Botanical species · safety record

Cnidoscolus aconitifolius

The EFSA Compendium of Botanicals holds 10 constituent measurements and 4 adverse-effect records for Cnidoscolus aconitifolius. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Cnidoscolus aconitifolius (Mill.) I.M.Johnst.

10Constituent measurements

4Safety records

7Cited sources

0Licensed products (Canada)

Also recorded as

Cnidoscolus chayamensa
Jatropha aconitifolia

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Oxalates	Leaves	—	0.85 Gram/kilogram	Unspecified	Resolve DOI
Alkaloids	Leaves	Solvent extraction	13.83 Milligram/kilogram	Phytochemical screening	No resolvable identifier
Alkaloids	Leaves	Solvent extraction	2.75 Percent	Phytochemical screening	No resolvable identifier
Alkaloids	Unspecified	Solvent extraction	0.69 Milligram/gram	Colorimetry, Spectroscopy (Spectrometry) and Photometry	No resolvable identifier
Anthraquinones	Leaves	Solvent extraction	0.072 Percent	Phytochemical screening	No resolvable identifier
Cyanogenic glycosides	Unspecified	Solvent extraction	5.02 Milligram/gram	Colorimetry, Spectroscopy (Spectrometry) and Photometry	No resolvable identifier
Hydrocyanic acid	Aerial part of plants	Solvent extraction	≥ 2.73 Milligram/100 gram	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Hydrocyanic acid	Aerial part of plants	Solvent extraction	≤ 4.25 Milligram/100 gram	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Saponins	Unspecified	Solvent extraction	4.45 Milligram/gram	Traditional analytical techniques (wet chemical tests)	No resolvable identifier
Saponins	Leaves	Solvent extraction	2.6 Percent	Phytochemical screening	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Reproductive	Testes	Leaves	Solvent extraction	Rat (as animal)	Reproduction toxicity	No resolvable identifier
Reproductive	Urogenital	Leaves	Solvent extraction	Rat (as animal)	Reproduction toxicity	No resolvable identifier
Reproductive	Urogenital	Leaves	Solvent extraction	Rat (as animal)	Reproduction toxicity	No resolvable identifier
Not stated	Cardiovascular / haematological	Leaves	Solvent extraction	Rat (as animal)	Short-term toxicity	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Jaramillo Jaramillo, Carmita., Jaramillo Espinoza, Anyi., D'Armas, Haydelba., Troccoli, Luis., Rojas de Astudillo, Luisa. Concentrations of alkaloids, cyanogenic glycosides, polyphenols and saponins in selected medicinal plants from Ecuador and their relationship with acute toxicity against Artemia salina . Revista de biologia tropical, 2016, vol. 64, no. 3, p. 1171-1184.
Oduse, Kayode A., Idowu, Micheal A., Adegbite, Adefolawe A. Chemical and phytochemical profile of some uncommon green leafy vegetables consumed in South West, Nigeria. Iosr journal of environmental science, toxicology and food technology, 2012, vol. 1, no. 3), 22-2, p. 5 pp.
Yakubu, M.T., Akanji, M.A., Oladiji, A.T., Olatinwo, A.O., Adesokan, A.A., Yakubu, M.O., Owoyele, B.V., Sunmonu, T.O., Ajao, M.S. Effect of Cnidoscolous aconitifolius (Miller) I.M. Johnston leaf extract on reproductive hormones of female rats. Iranian journal of reproductive medicine, 2008, vol. 6, no. 3, p. 149-155.
Adedapo, Adeolu Alex., Abatan, Matthew Oluwole., Olorunsogo, Olufunso Olabode. Effects of some plants of the spurge family on haematological and biochemical parameters in rats . Veterinarski arhiv, 2007, vol. 77, no. 1, p. 29-38.
Christopher Lucky, S., Edward, U.-N.O. Histological effects of aqueous leaf extract of Chaya(Cnidoscolus aconitifolius) on the testes and epididymis of adult wistar rats. Journal of medicine and biomedical research, 2014, vol. 13, no. 1, p. 120-128.
Donkoh, A., Atuahene, CC., Poku-Prempeh, YB., Twum, IG. The nutritive value of chaya leaf meal (Cnidoscolus aconitifolius (Mill.) Johnston): studies with broiler chickens . Animal feed science and technology, 1999, vol. 77, no. 1-2, p. 163-172. DOI
Gonz�lez-Laredo, R.F., Flores De La Hoya, M.E., Quintero-Ramos, M.J., Karchesy, J.J. Flavonoid and cyanogenic contents of chaya (Spinach Tree). Plant foods for human nutrition, 2003, vol. 58, no. 3, p. 1-8.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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