Botanical species · safety record

Crotalaria sessiliflora

The EFSA Compendium of Botanicals holds 7 constituent measurements and 1 adverse-effect record for Crotalaria sessiliflora. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Crotalaria sessiliflora L.

7Constituent measurements
1Safety records
5Cited sources
0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

  • Isoflavones2
  • Hydroquinone1
  • Integerrimine1
  • Monocrotaline1
  • Pyrrolizidine alkaloids1
  • Trichodesmine1

Plant parts

  • Aerial part of plants4
  • Seed3
  • Unspecified1

Preparations

  • Solvent extraction6

Effect types

  • Endocrine1

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
IsoflavonesAerial part of plantsResolve DOI
IsoflavonesAerial part of plantsSolvent extractionHPLC with standard detection methodsResolve DOI
HydroquinoneAerial part of plantsSolvent extractionNuclear Magnetic Resonance (NMR)No resolvable identifier
IntegerrimineSeedSolvent extractionNuclear Magnetic Resonance (NMR)No resolvable identifier
MonocrotalineSeedSolvent extractionNuclear Magnetic Resonance (NMR)No resolvable identifier
Pyrrolizidine alkaloidsUnspecifiedNo resolvable identifier
TrichodesmineSeedSolvent extractionNuclear Magnetic Resonance (NMR)No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

EffectTarget tissuePlant partPreparationTest organismTest typeSource
EndocrineAerial part of plantsSolvent extractionIn vitroResolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Yoo, HS., Lee, JS., Kim, CY., Kim, J. Flavonoids of Crotalaria sessiliflora. ARCHIVES OF PHARMACAL RESEARCH, 2004, vol. 27, no. 5, p. 544-546. DOI
  2. Lin, Ge., Li, Na., Li, Mi., Chan, Wood-Yee., Fu, Peter P., Xu, Hong-Xi. Potential biomarker for the assessment of hepatotoxicity induced by metabolic activation of pyrrolizidine alkaloids. DRUG METABOLISM REVIEWS, 2010, vol. 42, p. 207-207.
  3. Roeder, E., Liang, X. T., Kabus, K. J. Pyrrolizidine alkaloids from the seeds of Crotalaria sessiliflora. Planta Medica, 1992.
  4. Mun'im, A., Isoda, H., Seki, M., Negishi, O., Ozawa, T. Estrogenic and acetylcholinesterase-enhancement activity of a new isoflavone, 7,2 ',4 '-trihydroxyisoflavone-4 '-O-beta-D-glucopyranoside from Crotalaria sessililflora. CYTOTECHNOLOGY, 2003, vol. 43, no. 1-3, p. 127-134. DOI
  5. Mun'im, A., Negishi, O., Ozawa, T. Antioxidative compounds from Crotalaria sessiliflora. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2003, vol. 67, no. 2, p. 410-414.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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