Botanical species · safety record

Colchicum luteum

The EFSA Compendium of Botanicals holds 17 constituent measurements and 2 adverse-effect records for Colchicum luteum. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Colchicum luteum Baker

17Constituent measurements

2Safety records

7Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Alkaloids	Aerial part of plants	—	—	Unspecified	Resolve DOI
Alkaloids	Roots and other underground parts used as staple food	—	—	Unspecified	Resolve DOI
Alkaloids	Seed	—	—	Unspecified	Resolve DOI
Alkaloids	Unspecified	—	—	Unspecified	Resolve DOI
Alkaloids	Roots and other underground parts used as staple food	—	0.25 Percent	Unspecified	Resolve DOI
Alkaloids	Seed	—	0.4 Percent	Unspecified	Resolve DOI
Isoquinoline alkaloids	Aerial part of plants	—	—	Chromatographic tests	Resolve DOI
Isoquinoline alkaloids	Roots and other underground parts used as staple food	—	—	Chromatographic tests	Resolve DOI
Isoquinoline alkaloids	Seed	—	—	Chromatographic tests	Resolve DOI
Isoquinoline alkaloids	Seed	Solvent extraction	—	Chromatographic tests	Resolve DOI
Isoquinoline alkaloids	Unspecified	—	—	Chromatographic tests	Resolve DOI
Isoquinoline alkaloids	Aerial part of plants	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Isoquinoline alkaloids	Unspecified	—	—	Unspecified	Resolve DOI
Isoquinoline alkaloids	Unspecified	—	—	Unspecified	Resolve DOI
Alkaloids	Aerial part of plants	Solvent extraction	—	—	No resolvable identifier
Colchicin	Seed	Solvent extraction	≥ 0.26 Gram/100 gram	—	No resolvable identifier
Colchicin	Seed	Solvent extraction	≤ 0.27 Gram/100 gram	—	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Digestive	Digestive	Bulb / clove	—	Human (as organism)	Acute toxicity	Resolve DOI
Digestive	Digestive	Unspecified	Solvent extraction	—	In vitro	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Ahmad, Bashir., Khan, Haroon., Bashir, Shumaila., Nisar, M., Hassan, M. Inhibition activities of colchicum luteum baker on lipoxygenase and other enzymes . Journal of enzyme inhibition and medicinal chemistry, 2006, vol. 21, no. 4, p. 449-452. DOI
Sapra, Sameer., Bhalla, Yashika., Nandani., Sharma, Sahil., Singh, Gagandip., Nepali, Kunal., Budhiraja, Abhishek., Dhar, Kanaya L. Colchicine and its various physicochemical and biological aspects. Medicinal chemistry research, 2013, vol. 22, no. 2, p. 531-547. DOI
Sadykov, A. S., Yusupov, M. K., Chommadov, B. Composition of alkaloids in Colchicum luteum at different growth stages. Rastitel'nye resursy, 1969, vol. 5, no. 3, p. 441-4.
Wahid, M. A., Samiullah. Standardization of active principles of indigenous pharmacopoeial drugs found in West Pakistan. Pakistan journal of scientific and industrial research, 1960, vol. 3, p. 228-30.
Chommadov, B., Yusupov, M.K. Alkaloids of Colchicum luteum. Chemistry of natural compounds, 1985, vol. 21, no. 6, p. 770-773. DOI
Mukhamed'yarova, N.L., Yusupov, M.K., Aslanov, Kh.A., Sadykov, A.S. Structure and absolute configuration of collutine. Chemistry of natural compounds, 1976, vol. 11, no. 6, p. 781-783. DOI
Kametani, T., Koizumi, M. Phenethylisoquinoline Alkaloids. Alkaloids: chemistry and pharmacology, 1990, vol. 36, no. C, p. 171-223. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature