Botanical species · safety record

Cullen drupaceum

The EFSA Compendium of Botanicals holds 25 constituent measurements and 1 adverse-effect record for Cullen drupaceum. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Cullen drupaceum (Bunge) C.H.Stirt.

25Constituent measurements
1Safety records
14Cited sources
0Licensed products (Canada)

Also recorded as

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

  • Psoralen8
  • Angelicin5
  • Bakuchiol3
  • Furanocoumarins3
  • Coumarins2
  • Drupacine2
  • Daidzein1
  • Drupanin1

Plant parts

  • Fruit unspecified5
  • Seed5
  • Roots and other underground parts4
  • Unspecified4
  • Aerial part of plants3
  • Live plants3
  • Leaves2

Preparations

  • Solvent extraction16

Effect types

  • Neurotoxicity1

Target tissues

  • Neurologic: central nervous system1

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
PsoralenSeedSolvent extraction0.7 PercentClassification not possibleResolve DOI
AngelicinLeavesSolvent extraction0.03 PercentStandard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier
AngelicinSeedSolvent extraction0.52 PercentStandard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier
AngelicinFruit unspecifiedNo resolvable identifier
AngelicinRoots and other underground partsSolvent extraction0.18 PercentStandard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier
AngelicinLive plantsSolvent extractionStandard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier
BakuchiolUnspecifiedNo resolvable identifier
BakuchiolFruit unspecifiedSolvent extractionStandard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier
BakuchiolAerial part of plantsSolvent extractionNo resolvable identifier
CoumarinsAerial part of plantsNo resolvable identifier
CoumarinsUnspecifiedNo resolvable identifier
DaidzeinRoots and other underground partsSolvent extractionStandard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier
DrupacineSeedNo resolvable identifier
DrupacineFruit unspecifiedSolvent extraction0.03 PercentStandard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier
DrupaninFruit unspecifiedSolvent extraction0.035 PercentStandard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier
FuranocoumarinsAerial part of plantsNo resolvable identifier
FuranocoumarinsLive plantsSolvent extraction< 1.36 PercentStandard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier
FuranocoumarinsUnspecifiedNo resolvable identifier
PsoralenRoots and other underground partsSolvent extraction0.17 PercentStandard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier
PsoralenSeedSolvent extraction0.4 PercentStandard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier
PsoralenUnspecifiedNo resolvable identifier
PsoralenFruit unspecifiedNo resolvable identifier
PsoralenLeavesSolvent extraction0.03 PercentStandard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier
PsoralenRoots and other underground partsSolvent extraction4 Gram/kilogramNo resolvable identifier
PsoralenLive plantsSolvent extractionStandard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

EffectTarget tissuePlant partPreparationTest organismTest typeSource
NeurotoxicityNeurologic: central nervous systemSeedPig (as animal)Case reportNo resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Arutyunyants, S. I., Baimuradov, T. B., Rogozhin, P. S. Instance of Psoralea poisoning of swine.. Veterinariya (Moscow, Russian Federation), 1972, vol. 49, no. 8, p. 95-6.
  2. Usmanov, B. Z., Abubakirov, N. K. Separate determination of furocoumarins of Psoralea drupaceae.. Khimiko-Farmatsevticheskii Zhurnal, 1967, vol. 1, no. 5, p. 42-6.
  3. Fedorin, G. F., Georgievskii, V. P., Komissarenko, N. F., Beletskii, Yu. N. Comparative content of psoralen and other furocoumarins in raw materials from Coronilla scorpioides, Psoralea drupacea, and Ficus carica.. Rastitel'nye Resursy, 1975, vol. 11, no. 3, p. 372-3.
  4. Smirnov, V. V., Romanenko, V. M., Prikhod'ko, V. A. Effect of bakuchiol on ultrastructure of Staphylococcus aureus 209 cells.. Mikrobiologicheskii Zhurnal (1978-1993), 1984, vol. 46, no. 5, p. 72-4.
  5. Shakirov, T.T., Kartashkina, I.N., Shamsutdinov, M.R.I. Technology of the extraction of psoralene from seeds of Psoralea drupacea BGE. Pharmaceutical chemistry journal, 1968, vol. 1, no. 4, p. 224-225. DOI
  6. Kurmukov, A. G., Akhmedkhodzhaeva, Kh. S., Sidyakin, V. G., Syrov, V. N. Phytoestrogens from plants of Central Asia.. Rastitel'nye Resursy, 1976, vol. 12, no. 4, p. 515-25.
  7. Golovina, L. A., Nikonov, G. K. The structure of drupanol - A new phenol of Psoralea drupaceae.. Chemistry of Natural Compounds 1973, vol. 9, no. 1, p. 7-9.
  8. Nikonov, G. K., Artamonova, N. A. Phenolic components of the nonsaponifiable fraction of Psoralea drupacea.. Khimiya Prirodnykh Soedinenii, 1993, no. 2, p. 300-1.
  9. Karryev, M. O., Komissarenko, N. F. Furocoumarin-containing vegetation of Turkmen SSR.. Izvestiya Akademii Nauk Turkmenskoi SSR, Seriya Biologicheskikh Nauk, 1981, no. 1, p. 65-9.
  10. Yuldashev, M. P., Batirov, E. Kh., Malikov, V. M., Yuldasheva, N. P. Flavonoids of Psoralea drupaceae and Reseda luteola.. Khimiya prirodnykh soedinenii, 1996, no. 6, p. 949-951.
  11. Golovina, L. A., Nikonov, G. K. Structure of drupacine and drupanine, new components of Psoralea drupaceae.. Khimiya Prirodnykh Soedinenii, 1973, no. 6, p. 700-3.
  12. Abubakirov, N. K., Khalmurzaev, U. F. Furocoumarins of Psoralea drupacea.. Chemistry of Natural Compounds, 1967, vol. 3, no. 2, p. 137-8.
  13. Kartashkina, I. N., Shamsutdinov, R. I., Shakirov, T. T. Method of isolating psoralen from roots of Psoralea drupacea.. Meditsinskaya Promyshlennost SSSR, 1966, vol. 20, no. 5, p. 38-40.
  14. Bondarenko, A. S., Aizenman, B. E., Zatula, D. G., Bakina, L. A., Kozhina, I. S., Prikhod'ko, V. A., Silkina, O. V., Meshcheryakov, A. A. Psoralea drupacea Bunge as a promising source of the antibiotic Bakuchiol.. Rastitel'nye Resursy, 1977, vol. 13, no. 3, p. 460-3.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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