Botanical species · safety record

Cuminum cyminum

The EFSA Compendium of Botanicals holds 14 constituent measurements and 4 adverse-effect records for Cuminum cyminum. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Cuminum cyminum L.

14Constituent measurements

4Safety records

6Cited sources

63Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 63 licensed products naming Cuminum cyminum as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Source material stated

Fruit
Grain(s)
New material
Seed
Seed(s)

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Myrcene	Seed	Essential oil	3.79 Percent	GC-MS	Resolve DOI
Alkaloids	Seed	Solvent extraction	286 Microgram/kilogram	Mass Spectroscopy and hyphenated methods without chromatography	No resolvable identifier
Alkaloids	Seed	Solvent extraction	233 Microgram/kilogram	Mass Spectroscopy and hyphenated methods without chromatography	No resolvable identifier
Alkaloids	Seed	Solvent extraction	< 2 Microgram/kilogram	Mass Spectroscopy and hyphenated methods without chromatography	No resolvable identifier
Alkaloids	Seed	Solvent extraction	13 Microgram/kilogram	Mass Spectroscopy and hyphenated methods without chromatography	No resolvable identifier
Furanocoumarins	Seed	Solvent extraction	≥ 7.7 Nanogram/gram	Mass Spectroscopy and hyphenated methods without chromatography	No resolvable identifier
Furanocoumarins	Seed	Solvent extraction	≤ 8.7 Nanogram/gram	Mass Spectroscopy and hyphenated methods without chromatography	No resolvable identifier
Harmaline	Seed	Solvent extraction	< 6 Microgram/kilogram	Mass Spectroscopy and hyphenated methods without chromatography	No resolvable identifier
Indole alkaloids	Seed	Solvent extraction	—	Mass Spectroscopy and hyphenated methods without chromatography	No resolvable identifier
Piperidine alkaloids	Seed	Solvent extraction	—	Mass Spectroscopy and hyphenated methods without chromatography	No resolvable identifier
Pyrrolizidine alkaloids	Seed	Solvent extraction	—	Mass Spectroscopy and hyphenated methods without chromatography	No resolvable identifier
Quinidine	Seed	Solvent extraction	—	Mass Spectroscopy and hyphenated methods without chromatography	No resolvable identifier
Quinine	Seed	Solvent extraction	—	Mass Spectroscopy and hyphenated methods without chromatography	No resolvable identifier
Theobromine	Seed	Solvent extraction	< 4.5 Microgram/kilogram	Mass Spectroscopy and hyphenated methods without chromatography	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
None	—	Unspecified	Essential oil (as part-nature)	Rat (as animal)	Short-term toxicity	Resolve DOI
Other toxicities	Skin/subcutis	Seed	—	House mouse (as animal)	Chronic/long term toxicity	Resolve DOI
Reproductive	—	Seed	Solvent extraction	Rat (as animal)	Short-term toxicity	No resolvable identifier
Reproductive	—	Seed	Solvent extraction	Rat (as animal)	Short-term toxicity	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Taghizadeh, Mohsen., Ostad, Seyed Naser., Asemi, Zatollah., Mahboubi, Mohaddese., Hejazi, Sara., Sharafati-Chaleshtori, Reza., Rashidi, Aliakbar., Akbari, Hosein., Sharifi, Nasrin. Sub-chronic oral toxicity of Cuminum cyminum L.'s essential oil in female Wistar rats . Regulatory toxicology and pharmacology, 2017, vol. 88, p. 138-143. DOI
Shah, A.H., Qureshi, S., Tariq, M., Ageel, A.M. Toxicity studies on six plants used in the traditional Arab system of medicine. Phytotherapy research, 1989, vol. 3, no. 1, p. 25-29. DOI
Nardin, Tiziana., Piasentier, Edi., Barnaba, Chiara., Larcher, Roberto. Alkaloid profiling of herbal drugs using high resolution mass spectrometry. Drug testing and analysis, 2017, p. Ahead of Print.
Al-Khamis, K.I., Al-Said, M.A., Islam, M.W., Tariq, M., Parmar, N.S., Ageel, A.M. Antifertility, anti-implantation and abortifacient activity of the aqueous extract of Cuminum cyminum. Fitoterapia, 1988, vol. 59, no. 1, p. 5-9.
Melough, Melissa M., Lee, Sang Gil., Cho, Eunyoung., Kim, Kijoon., Provatas, Anthony A., Perkins, Christopher., Park, Min Kyung., Qureshi, Abrar., Chun, Ock K. Identification and Quantitation of Furocoumarins in Popularly Consumed Foods in the U.S. Using QuEChERS Extraction Coupled with UPLC-MS/MS Analysis. Journal of agricultural and food chemistry, 2017, vol. 65, no. 24, p. 5049-5055.
Martinez-Velazquez, Moises., Adolfo Castillo-Herrera, Gustavo., Rosario-Cruz, Rodrigo., Miguel Flores-Fernandez, Jose., Lopez-Ramirez, Julisa., Hernandez-Gutierrez, Rodolfo., del Carmen Lugo-Cervantes, Eugenia. Acaricidal effect and chemical composition of essential oils extracted from Cuminum cyminum, Pimenta dioica and Ocimum basilicum against the cattle tick Rhipicephalus (Boophilus) microplus (Acari: Ixodidae) . Parasitology research, 2011, vol. 108, no. 2, p. 481-487. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature