Botanical species · safety record
Curculigo orchioides
The EFSA Compendium of Botanicals holds 11 constituent measurements and 1 adverse-effect record for Curculigo orchioides. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Curculigo orchioides Gaertn.
Regulatory presence
Health Canada's Licensed Natural Health Products Database holds 114 licensed products naming Curculigo orchioides as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.
Extract types on licence
Source material stated
What the records describe
Constituents measured
- Lignans2
- Saponins2
- Calcium oxalate1
- Cardiac glycosides1
- Coumarins1
- Gallic acid1
- Lycorine1
- Pregnane derivatives1
- Tannins1
Plant parts
- Roots and other underground parts12
Preparations
- Solvent extraction11
Effect types
- Reproductive1
Target tissues
- Uterus1
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Cardiac glycosides | Roots and other underground parts | Solvent extraction | — | Phytochemical screening | Resolve DOI |
| Coumarins | Roots and other underground parts | Solvent extraction | — | Phytochemical screening | Resolve DOI |
| Lignans | Roots and other underground parts | Solvent extraction | — | UHPLC-MS-MS | Resolve DOI |
| Lignans | Roots and other underground parts | Solvent extraction | — | Phytochemical screening | Resolve DOI |
| Pregnane derivatives | Roots and other underground parts | Solvent extraction | — | Chromatographic tests | Resolve DOI |
| Saponins | Roots and other underground parts | Solvent extraction | — | Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) | Resolve DOI |
| Saponins | Roots and other underground parts | Solvent extraction | — | Phytochemical screening | Resolve DOI |
| Tannins | Roots and other underground parts | Solvent extraction | — | Phytochemical screening | Resolve DOI |
| Calcium oxalate | Roots and other underground parts | Solvent extraction | — | Histometrical standard tests | No resolvable identifier |
| Gallic acid | Roots and other underground parts | Solvent extraction | 3.54 Percent | Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) | No resolvable identifier |
| Lycorine | Roots and other underground parts | Solvent extraction | — | Phytochemical screening | No resolvable identifier |
Recorded adverse effects
Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.
| Effect | Target tissue | Plant part | Preparation | Test organism | Test type | Source |
|---|---|---|---|---|---|---|
| Reproductive | Uterus | Roots and other underground parts | — | Human (as organism) | Reproduction toxicity | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Patil, A., Koli, S., Patil, D.A., Narayane, V., Phatak, A.V. Evaluation of effect of aqueous slurry of curculigo orchioides Gaertn. rhizome in streptozotocin-induced diabetic rats. Journal of Pharmacy Research, 2013, vol. 7, no. 8, p. 747-753. DOI
- Shrikumar, S., Athem, M., Sukumar, M., Ravi, T.K. A HPTLC method for standardization of Curculigo orchioides rhizomes and its marketed formulation using gallic acid as standard. Indian journal of pharmaceutical sciences, 2005, vol. 67, no. 6, p. 721-724.
- He, Yongjing., Dong, Xin., Jia, Xiaoxuan., Li, Mei., Yuan, Tingting., Xu, Hongtao., Qin, Luping., Han, Ting., Zhang, Qiaoyan. Qualitative and quantitative analysis on chemical constituents from Curculigo orchioides using ultra high performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry . Journal of pharmaceutical and biomedical analysis, 2015, vol. 102, p. 236-245. DOI
- Asif, M. A review on phytochemical and ethnopharmacological activities of Curculigo orchioides. Mahidol University Journal of Pharmaceutical Sciences, 2012, p. 1-10.
- Ajesh, T.P., Krishnaraj, M.V., Prabu, M., Kumuthakalavalli, R. Herbal abortifacients used by Mannan tribes of Kerala, India. International Journal of PharmTech Research, 2012, vol. 4, no. 3, p. 1015-1017.
- Patil, A.G., Koli, S.P., Patil, D.A., Phatak, A.V., Chandra, N. Pharmacognostic evaluation and hptlc fingerprint profile of Curculigo orchioides Gaertn. Rhizomes. International Journal of Pharma and Bio Sciences, 2012, vol. 3, no. 3, p. P101-P111.
- XU, JP., XU, RS. CYCLOARTANE-TYPE SAPOGENINS AND THEIR GLYCOSIDES FROM CURCULIGO-ORCHIOIDES. PHYTOCHEMISTRY, 1992, vol. 31, no. 7, p. 2455-2458. DOI
- Jiao, Wei., Chen, Xiaozhen., Wang, Haibo., Lu, Runhua., Shao, Huawu. A new hepatotoxic triterpenoid ketone from Curculigo orchioides. FITOTERAPIA, 2013, vol. 84, p. 1-5. DOI
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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