Botanical species · safety record
Cucurbita pepo
The EFSA Compendium of Botanicals holds 10 constituent measurements for Cucurbita pepo. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Cucurbita pepo L.
Regulatory presence
Health Canada's Licensed Natural Health Products Database holds 637 licensed products naming Cucurbita pepo as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.
Extract types on licence
Source material stated
What the records describe
Constituents measured
- Secoisolarisiresinol2
- Alkaloids1
- Arctigenin1
- Lariciresinol1
- Lectins1
- Lignans1
- Matairesinol1
- Pinoresinol1
- Saponins1
Plant parts
- Seed7
- Fruit unspecified3
Preparations
- Solvent extraction8
- Powder2
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Alkaloids | Seed | Powder | — | Phytochemical screening | Resolve DOI |
| Saponins | Seed | Powder | — | Phytochemical screening | Resolve DOI |
| Arctigenin | Seed | Solvent extraction | — | Mass Spectroscopy and hyphenated methods without chromatography | No resolvable identifier |
| Lariciresinol | Fruit unspecified | Solvent extraction | 64 Microgram/100 gram | LC-MS | No resolvable identifier |
| Lectins | Seed | Solvent extraction | — | Chromatographic tests | No resolvable identifier |
| Lignans | Seed | Solvent extraction | — | Mass Spectroscopy and hyphenated methods without chromatography | No resolvable identifier |
| Matairesinol | Seed | Solvent extraction | — | Mass Spectroscopy and hyphenated methods without chromatography | No resolvable identifier |
| Pinoresinol | Fruit unspecified | Solvent extraction | 37 Microgram/100 gram | LC-MS | No resolvable identifier |
| Secoisolarisiresinol | Seed | Solvent extraction | — | Mass Spectroscopy and hyphenated methods without chromatography | No resolvable identifier |
| Secoisolarisiresinol | Fruit unspecified | Solvent extraction | 18 Microgram/100 gram | LC-MS | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Richter, Dagmar., Abarzua, Sibylle., Chrobak, Mareike., Vrekoussis, Thomas., Weissenbacher, Tobias., Kuhn, Christina., Schulze, Sandra., Kupka, Markus S., Friese, Klaus., Briese, Volker. Effects of Phytoestrogen Extracts Isolated from Pumpkin Seeds on Estradiol Production and ER/PR Expression in Breast Cancer and Trophoblast Tumor Cells. Nutrition and cancer, 2013, vol. 65, no. 5, p. 739-745.
- Milder, Ivon E. J., Arts, Ilja C. W., van de Putte, Betty., Venema, Dini P., Hollman, Peter C. H. Lignan contents of Dutch plant foods: A database including lariciresinol, pinoresinol, secoisolariciresinol and matairesinol. British journal of nutrition, 2005, vol. 93, no. 3, p. 393-402.
- Ojiako, O. A., Igwe, C. U. Nutritional and anti-nutritional compositions of Cleome rutidosperma, Lagenaria siceraria, and Cucurbita maxima seeds from Nigeria . Journal of medicinal food, 2007, vol. 10, no. 4, p. 735-738. DOI
- Sarkar, Subodh Kumar., Hossain, M. Tofazzal., Uddin, M. Belal., Absar, Nurul. Purification, characterization and physico-chemical properties of three galactose-specific lectins from pumpkin (Cucurbita maxima) seed kernels . Journal of the chinese chemical society, 2007, vol. 54, no. 6, p. 1433-1442.
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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