Botanical species · safety record

Citrus reticulata

The EFSA Compendium of Botanicals holds 16 constituent measurements for Citrus reticulata. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Citrus reticulata Blanco

16Constituent measurements

0Safety records

8Cited sources

1,575Licensed products (Canada)

Also recorded as

Citrus deliciosa Ten.

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 1,575 licensed products naming Citrus reticulata as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Dry
Extract Type TBA
Fresh
decoction
fluid
solid

Source material stated

Citrus Reticulata - Pericarp
Citrus reticulata
Citrus reticulata - Fruit
Citrus reticulata - Fruit peel
Citrus reticulata, pericarp of the ripe fruit
Dried peel
Dried pericarp
Dried pericarp of the ripe fruit

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Furanocoumarins	Fruit peel	Solvent extraction	≤ 52 Microgram/gram	HPLC-DAD	Resolve DOI
Furanocoumarins	Fruit peel	Solvent extraction	≥ 48 Microgram/gram	HPLC-DAD	Resolve DOI
Limonin	Seed	Solvent extraction	0.523 Milligram/gram	Capillary (Zone) Electrophoresis (CE or CZE)	Resolve DOI
Limonoids	Seed	Solvent extraction	—	Gelpermeation, High Performance Thin Layer Chromatography (HPTLC)	Resolve DOI
Melatonin	Fruit unspecified	Solvent extraction	150 Picogram/gram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Nomilin	Seed	Solvent extraction	0.45 Milligram/gram	Capillary (Zone) Electrophoresis (CE or CZE)	Resolve DOI
Coumarins	Fruit unspecified	—	—	Unspecified	No resolvable identifier
Lariciresinol	Fruit unspecified	Solvent extraction	57 Microgram/100 gram	LC-MS	No resolvable identifier
Lignans	Fruit unspecified	Solvent extraction	3 Microgram/100 gram	LC-MS	No resolvable identifier
Lignans, total	Fruit unspecified	Solvent extraction	81 Microgram/100 gram	LC-MS	No resolvable identifier
Limonoids	Seed	—	—	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Matairesinol	Fruit unspecified	Solvent extraction	1 Microgram/100 gram	LC-MS	No resolvable identifier
Myrcene	Fruit peel	Essential oil	27.52 Percent	GC-MS	No resolvable identifier
Pinoresinol	Fruit unspecified	Solvent extraction	21 Microgram/100 gram	LC-MS	No resolvable identifier
Synephrine	Fruit peel	Solvent extraction	≥ 2.2 Milligram/gram	HPLC-UV	No resolvable identifier
Synephrine	Fruit peel	Solvent extraction	≤ 8.97 Milligram/gram	HPLC-UV	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Jayaprakasha, GK., Singh, RP., Pereira, J., Sakariah, KK. Limonoids from Citrus reticulata and their moult inhibiting activity in mosquito Culex quinquefasciatus larvae. Phytochemistry, 1997, vol. 44, no. 5, p. 843-846. DOI
Milder, Ivon E. J., Arts, Ilja C. W., van de Putte, Betty., Venema, Dini P., Hollman, Peter C. H. Lignan contents of Dutch plant foods: A database including lariciresinol, pinoresinol, secoisolariciresinol and matairesinol. British journal of nutrition, 2005, vol. 93, no. 3, p. 393-402.
Ramirez-Pelayo, Cesar., Martinez-Quinones, Janio., Gil, Jesus., Durango, Diego. Coumarins from the peel of citrus grown in Colombia: composition, elicitation and antifungal activity. Heliyon, 2019, vol. 5, no. 6. DOI
Johns, Nutjaree Pratheepawanit., Johns, Jeffrey., Porasuphatana, Supatra., Plaimee, Preeyaporn., Sae-Teaw, Manit. Dietary Intake of Melatonin from Tropical Fruit Altered Urinary Excretion of 6-Sulfatoxymelatonin in Healthy Volunteers . Journal of agricultural and food chemistry, 2013, vol. 61, no. 4, p. 913-919. DOI
Wishart, DS., Jewison, T., Guo, AC., Wilson, M., Knox, C., Liu, Y., Djoumbou, Y., Mandal, R., Aziat, F., Dong, E., Bouatra, S., Sinelnikov, I., Arndt, D., Xia, J., Liu, P., Yallou, F., Bjorndahl, T., Perez-Pineiro, R., Eisner, R., Allen, F., Neveu, V., Greiner, R., Scalbert, A. (E)-Suberenol (HMDB30690).. Human metabolome database, 2012, vol. 3.0.
Moodley, VE., Mulholland, DA., Raynor, MW. Micellar electrokinetic capillary chromatography of limonoid glucosides from citrus seeds . Journal of chromatography a, 1995, vol. 718, no. 1, p. 187-193. DOI
Bui, Kim Anh., Duong, Anh Tuan. Isolation and structure elucidation of limonin and obacunone from seeds of Citrus nobilis in Vietnam. Tap chi hoa hoc, 2000, p. 25-30.
Inafuku-Teramoto, Sayuri., Suwa, Ryuichi., Fukuzawa, Yasunori., Kawamitsu, Yoshinobu. Polymethoxyflavones, Synephrine and Volatile Constitution of Peels of Citrus Fruit Grown in Okinawa. JOURNAL OF THE JAPANESE SOCIETY FOR HORTICULTURAL SCIENCE, 2011, vol. 80, no. 2, p. 214-224.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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