Coptis chinensis

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 656 licensed products naming Coptis chinensis as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

What the records describe

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Genotoxicity testing

Outcomes of genotoxicity assays as recorded in the source. A negative assay is a result under those test conditions, not a clearance.

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

1. Ma, Bingxin., Tong, Jing., Zhou, Gao., Mo, Qigui., He, Jingsheng., Wang, Youwei. Coptis chinensis inflorescence ameliorates hyperglycaemia in 3T3-L1 preadipocyte and streptozotocin-induced diabetic mice . Journal of functional foods, 2016, vol. 21, p. 455-462. DOI
2. Lee, Yong-Hoon., Kim, Duyeol., Lee, Mi Ju., Kim, Myoung Jun., Jang, Ho-Song., Park, Sun Hee., Lee, Jung-Min., Lee, Hye-Yeong., Han, Beom Seok., Son, Woo-Chan., Seok, Ji Hyeon., Lee, Jong Kwon., Jeong, Jayoung., Kang, Jin Seok., Kang, Jong-Koo. Subchronic toxicity study of Coptidis Rhizoma in rats. Journal of ethnopharmacology, 2014, vol. 152, no. 3, p. 457-463. DOI
3. Yi, Jun., Ye, Xiaoli., Wang, Dezhen., He, Kai., Yang, Yong., Liu, Xujing., Li, Xuegang. Safety evaluation of main alkaloids from Rhizoma Coptidis. Journal of ethnopharmacology, 2013, vol. 145, no. 1, p. 303-310. DOI
4. Huang, Ping., Qian, Xiaocui., Li, Junsong., Cui, Xiaobing., Chen, Lihua., Cai, Baochang., Tan, Shanzhong. Simultaneous Determination of 11 Alkaloids in Crude and Wine-Processed Rhizoma Coptidis by HPLC-PAD . Journal of chromatographic science, 2015, vol. 53, no. 1, p. 73-78. DOI
5. Liu, Xi., Xing, Rongrong., Chen, Xuan., Hu, Shuang., Sheng, Xia., Bai, Xiaohong. DETERMINATION OF PROTOBERBERINE ALKALOIDS IN COPTIS CHINENSIS BY MICROEXTRACTION AND HIGH PERFORMANCE LIQUID CHROMATOGRAPHY . Analytical letters, 2014, vol. 47, no. 16, p. 2655-2664. DOI
6. Zhou, J., Ouedraogo, M., Qu, F., Duez, P. Potential genotoxicity of traditional Chinese medicinal plants and phytochemicals: An overview. Phytotherapy Research, 2013, vol. 27, no. 12, p. 1745-1755. DOI
7. Ge, Ai-hua., Bai, Yang., Li, Jin., Liu, Jiao., He, Jun., Liu, Er-wei., Zhang, Peng., Zhang, Bo-li., Gao, Xiu-mei., Chang, Yan-xu. An activity-integrated strategy involving ultra-high-performance liquid chromatography/quadrupole-time-of-flight mass spectrometry and fraction collector for rapid screening and characterization of the alpha-glucosidase inhibitors in Coptis chinensis Franch. (Huanglian) . Journal of pharmaceutical and biomedical analysis, 2014, vol. 100, p. 79-87. DOI
8. Hou, Yulan., Wu, Tingting., Liu, Yaru., Wang, Hua., Chen, Yingzhuang., Chen, Bo., Sun, Wenjian. Direct analysis of quaternary alkaloids by in situ reactive desorption corona beam ionization MS. Analyst (cambridge, united kingdom), 2014, vol. 139, no. 20, p. 5185-5191.

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