Botanical species · safety record
Corydalis cava
The EFSA Compendium of Botanicals holds 26 constituent measurements for Corydalis cava. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Corydalis cava (L.) Schweigg. & Körte
Also recorded as
Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.
Regulatory presence
Health Canada's Licensed Natural Health Products Database holds 2 licensed products naming Corydalis cava as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.
Extract types on licence
Source material stated
What the records describe
Constituents measured
- Isoquinoline alkaloids4
- Bulbocapnine2
- Canadine2
- Palmatine2
- Alkaloids1
- Allocryptopine1
- Aporphine alkaloids1
- Coptisine1
- Corydaline1
- Corydine1
Plant parts
- Roots and other underground parts19
- Unspecified7
Preparations
- Solvent extraction24
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Alkaloids | Roots and other underground parts | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Aporphine alkaloids | Unspecified | Solvent extraction | — | Chromatographic tests | Resolve DOI |
| Bulbocapnine | Roots and other underground parts | Solvent extraction | 5.94 Gram/100 gram | Capillary (Zone) Electrophoresis (CE or CZE) | Resolve DOI |
| Canadine | Roots and other underground parts | Solvent extraction | 5.41 Gram/100 gram | Capillary (Zone) Electrophoresis (CE or CZE) | Resolve DOI |
| Coptisine | Roots and other underground parts | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Corydaline | Roots and other underground parts | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Corytuberine | Unspecified | Solvent extraction | — | Chromatographic tests | Resolve DOI |
| Dehydroapocavidine | Roots and other underground parts | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Dehydrocorydaline | Roots and other underground parts | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Glaucine | Unspecified | Solvent extraction | — | Chromatographic tests | Resolve DOI |
| Isoapocavidine | Roots and other underground parts | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Isoquinoline alkaloids | Unspecified | — | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Isoquinoline alkaloids | Unspecified | Solvent extraction | — | Chromatographic tests | Resolve DOI |
| Palmatine | Roots and other underground parts | Solvent extraction | 0.27 Gram/100 gram | Capillary (Zone) Electrophoresis (CE or CZE) | Resolve DOI |
| Palmatine | Roots and other underground parts | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Protopine | Unspecified | Solvent extraction | — | Chromatographic tests | Resolve DOI |
| Scoulerine | Roots and other underground parts | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Stylopine | Unspecified | — | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Tetrahydropalmatin | Roots and other underground parts | Solvent extraction | 2.04 Gram/100 gram | Capillary (Zone) Electrophoresis (CE or CZE) | Resolve DOI |
| Allocryptopine | Roots and other underground parts | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | No resolvable identifier |
| Bulbocapnine | Roots and other underground parts | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | No resolvable identifier |
| Canadine | Roots and other underground parts | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | No resolvable identifier |
| Corydine | Roots and other underground parts | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | No resolvable identifier |
| Isoquinoline alkaloids | Roots and other underground parts | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | No resolvable identifier |
| Isoquinoline alkaloids | Roots and other underground parts | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | No resolvable identifier |
| Sinoacutine | Roots and other underground parts | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Novak, Zdenek., Chlebek, Jakub., Opletal, Lubomir., Jiros, Pavel., Macakova, Katerina., Kunes, Jiri., Cahlikova, Lucie. Corylucinine, a new Alkaloid from Corydalis cava (Fumariaceae), and its Cholinesterase Activity . Natural product communications, 2012, vol. 7, no. 7, p. 859-860.
- Sturm, Sonja., Seger, Christoph., Stuppner, Hermann. Analysis of Central European Corydalis species by nonaqueous capillary electrophoresis-electrospray ion trap mass spectrometry . Journal of chromatography a, 2007, vol. 1159, no. 1-2, p. 42-50. DOI
- Salminen, Kaisa A., Meyer, Achim., Jerabkova, Lenka., Korhonen, Laura E., Rahnasto, Minna., Juvonen, Risto O., Imming, Peter., Raunio, Hannu. Inhibition of human drug metabolizing cytochrome P450 enzymes by plant isoquinoline alkaloids. PHYTOMEDICINE, 2011, vol. 18, no. 6, p. 533-538. DOI
- Chlebek, Jakub., Macakova, Katerina., Cahlikova, Lucie., Kurfuerst, Milan., Kunes, Jiri., Opletal, Lubomir. Acetylcholinesterase and Butyrylcholinesterase Inhibitory Compounds from Corydalis cava (Fumariaceae) . Natural product communications, 2011, vol. 6, no. 5, p. 607-610.
- Halbsguth, C., Meissner, O., Haberlein, HH. Positive cooperation of protoberberine type 2 alkaloids from Corydalis cava on the GABA(A) binding site . Planta medica, 2003, vol. 69, no. 4, p. 305-309. DOI
- Meyer, Achim., Imming, Peter. Benzylisoquinoline Alkaloids from the Papaveraceae: The Heritage of Johannes Gadamer (1867-1928) . Journal of natural products, 2011, vol. 74, no. 11, p. 2482-2487. DOI
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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