Botanical species · safety record
Curcuma longa
The EFSA Compendium of Botanicals holds 3 genotoxicity assays for Curcuma longa. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Curcuma longa L.
Regulatory presence
Health Canada's Licensed Natural Health Products Database holds 3,137 licensed products naming Curcuma longa as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.
Extract types on licence
Source material stated
Genotoxicity testing
Outcomes of genotoxicity assays as recorded in the source. A negative assay is a result under those test conditions, not a clearance.
| Outcome | Endpoint | Test | Tested organism | Metabolic activation | Source |
|---|---|---|---|---|---|
| Positive | DNA damage and/or repair | in vitro mammalian cell micronucleus test | Human (as organism) | — | Resolve DOI |
| Positive | gene mutation | bacterial gene mutation assay | Salmonella typhimurium (as organism) | With | No resolvable identifier |
| Positive | chromosome aberration | chromosome aberration assay | Rat (as animal) | — | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Cao, J., Jiang, L.-P., Liu, Y., Yang, G., Yao, X.-F., Zhong, L.-F. Curcumin-induced genotoxicity and antigenotoxicity in HepG2 cells. Toxicon, 2007, vol. 49, no. 8, p. 1219-1222. DOI
- Park, H.-J. Mutagenicity of the essential oils in Ames Test. Korean journal of pharmacognosy, 2002, vol. 33, no. 4, p. 372-375.
- Hassanane, M. M., Ahmed, E. S., Shoman, Th. M., Ezz-Eldin, A. Evaluation of the genotoxicity and antigenotoxicity of curcumin by chromosomal aberrations and biochemical studies in the albino rats exposed to methotrexate. Global veterinaria, 2010, p. 185-189.
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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