Botanical species · safety record
Cullen drupaceum
The EFSA Compendium of Botanicals holds 25 constituent measurements and 1 adverse-effect record for Cullen drupaceum. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Cullen drupaceum (Bunge) C.H.Stirt.
Also recorded as
Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.
Regulatory presence
No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.
What the records describe
Constituents measured
- Psoralen8
- Angelicin5
- Bakuchiol3
- Furanocoumarins3
- Coumarins2
- Drupacine2
- Daidzein1
- Drupanin1
Plant parts
- Fruit unspecified5
- Seed5
- Roots and other underground parts4
- Unspecified4
- Aerial part of plants3
- Live plants3
- Leaves2
Preparations
- Solvent extraction16
Effect types
- Neurotoxicity1
Target tissues
- Neurologic: central nervous system1
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Psoralen | Seed | Solvent extraction | 0.7 Percent | Classification not possible | Resolve DOI |
| Angelicin | Leaves | Solvent extraction | 0.03 Percent | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
| Angelicin | Seed | Solvent extraction | 0.52 Percent | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
| Angelicin | Fruit unspecified | — | — | — | No resolvable identifier |
| Angelicin | Roots and other underground parts | Solvent extraction | 0.18 Percent | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
| Angelicin | Live plants | Solvent extraction | — | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
| Bakuchiol | Unspecified | — | — | — | No resolvable identifier |
| Bakuchiol | Fruit unspecified | Solvent extraction | — | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
| Bakuchiol | Aerial part of plants | Solvent extraction | — | — | No resolvable identifier |
| Coumarins | Aerial part of plants | — | — | — | No resolvable identifier |
| Coumarins | Unspecified | — | — | — | No resolvable identifier |
| Daidzein | Roots and other underground parts | Solvent extraction | — | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
| Drupacine | Seed | — | — | — | No resolvable identifier |
| Drupacine | Fruit unspecified | Solvent extraction | 0.03 Percent | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
| Drupanin | Fruit unspecified | Solvent extraction | 0.035 Percent | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
| Furanocoumarins | Aerial part of plants | — | — | — | No resolvable identifier |
| Furanocoumarins | Live plants | Solvent extraction | < 1.36 Percent | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
| Furanocoumarins | Unspecified | — | — | — | No resolvable identifier |
| Psoralen | Roots and other underground parts | Solvent extraction | 0.17 Percent | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
| Psoralen | Seed | Solvent extraction | 0.4 Percent | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
| Psoralen | Unspecified | — | — | — | No resolvable identifier |
| Psoralen | Fruit unspecified | — | — | — | No resolvable identifier |
| Psoralen | Leaves | Solvent extraction | 0.03 Percent | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
| Psoralen | Roots and other underground parts | Solvent extraction | 4 Gram/kilogram | — | No resolvable identifier |
| Psoralen | Live plants | Solvent extraction | — | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
Recorded adverse effects
Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.
| Effect | Target tissue | Plant part | Preparation | Test organism | Test type | Source |
|---|---|---|---|---|---|---|
| Neurotoxicity | Neurologic: central nervous system | Seed | — | Pig (as animal) | Case report | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Arutyunyants, S. I., Baimuradov, T. B., Rogozhin, P. S. Instance of Psoralea poisoning of swine.. Veterinariya (Moscow, Russian Federation), 1972, vol. 49, no. 8, p. 95-6.
- Usmanov, B. Z., Abubakirov, N. K. Separate determination of furocoumarins of Psoralea drupaceae.. Khimiko-Farmatsevticheskii Zhurnal, 1967, vol. 1, no. 5, p. 42-6.
- Fedorin, G. F., Georgievskii, V. P., Komissarenko, N. F., Beletskii, Yu. N. Comparative content of psoralen and other furocoumarins in raw materials from Coronilla scorpioides, Psoralea drupacea, and Ficus carica.. Rastitel'nye Resursy, 1975, vol. 11, no. 3, p. 372-3.
- Smirnov, V. V., Romanenko, V. M., Prikhod'ko, V. A. Effect of bakuchiol on ultrastructure of Staphylococcus aureus 209 cells.. Mikrobiologicheskii Zhurnal (1978-1993), 1984, vol. 46, no. 5, p. 72-4.
- Shakirov, T.T., Kartashkina, I.N., Shamsutdinov, M.R.I. Technology of the extraction of psoralene from seeds of Psoralea drupacea BGE. Pharmaceutical chemistry journal, 1968, vol. 1, no. 4, p. 224-225. DOI
- Kurmukov, A. G., Akhmedkhodzhaeva, Kh. S., Sidyakin, V. G., Syrov, V. N. Phytoestrogens from plants of Central Asia.. Rastitel'nye Resursy, 1976, vol. 12, no. 4, p. 515-25.
- Golovina, L. A., Nikonov, G. K. The structure of drupanol - A new phenol of Psoralea drupaceae.. Chemistry of Natural Compounds 1973, vol. 9, no. 1, p. 7-9.
- Nikonov, G. K., Artamonova, N. A. Phenolic components of the nonsaponifiable fraction of Psoralea drupacea.. Khimiya Prirodnykh Soedinenii, 1993, no. 2, p. 300-1.
- Karryev, M. O., Komissarenko, N. F. Furocoumarin-containing vegetation of Turkmen SSR.. Izvestiya Akademii Nauk Turkmenskoi SSR, Seriya Biologicheskikh Nauk, 1981, no. 1, p. 65-9.
- Yuldashev, M. P., Batirov, E. Kh., Malikov, V. M., Yuldasheva, N. P. Flavonoids of Psoralea drupaceae and Reseda luteola.. Khimiya prirodnykh soedinenii, 1996, no. 6, p. 949-951.
- Golovina, L. A., Nikonov, G. K. Structure of drupacine and drupanine, new components of Psoralea drupaceae.. Khimiya Prirodnykh Soedinenii, 1973, no. 6, p. 700-3.
- Abubakirov, N. K., Khalmurzaev, U. F. Furocoumarins of Psoralea drupacea.. Chemistry of Natural Compounds, 1967, vol. 3, no. 2, p. 137-8.
- Kartashkina, I. N., Shamsutdinov, R. I., Shakirov, T. T. Method of isolating psoralen from roots of Psoralea drupacea.. Meditsinskaya Promyshlennost SSSR, 1966, vol. 20, no. 5, p. 38-40.
- Bondarenko, A. S., Aizenman, B. E., Zatula, D. G., Bakina, L. A., Kozhina, I. S., Prikhod'ko, V. A., Silkina, O. V., Meshcheryakov, A. A. Psoralea drupacea Bunge as a promising source of the antibiotic Bakuchiol.. Rastitel'nye Resursy, 1977, vol. 13, no. 3, p. 460-3.
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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