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Botanical species · safety record

Coptis deltoidea

The EFSA Compendium of Botanicals holds 29 constituent measurements for Coptis deltoidea. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Coptis deltoidea C.Y.Cheng & P.K.Hsiao

29Constituent measurements
0Safety records
7Cited sources
2Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 2 licensed products naming Coptis deltoidea as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

  • Dry

Source material stated

  • Coptis chinensis - Rhizome
  • Rhizome

What the records describe

Constituents measured

  • Berberine5
  • Coptisine5
  • Epiberberine4
  • Jatrorrhizine4
  • Palmatine4
  • Columbamine2
  • Alkaloids1
  • Alpha-selinene1
  • Beta-​selinene1
  • Magnoflorine1

Plant parts

  • Roots and other underground parts15
  • Unspecified11
  • Bark3

Preparations

  • Solvent extraction27
  • Drying (dehydration)2

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
AlkaloidsRoots and other underground partsSolvent extraction—Nuclear Magnetic Resonance (NMR)Resolve DOI
Alpha-selineneRoots and other underground partsDrying (dehydration)3.8 PercentGC-MSResolve DOI
BerberineRoots and other underground partsSolvent extraction76.11 Milligram/gramHPLC with standard detection methodsResolve DOI
BerberineRoots and other underground partsSolvent extraction40 Milligram/gramHPLC-DADResolve DOI
Beta-​selineneRoots and other underground partsDrying (dehydration)4 PercentGC-MSResolve DOI
ColumbamineRoots and other underground partsSolvent extraction2 Milligram/gramHPLC-DADResolve DOI
ColumbamineRoots and other underground partsSolvent extraction4.25 Milligram/gramHPLC with standard detection methodsResolve DOI
CoptisineRoots and other underground partsSolvent extraction12.5 Milligram/gramHPLC-DADResolve DOI
CoptisineRoots and other underground partsSolvent extraction25.95 Milligram/gramHPLC with standard detection methodsResolve DOI
EpiberberineRoots and other underground partsSolvent extraction8 Milligram/gramHPLC-DADResolve DOI
EpiberberineRoots and other underground partsSolvent extraction13.91 Milligram/gramHPLC with standard detection methodsResolve DOI
JatrorrhizineRoots and other underground partsSolvent extraction3.47 Milligram/gramHPLC with standard detection methodsResolve DOI
JatrorrhizineRoots and other underground partsSolvent extraction8 Milligram/gramHPLC-DADResolve DOI
MagnoflorineRoots and other underground partsSolvent extraction—Nuclear Magnetic Resonance (NMR)Resolve DOI
PalmatineRoots and other underground partsSolvent extraction5 Milligram/gramHPLC-DADResolve DOI
ProtoberberineUnspecifiedSolvent extraction—High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
BerberineUnspecifiedSolvent extraction≤ 90.37 Milligram/gramHPLC-DADNo resolvable identifier
BerberineUnspecifiedSolvent extraction≥ 57.38 Milligram/gramHPLC-DADNo resolvable identifier
BerberineBarkSolvent extraction0.7 Milligram/gramNuclear Magnetic Resonance (NMR)No resolvable identifier
CoptisineUnspecifiedSolvent extraction≤ 33.48 Milligram/gramHPLC-DADNo resolvable identifier
CoptisineUnspecifiedSolvent extraction≥ 20.4 Milligram/gramHPLC-DADNo resolvable identifier
CoptisineBarkSolvent extraction0.5 Milligram/gramNuclear Magnetic Resonance (NMR)No resolvable identifier
EpiberberineUnspecifiedSolvent extraction≤ 311.1 Milligram/gramHPLC-DADNo resolvable identifier
EpiberberineUnspecifiedSolvent extraction≥ 228.53 Milligram/gramHPLC-DADNo resolvable identifier
JatrorrhizineUnspecifiedSolvent extraction≥ 9.57 Milligram/gramHPLC-DADNo resolvable identifier
JatrorrhizineUnspecifiedSolvent extraction≤ 13.59 Milligram/gramHPLC-DADNo resolvable identifier
PalmatineUnspecifiedSolvent extraction≥ 34.43 Milligram/gramHPLC-DADNo resolvable identifier
PalmatineBarkSolvent extraction0.3 Milligram/gramNuclear Magnetic Resonance (NMR)No resolvable identifier
PalmatineUnspecifiedSolvent extraction≤ 57.76 Milligram/gramHPLC-DADNo resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Dou, Sheng-shan., Zhu, Shuang-lai., Dai, Wei-xing., Zhang, Wei-dong., Zhang, Yi., Liu, Run-hui. Qualitative and quantitative analysis for the quality control of Rhizoma Coptidis by HPLC-DAD and HPLC-ESI-MS. Chemical research in chinese universities, 2010, vol. 26, no. 5, p. 735-741.
  2. Lv, Xiumei., Li, Yan., Tang, Ce., Zhang, Yi., Zhang, Jing., Fan, Gang. Integration of HPLC-based fingerprint and quantitative analyses for differentiating botanical species and geographical growing origins of Rhizoma coptidis . Pharmaceutical biology, 2016, vol. 54, no. 12, p. 3264-3271. DOI
  3. Fan, Gang., Tao, Ling-hui., Yue, Qing-hong., Kuang, Ting-ting., Tang, Ce., Yang, Yong-dong., Luo, Wei-zao., Zhou, Xiang-dong., Zhang, Yi. Metabolic Discrimination of Rhizoma Coptidis from Different Species Using H-1 NMR Spectroscopy and Principal Component Analysis . Planta medica, 2012, vol. 78, no. 6, p. 641-648. DOI
  4. Gao, Xin., Yang, Xiuwei., Mitrevski, Blagoj S., Marriott, Philip J. Headspace solid-phase microextraction combined with GC x GC-TOFMS for the analysis of volatile compounds of Coptis species rhizomes . Journal of separation science, 2011, vol. 34, no. 10, p. 1157-1166. DOI
  5. Li, Chia-Ying., Tsai, Sung-I., Damu, Amooru G., Wu, Tian-Shung. A rapid and simple determination of protoberberine alkaloids in Rhizoma Coptidis by 1H NMR and its application for quality control of commercial prescriptions. Journal of pharmaceutical and biomedical analysis, 2009, vol. 49, no. 5, p. 1272-1276.
  6. Fan, Gang., Zhang, Meng Ying., Zhou, Xiang Dong., Lai, Xian Rong., Yue, Qing Hong., Tang, Ce., Luo, Wei Zao., Zhang, Yi. Quality evaluation and species differentiation of Rhizoma coptidis by using proton nuclear magnetic resonance spectroscopy. ANALYTICA CHIMICA ACTA, 2012, vol. 747, p. 76-83. DOI
  7. Liu, Lu., Wang, Zhi-Bin., Song, Yang., Yang, Jing., Wu, Li-Jun., Yang, Bing-You., Wang, Qiu-Hong., Wang, Li-Qian., Wang, Ru-Xuan., Yang, Chun-Juan. Simultaneous Determination of Eight Alkaloids in Rat Plasma by UHPLC-MS/MS after Oral Administration of Coptis deltoidea C. Y. Cheng et Hsiao and Coptis chinensis Franch. . Molecules (basel, switzerland), 2016, vol. 21, no. 7. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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