Botanical species · safety record

Curculigo orchioides

The EFSA Compendium of Botanicals holds 11 constituent measurements and 1 adverse-effect record for Curculigo orchioides. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Curculigo orchioides Gaertn.

11Constituent measurements
1Safety records
8Cited sources
114Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 114 licensed products naming Curculigo orchioides as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

  • Dry
  • Extract Type TBA
  • decoction

Source material stated

  • New material
  • Rhizoma
  • Rhizome
  • Rhizome(s)
  • Root
  • Root and Rhizome
  • Root and rhizome
  • Root extract

What the records describe

Constituents measured

  • Lignans2
  • Saponins2
  • Calcium oxalate1
  • Cardiac glycosides1
  • Coumarins1
  • Gallic acid1
  • Lycorine1
  • Pregnane derivatives1
  • Tannins1

Plant parts

  • Roots and other underground parts12

Preparations

  • Solvent extraction11

Effect types

  • Reproductive1

Target tissues

  • Uterus1

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
Cardiac glycosidesRoots and other underground partsSolvent extractionPhytochemical screeningResolve DOI
CoumarinsRoots and other underground partsSolvent extractionPhytochemical screeningResolve DOI
LignansRoots and other underground partsSolvent extractionUHPLC-MS-MSResolve DOI
LignansRoots and other underground partsSolvent extractionPhytochemical screeningResolve DOI
Pregnane derivativesRoots and other underground partsSolvent extractionChromatographic testsResolve DOI
SaponinsRoots and other underground partsSolvent extractionGelpermeation, High Performance Thin Layer Chromatography (HPTLC)Resolve DOI
SaponinsRoots and other underground partsSolvent extractionPhytochemical screeningResolve DOI
TanninsRoots and other underground partsSolvent extractionPhytochemical screeningResolve DOI
Calcium oxalateRoots and other underground partsSolvent extractionHistometrical standard testsNo resolvable identifier
Gallic acidRoots and other underground partsSolvent extraction3.54 PercentGelpermeation, High Performance Thin Layer Chromatography (HPTLC)No resolvable identifier
LycorineRoots and other underground partsSolvent extractionPhytochemical screeningNo resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

EffectTarget tissuePlant partPreparationTest organismTest typeSource
ReproductiveUterusRoots and other underground partsHuman (as organism)Reproduction toxicityNo resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Patil, A., Koli, S., Patil, D.A., Narayane, V., Phatak, A.V. Evaluation of effect of aqueous slurry of curculigo orchioides Gaertn. rhizome in streptozotocin-induced diabetic rats. Journal of Pharmacy Research, 2013, vol. 7, no. 8, p. 747-753. DOI
  2. Shrikumar, S., Athem, M., Sukumar, M., Ravi, T.K. A HPTLC method for standardization of Curculigo orchioides rhizomes and its marketed formulation using gallic acid as standard. Indian journal of pharmaceutical sciences, 2005, vol. 67, no. 6, p. 721-724.
  3. He, Yongjing., Dong, Xin., Jia, Xiaoxuan., Li, Mei., Yuan, Tingting., Xu, Hongtao., Qin, Luping., Han, Ting., Zhang, Qiaoyan. Qualitative and quantitative analysis on chemical constituents from Curculigo orchioides using ultra high performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry . Journal of pharmaceutical and biomedical analysis, 2015, vol. 102, p. 236-245. DOI
  4. Asif, M. A review on phytochemical and ethnopharmacological activities of Curculigo orchioides. Mahidol University Journal of Pharmaceutical Sciences, 2012, p. 1-10.
  5. Ajesh, T.P., Krishnaraj, M.V., Prabu, M., Kumuthakalavalli, R. Herbal abortifacients used by Mannan tribes of Kerala, India. International Journal of PharmTech Research, 2012, vol. 4, no. 3, p. 1015-1017.
  6. Patil, A.G., Koli, S.P., Patil, D.A., Phatak, A.V., Chandra, N. Pharmacognostic evaluation and hptlc fingerprint profile of Curculigo orchioides Gaertn. Rhizomes. International Journal of Pharma and Bio Sciences, 2012, vol. 3, no. 3, p. P101-P111.
  7. XU, JP., XU, RS. CYCLOARTANE-TYPE SAPOGENINS AND THEIR GLYCOSIDES FROM CURCULIGO-ORCHIOIDES. PHYTOCHEMISTRY, 1992, vol. 31, no. 7, p. 2455-2458. DOI
  8. Jiao, Wei., Chen, Xiaozhen., Wang, Haibo., Lu, Runhua., Shao, Huawu. A new hepatotoxic triterpenoid ketone from Curculigo orchioides. FITOTERAPIA, 2013, vol. 84, p. 1-5. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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