Botanical species · safety record

Coffea arabica

The EFSA Compendium of Botanicals holds 28 constituent measurements and 2 adverse-effect records for Coffea arabica. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Coffea arabica L.

28Constituent measurements

2Safety records

5Cited sources

406Licensed products (Canada)

Also recorded as

Coffea vulgaris Moench

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 406 licensed products naming Coffea arabica as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Dry
Extract Type TBA
Fresh
solid

Source material stated

Bean
Bean (standardized extract)
Coffea arabica - Fruit
Coffea arabica seed
Coffea canephora - Seed
Fruit
Fruit (standardized extract)
Fruit extract

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Biochanin-a	Seed	Solvent extraction	≥ 4.7 Microgram/kilogram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Biochanin-a	Seed	Solvent extraction	≤ 42.1 Microgram/kilogram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Caffeine	Seed	Solvent extraction	≥ 1.8 Millimole	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Caffeine	Unspecified	Solvent extraction	4.9 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Caffeine	Fruit unspecified	Solvent extraction	≤ 25.1 Millimole	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Caffeine	Seed	Solvent extraction	≤ 34.4 Millimole	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Caffeine	Leaves	—	—	Phytochemical screening	Resolve DOI
Caffeine	Fruit unspecified	Solvent extraction	≥ 0.45 Millimole	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Daidzein	Seed	Solvent extraction	≥ 3.4 Microgram/kilogram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Daidzein	Seed	Solvent extraction	≤ 25.3 Microgram/kilogram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Daidzin	Seed	Solvent extraction	≥ 12.6 Microgram/kilogram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Daidzin	Seed	Solvent extraction	≤ 95.2 Microgram/kilogram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Formononetin	Seed	Solvent extraction	≥ 4.3 Microgram/kilogram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Formononetin	Seed	Solvent extraction	≤ 46.7 Microgram/kilogram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Genistein	Seed	Solvent extraction	≥ 21.8 Microgram/kilogram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Genistein	Seed	Solvent extraction	≤ 40.7 Microgram/kilogram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Lariciresinol	Seed	Solvent extraction	≤ 2417.7 Microgram/kilogram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Lariciresinol	Seed	Solvent extraction	≥ 113.9 Microgram/kilogram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Secoisolarisiresinol	Seed	Solvent extraction	≤ 3694.3 Microgram/kilogram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Secoisolarisiresinol	Seed	Solvent extraction	≥ 172.6 Microgram/kilogram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Theobromine	Leaves	—	—	Phytochemical screening	Resolve DOI
Theophylline	Leaves	—	—	Phytochemical screening	Resolve DOI
Trigonelline	Fruit unspecified	Solvent extraction	≤ 32.6 Millimole	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Trigonelline	Fruit unspecified	Solvent extraction	≥ 0.22 Millimole	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Trigonelline	Seed	Solvent extraction	≥ 2.2 Millimole	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Trigonelline	Seed	Solvent extraction	≤ 49.7 Millimole	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Trigonelline	Unspecified	Solvent extraction	4.3 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Trigonelline	Leaves	—	—	Phytochemical screening	Resolve DOI

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Pulmonary and cardiac	Heart	Husk	—	Horse (as animal)	Short-term toxicity	Resolve DOI
Pulmonary and cardiac	Heart	Husk	—	Horse (as animal)	Short-term toxicity	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Angeloni, Simone., Navarini, Luciano., Khamitova, Gulzhan., Maggi, Filippo., Sagratini, Gianni., Vittori, Sauro., Caprioli, Giovanni. A new analytical method for the simultaneous quantification of isoflavones and lignans in 25 green coffee samples by HPLC-MS/MS. Food chemistry, 2020, vol. 325. DOI
Koshiro, Yukiko., Zheng, Xin-Qiang., Wang, Ming-Li., Nagai, Chifumi., Ashihara, Hiroshi. Changes in content and biosynthetic activity of caffeine and trigonelline during growth and ripening of Coffea arabica and Coffea canephora fruits . Plant science, 2006, vol. 171, no. 2, p. 242-250. DOI
Delfiol, Diego Jose Z., Oliveira-Filho, Jose P., Casalecchi, Fernanda L., Kievitsbosch, Thatiane., Hussni, Carlos A., Riet-Correa, Franklin., Araujo-, Joao P., Jr., Borges, Alexandre S. Equine poisoning by coffee husk (Coffea arabica L.). Bmc veterinary research, 2012, vol. 8. DOI
Hong, Bin Na., Yi, Tae Hoo., Kim, Sun Yeou., Kang, Tong Ho. High-Dosage Pyridoxine-Induced Auditory Neuropathy and Protection with Coffee in Mice. Biological & pharmaceutical bulletin, 2009, vol. 32, no. 4, p. 597-603. DOI
Chen, Xiumin. A review on coffee leaves: Phytochemicals, bioactivities and applications. Critical reviews in food science and nutrition, 2019, vol. 59, no. 6, p. 1008-1025. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature