Botanical species · safety record

Croton lechleri

The EFSA Compendium of Botanicals holds 9 constituent measurements for Croton lechleri. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Croton lechleri Müll.Arg.

9Constituent measurements

0Safety records

6Cited sources

8Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 8 licensed products naming Croton lechleri as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Extract Type TBA
Fresh

Source material stated

Latex
Sap resin
Whole plant

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Alpha-calacorene	Bark	Essential oil	11.29 Percent	GC-MS (Q)	Resolve DOI
Beta-calacorene	Bark	Essential oil	4.34 Percent	GC-MS	Resolve DOI
Cadalene	Bark	Essential oil	2.12 Percent	GC-MS	Resolve DOI
Clerodane-type diterpenes	Bark	Sap	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Furan derivatives	Unspecified	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	Resolve DOI
Isoquinoline alkaloids	Aerial part of plants	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Lignans	Unspecified	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	Resolve DOI
Sinoacutine	Leaves	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	Resolve DOI
Taspine	Aerial part of plants	Sap	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Rossi, Damiano., Guerrini, Alessandra., Maietti, Silvia., Bruni, Renato., Paganetto, Guglielmo., Poli, Ferruccio., Scalvenzi, Laura., Radice, Matteo., Saro, Katia., Sacchetti, Gianni. Chemical fingerprinting and bioactivity of Amazonian Ecuador Croton lechleri Mull. Arg. (Euphorbiaceae) stem bark essential oil: A new functional food ingredient? . Food chemistry, 2011, vol. 126, no. 3, p. 837-848. DOI
Montopoli, Monica., Bertin, Riccardo., Chen, Zheng., Bolcato, Jenny., Caparrotta, Laura., Froldi, Guglielmina. Croton lechleri sap and isolated alkaloid taspine exhibit inhibition against human melanoma SK23 and colon cancer HT29 cell lines. JOURNAL OF ETHNOPHARMACOLOGY, 2012, vol. 144, no. 3, p. 747-753. DOI
Carlin, L., Vaisberg, AJ., Hammond, GB. Isolation of sinoacutine from the leaves of Croton lechleri. PLANTA MEDICA, 1996, vol. 62, no. 1, p. 90-91. DOI
PIETERS, L., DEBRUYNE, T., CLAEYS, M., VLIETINCK, A., CALOMME, M., VANDENBERGHE, D. ISOLATION OF A DIHYDROBENZOFURAN LIGNAN FROM SOUTH-AMERICAN DRAGONS BLOOD (CROTON SPP) AS AN INHIBITOR OF CELL-PROLIFERATION. JOURNAL OF NATURAL PRODUCTS, 1993, vol. 56, no. 6, p. 899-906. DOI
Milanowski, DJ., Winter, REK., Elvin-Lewis, MPF., Lewis, WH. Geographic disitribution of three alkaloid chemotypes of Croton lechleri. Journal of natural products, 2002, vol. 65, no. 6, p. 814-819. DOI
CAI, Y., CHEN, ZP., PHILLIPSON, JD. BIOLOGICAL AND CHEMICAL INVESTIGATION OF DRAGONS BLOOD FROM CROTON SPECIES OF SOUTH-AMERICA .2. DITERPENES FROM CROTON-LECHLERI . Phytochemistry, 1993, vol. 32, no. 3, p. 755-760. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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