Botanical species · safety record

Cnidium monnieri

The EFSA Compendium of Botanicals holds 14 constituent measurements for Cnidium monnieri. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Cnidium monnieri (L.) Cusson

14Constituent measurements

0Safety records

4Cited sources

112Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 112 licensed products naming Cnidium monnieri as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Dry
Fresh

Source material stated

Cnidium monnieri - Fruit
Fruit
Fruit extract
Herb top
Ripe fruit(s)
Seed (powder)
Seed extract
Seed pod

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Bergapten	Seed	Solvent extraction	—	Chromatographic tests	Resolve DOI
Bergapten	Fruit peel	Solvent extraction	≤ 3.41 Milligram/gram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Columbianetin acetate	Fruit peel	Solvent extraction	≤ 7.86 Milligram/gram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Coumarins	Fruit unspecified	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Imperatorin	Seed	Solvent extraction	—	Chromatographic tests	Resolve DOI
Imperatorin	Fruit peel	Solvent extraction	≤ 7.25 Milligram/gram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Isopimpinellin	Seed	Solvent extraction	—	Chromatographic tests	Resolve DOI
Methoxsalen	Seed	Solvent extraction	—	Chromatographic tests	Resolve DOI
Oroselone	Fruit peel	Solvent extraction	≤ 8.26 Milligram/gram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Osthol	Seed	Solvent extraction	—	Chromatographic tests	Resolve DOI
Osthol	Fruit peel	Solvent extraction	≤ 16.41 Milligram/gram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Xanthotoxol	Fruit unspecified	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Dihydrocarvone	Unspecified	Essential oil	—	GC-MS	No resolvable identifier
Myrcene	Unspecified	Essential oil	—	GC-MS	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Liu, RM., Feng, L., Sun, AL., Kong, LY. Preparative isolation and purification of coumarins from Cnidium monnieri (L.) Cusson by high-speed counter-current chromatography. JOURNAL OF CHROMATOGRAPHY A, 2004, vol. 1055, no. 1-2, p. 71-76. DOI
Meng, Zhengmu., Jin, Changgen., Zhao, Shouxun., Ji, Jiang. GC-MS analysis of essential oil from Cnidium monnieri. Nanjing yaoxueyuan xuebao, 1986, p. 167-174.
Chen, Danxia., Wang, Jiajing., Jiang, Yunyun., Zhou, Tingting., Fan, Guorong., Wu, Yutian. Separation and determination of coumarins in Fructus cnidii extracts by pressurized capillary electrochromatography using a packed column with a monolithic outlet frit . Journal of pharmaceutical and biomedical analysis, 2009, vol. 50, no. 5, p. 695-702. DOI
Shin, Eunjin., Lee, Chul., Sung, Sang Hyun., Kim, Young Choong., Hwang, Bang Yeon., Lee, Mi Kyeong. Antifibrotic activity of coumarins from Cnidium monnieri fruits in HSC-T6 hepatic stellate cells. JOURNAL OF NATURAL MEDICINES, 2011, vol. 65, no. 2, p. 370-374. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature