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Botanical species · safety record

Convolvulus arvensis

The EFSA Compendium of Botanicals holds 13 constituent measurements and 3 adverse-effect records for Convolvulus arvensis. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Convolvulus arvensis L.

13Constituent measurements
3Safety records
7Cited sources
5Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 5 licensed products naming Convolvulus arvensis as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Source material stated

  • New material
  • Plante entière
  • Whole plant (extract)

What the records describe

Constituents measured

  • Coumarins3
  • Alkaloids2
  • Anthraquinones1
  • Calcium oxalate1
  • Lectins1
  • P-coumaric acid1
  • Pyrrolizidine alkaloids1
  • Saponins1
  • Tannins1
  • Tropane alkaloids1

Plant parts

  • Live plants7
  • Aerial part of plants5
  • Roots and other underground parts2
  • Stem1
  • Unspecified1
  • stalk1

Preparations

  • Solvent extraction8
  • Fresh3
  • Drying (dehydration)1

Effect types

  • Digestive1
  • Hepatotoxicity1
  • Neurotoxicity1

Target tissues

  • Liver1
  • Neurologic1
  • Stomach1

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
Calcium oxalateStem / stalkDrying (dehydration)—Microscopic detectionResolve DOI
LectinsUnspecifiedSolvent extraction—Electrophoretical testsResolve DOI
Pyrrolizidine alkaloidsAerial part of plantsSolvent extraction—GC-MSResolve DOI
Tropane alkaloidsAerial part of plantsSolvent extraction—GC-MS/MSResolve DOI
AlkaloidsAerial part of plantsSolvent extraction—Phytochemical screeningNo resolvable identifier
AlkaloidsRoots and other underground parts——Gelpermeation, High Performance Thin Layer Chromatography (HPTLC)No resolvable identifier
AnthraquinonesLive plantsSolvent extraction—Phytochemical screeningNo resolvable identifier
CoumarinsAerial part of plants——Gelpermeation, High Performance Thin Layer Chromatography (HPTLC)No resolvable identifier
CoumarinsLive plants——Gelpermeation, High Performance Thin Layer Chromatography (HPTLC)No resolvable identifier
CoumarinsLive plantsSolvent extraction—Chromatographic testsNo resolvable identifier
P-coumaric acidRoots and other underground parts——Gelpermeation, High Performance Thin Layer Chromatography (HPTLC)No resolvable identifier
SaponinsAerial part of plantsSolvent extraction—Phytochemical screeningNo resolvable identifier
TanninsLive plantsSolvent extraction—Phytochemical screeningNo resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

EffectTarget tissuePlant partPreparationTest organismTest typeSource
DigestiveStomachLive plantsFreshHouse mouse (as animal)Short-term toxicityResolve DOI
HepatotoxicityLiverLive plantsFreshHouse mouse (as animal)Short-term toxicityResolve DOI
NeurotoxicityNeurologicLive plantsFreshHouse mouse (as animal)Short-term toxicityResolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Said, A.M., Numan, I.T., Hamad, M.N. Study of the cytotoxic and genotoxic effects for fractioniated extracts of Convolulus arvensis on bone marrow in mice. International Journal of Pharmacy and Pharmaceutical Sciences, 2013, vol. 5, no. SUPPL. 2, p. 303-305.
  2. TODD, FG., STERMITZ, FR., SCHULTHEIS, P., KNIGHT, AP., TRAUBDARGATZ, J. TROPANE ALKALOIDS AND TOXICITY OF CONVOLVULUS-ARVENSIS. PHYTOCHEMISTRY, 1995, vol. 39, no. 2, p. 301-303. DOI
  3. Saleem, Mohammad., Naseer, Faiza., Ahmad, Sohail., Baig, Kashif., Irshad, Iram. In vivo cytotoxic effects of methanol extract of Convolvulus arvensis on 7-12-dimethyl benz(a)antheracene (DMBA) induced skin carcinogenesis. African Journal of Pharmacy and Pharmacology, 2015, p. 397-404.
  4. Manbir, K., Kalia, A.N. Convolvulus arvensis - a useful weed. International journal of pharmacy and pharmaceutical sciences, 2012, vol. 4, no. 1, p. 38-40.
  5. Dubois, B., Peumans, WJ., Van Damme, EJM., Van Damme, J., Opdenakker, G. Regulation of gelatinase B (MMP-9) in leukocytes by plant lectins. Febs letters, 1998, vol. 427, no. 2, p. 275-278. DOI
  6. Khalil, A. M., El-Tawil, B. A. H., Ashy, M. A., Elbeih, F. K. A. Constituents of local plants. Part 8: Distribution of some coumarins in plants of different plant families grown in Saudi Arabia. Pharmazie, 1981, p. 569-571.
  7. DOAIGEY, AR. OCCURRENCE, TYPE, AND LOCATION OF CALCIUM-OXALATE CRYSTALS IN LEAVES AND STEMS OF 16 SPECIES OF POISONOUS PLANTS. AMERICAN JOURNAL OF BOTANY, 1991, vol. 78, no. 12, p. 1608-1616. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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