Botanical species · safety record

Citrus medica

The EFSA Compendium of Botanicals holds 5 constituent measurements and 2 adverse-effect records for Citrus medica. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Citrus medica L.

5Constituent measurements

2Safety records

3Cited sources

36Licensed products (Canada)

Also recorded as

Citrus limetta Risso

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 36 licensed products naming Citrus medica as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Source material stated

Citrus medica
Fruit
Fruit(s)
Ripe fruit(s)

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Myrcene	Fruit unspecified	Essential oil	2.1 Percent	GC-MS	Resolve DOI
Alkaloids	Seed	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Coumarins	Fruit unspecified	Essential oil	—	GC-MS	No resolvable identifier
Furanocoumarins	Fruit unspecified	Essential oil	—	GC-MS	No resolvable identifier
Myrcene	Fruit unspecified	Essential oil	—	GC-MS	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Reproductive	Urogenital	Seed	Solvent extraction	Rat (as animal)	Reproduction toxicity	No resolvable identifier
Reproductive	Urogenital	Seed	Solvent extraction	Rat (as animal)	Reproduction toxicity	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Di Giacomo, Angelo., Rispoli, Giuseppe. Sweet lemon Citrus limetta . I. Essential oil. Essenze, derivati agrumari, 1969, p. 115-123.
Menichini, Federica., Tundis, Rosa., Loizzo, Monica Rosa., Bonesi, Marco., Provenzano, Eugenio., de Cindio, Bruno., Menichini, Francesco. In vitro photo-induced cytotoxic activity of Citrus bergamia and C. medica L. cv. Diamante peel essential oils and identified active coumarins . Pharmaceutical biology, 2010, vol. 48, no. 9, p. 1059-1065. DOI
Sharangouda., Patil, Saraswati B. Antifertility principles from Citrus medica seeds: anti-implantation, abortifacient and phytochemical studies. Asian journal of experimental sciences, 2010, p. 155-161.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature