia

The EFSA Compendium of Botanicals holds 24 constituent measurements for Citrus aurantiifolia. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Citrus aurantiifolia (Christm.) Swingle

24Constituent measurements

0Safety records

8Cited sources

46Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 46 licensed products naming Citrus aurantiifolia as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Source material stated

Citrus aurantiifolia - Unripe fruit peel
Citrus aurantiifolia - fruit
Edible fruit part
Fruit
Fruit flesh
Fruit peel
New material
Peel

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
1,8-cineole	Leaves	Essential oil	5.3 Percent	GC-MS	Resolve DOI
Bergamottin	Fruit peel	Solvent extraction	29.7 Microgram/100 millilitre	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Bergapten	Fruit peel	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Camphor	Leaves	Essential oil	19.9 Percent	GC-MS	Resolve DOI
Coumarins	Fruit peel	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Coumarins	Unspecified	Essential oil	—	HPLC-DAD	Resolve DOI
Furanocoumarins	Fruit peel	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Furanocoumarins	Unspecified	Essential oil	—	HPLC-DAD	Resolve DOI
Isopimpinellin	Fruit peel	Solvent extraction	6862 Microgram/100 millilitre	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Isopimpinellin	Fruit peel	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Limettin	Fruit peel	Solvent extraction	52.6 Microgram/100 millilitre	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Limettin	Fruit peel	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Myrcene	Unspecified	Essential oil	≥ 1.2 Percent	GC-MS	Resolve DOI
Myrcene	Unspecified	Essential oil	≤ 1.3 Percent	GC-MS	Resolve DOI
Alkaloids	Roots and other underground parts	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Alkaloids	Fruit unspecified	—	—	Phytochemical screening	No resolvable identifier
Bergapten	Leaves	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Cardiac glycosides	Roots and other underground parts	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Fenchone	Fruit peel	Essential oil	15 Percent	Unspecified	No resolvable identifier
Imperatorin	Leaves	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Isobergapten	Leaves	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Isopimpinellin	Leaves	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Psoralen	Leaves	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Tannins	Fruit unspecified	—	—	Phytochemical screening	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Belewu, M.A., Olatunde, O.A., Giwa, T.A. Underutilized medicinal plants and spices: Chemical composition and phytochemical properties. Journal of Medicinal Plants Research, 2009, vol. 3, no. 12, p. 1099-1103.
Dugo, P., Mondello, L., Lamonica, G., Dugo, G. Characterization of cold-pressed Key and Persian lime oils by gas chromatography, gas chromatography mass spectroscopy, high-performance liquid chromatography, and physicochemical indices. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1997, vol. 45, no. 9, p. 3608-3616. DOI
Gorgus, E., Lohr, C., Raquet, N., Guth, S., Schrenk, D. Limettin and furocoumarins in beverages containing citrus juices or extracts. FOOD AND CHEMICAL TOXICOLOGY, 2010, vol. 48, no. 1, p. 93-98. DOI
Shalaby, N.M.M., Abd-Alla, H.I., Ahmed, H.H., Basoudan, N. Protective effect of Citrus sinensis and Citrus aurantifolia against osteoporosis and their phytochemical constituents. Journal of Medicinal Plants Research, 2011, vol. 5, no. 4, p. 579-588.
Nigg, H.N., Nordby, H.E., Beier, R.C., Dillman, A., Macias, C., Hansen, R.C. Phototoxic coumarins in limes. Food and Chemical Toxicology, 1993, vol. 31, no. 5, p. 331-335. DOI
Sandoval-Montemayor, Nallely E., Garcia, Abraham., Elizondo-Trevino, Elizabeth., Garza-Gonzalez, Elvira., Alvarez, Laura., del Rayo Camacho-Corona, Maria. Chemical Composition of Hexane Extract of Citrus aurantifolia and Anti-Mycobacterium tuberculosis Activity of Some of Its Constituents. MOLECULES, 2012, vol. 17, no. 9, p. 11173-11184. DOI
Ebana, R.U.B., Madunagu, B.E., Ekpe, E.D., Otung, I.N. Microbiological exploitation of cardiac glycosides and alkaloids from Garcinia kola, Borreria ocymoides, Kola nitida and Citrus aurantifolia. Journal of Applied Bacteriology, 1991, vol. 71, no. 5, p. 398-401.
Chaiyana, Wantida., Okonogi, Siriporn. Inhibition of cholinesterase by essential oil from food plant. PHYTOMEDICINE, 2012, vol. 19, no. 8-9, p. 836-839. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature