Botanical species · safety record
Comarum palustre
The EFSA Compendium of Botanicals holds 11 constituent measurements and 1 adverse-effect record for Comarum palustre. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Comarum palustre L.
Regulatory presence
No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.
What the records describe
Constituents measured
- Epigallocatechin gallate4
- Agrimoniin3
- Gallic acid1
- Gallotannins1
- Pedunculagin1
- Proanthocyanidins (condensed tannins)1
Plant parts
- Aerial part of plants5
- Flower2
- Leaves2
- Roots and other underground parts1
- Stem1
- Unspecified1
- stalk1
Preparations
- Solvent extraction12
Effect types
- Digestive1
Target tissues
- Digestive: pancreas1
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Agrimoniin | Leaves | Solvent extraction | 121.57 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Agrimoniin | Flower | Solvent extraction | 151.54 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Agrimoniin | Aerial part of plants | Solvent extraction | — | HPLC-UV | Resolve DOI |
| Epigallocatechin gallate | Flower | Solvent extraction | 0.53 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Epigallocatechin gallate | Leaves | Solvent extraction | 7.42 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Epigallocatechin gallate | Roots and other underground parts | Solvent extraction | 3.61 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Epigallocatechin gallate | Stem / stalk | Solvent extraction | 8.16 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Gallic acid | Aerial part of plants | Solvent extraction | — | HPLC-UV | Resolve DOI |
| Pedunculagin | Aerial part of plants | Solvent extraction | — | HPLC-UV | Resolve DOI |
| Proanthocyanidins (condensed tannins) | Aerial part of plants | Solvent extraction | — | HPLC-UV | Resolve DOI |
| Gallotannins | Unspecified | Solvent extraction | — | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
Recorded adverse effects
Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.
| Effect | Target tissue | Plant part | Preparation | Test organism | Test type | Source |
|---|---|---|---|---|---|---|
| Digestive | Digestive: pancreas | Aerial part of plants | Solvent extraction | — | In vitro | Resolve DOI |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Kashchenko, Nina I., Chirikova, Nadezhda K., Olennikov, Daniil N. Agrimoniin, an Active Ellagitannin from Comarum palustre Herb with Anti-alpha-Glucosidase and Antidiabetic Potential in Streptozotocin-Induced Diabetic Rats . Molecules, 2017, vol. 22, no. 1. DOI
- Olennikov, D. N. Ellagitannins and Other Phenolic Compounds from Comarum palustre. Chemistry of natural compounds, 2016, vol. 52, no. 4, p. 721-723. DOI
- Naumchik, G. N., Rozentsveig, P. E. Tannins in Comarum palustre. Trudy leningradskogo khimiko-farmatsevticheskogo instituta, 1964, vol. No. 17, p. 202-13.
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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