Botanical species · safety record

Cyclea peltata

The EFSA Compendium of Botanicals holds 25 constituent measurements and 4 adverse-effect records for Cyclea peltata. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Cyclea peltata (Lam.) Hook.f. & Thomson

25Constituent measurements

4Safety records

9Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Alkaloids	Roots and other underground parts	Solvent extraction	—	Phytochemical screening	Resolve DOI
Bisbenzylisoquinoline alkaloids	Roots and other underground parts	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Cycleapeltine	Roots and other underground parts	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Diterpenes	Roots and other underground parts	Solvent extraction	—	Phytochemical screening	Resolve DOI
Saponins	Roots and other underground parts	Solvent extraction	—	Phytochemical screening	Resolve DOI
Tannins	Roots and other underground parts	Solvent extraction	—	Phytochemical screening	Resolve DOI
Tetrandrine	Roots and other underground parts	Solvent extraction	—	HPLC with standard detection methods	Resolve DOI
1-bebeerine	Unspecified	—	—	Unspecified	No resolvable identifier
Alkaloids	Leaves	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Alkaloids	Roots and other underground parts	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Berbamine	Unspecified	—	—	—	No resolvable identifier
Cycleahomine	Roots and other underground parts	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Cycleanine	Unspecified	—	—	—	No resolvable identifier
Cycleapeltine	Roots and other underground parts	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
D-isochondodendrine	Unspecified	—	—	Unspecified	No resolvable identifier
D-isochondodendrine	Roots and other underground parts	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	No resolvable identifier
Fangchinoline	Roots and other underground parts	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	No resolvable identifier
Fangchinoline	Roots and other underground parts	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Magnoflorine	Unspecified	—	—	—	No resolvable identifier
N'-nor-d-tetrandrine	Unspecified	—	—	—	No resolvable identifier
N'-nor-d-tetrandrine	Roots and other underground parts	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Saponins	Leaves	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Tannins	Leaves	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Tetrandrine	Roots and other underground parts	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	No resolvable identifier
Tetrandrine	Unspecified	—	—	—	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Neurotoxicity	Muscle, skeletal	Roots and other underground parts	Solvent extraction	House mouse (as animal)	Not reported	No resolvable identifier
Other toxicities	Urogenital: urinary bladder	Roots and other underground parts	Solvent extraction	Rat (as animal)	Other	No resolvable identifier
Not stated	Digestive	Roots and other underground parts	Drying (dehydration)	Rat (as animal)	Other	No resolvable identifier
Not stated	Digestive	Live plants	Solvent extraction	Rat (as animal)	Short-term toxicity	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Kirana, H., Srinivasan, B. P. Effect of Cyclea peltata Lam. roots aqueous extract on glucose levels, lipid profile, insulin, TNF-alpha and skeletal muscle glycogen in type 2 diabetic rats. INDIAN JOURNAL OF EXPERIMENTAL BIOLOGY, 2010, vol. 48, no. 5, p. 499-502.
Kupchan, S. Morris., Yokoyama, Naokata., Thyagarajan, B. S. Menispermaceae alkaloids. II. The alkaloids of Cyclea peltata. Journal of Pharmaceutical Sciences, 1961, p. 164-167.
An, Yinling., Zhang, Xin., Hu, Wangyun. Chemical constituents from Cyclea peltata. Tianran Chanwu Yanjiu Yu Kaifa, 1999, p. 27-30.
Hullatti, K K., Gopikrishna, U V., Kuppast, I J. Phytochemical investigation and diuretic activity of Cyclea peltata leaf extracts.. Journal of advanced pharmaceutical technology & research, 2011, vol. 2, no. 4, p. 241-4. DOI
Pillai, R., Gray, A.I., Uma, V.S. Targeted isolation of alkaloid from Cyclea Peltata and determination of structural formula of Tetrandrine alkaloid based on NMR studies. International journal of phytomedicine, 2010, vol. 2, no. 4, p. 392-401. DOI
Kupchan, S.M., Liepa, A.J., Baxter, R.L., Hintz, H.P.J. New alkaloids and related artifacts from Cyclea peltata. Journal of Organic Chemistry, 1973, vol. 38, no. 10, p. 1846-1852.
Sangeetha, M.S., Priyanga, S., Hemmalakshmi, S., Devaki, K. In vivo antidiabetic potential of Cyclea Peltata in streptozotocin-induced-diabetic rats. Asian Journal of Pharmaceutical and Clinical Research, 2015, vol. 8, no. 1, p. 103-108.
Shri Vijaya Kirubha, T., Senthamarai, R., Mariya, P., Mani, P. Pharmacognostical and phytochemical standards of Cyclea peltata. (Lam) Hook.f & Thomson leaves. Journal of Chemical and Pharmaceutical Research, 2012, vol. 4, no. 3, p. 1465-1469.
Hullatti, K. K., Sharada, M. S., Kuppasth, I. J. Studies on diuretic activity of three plants from Menispermaceae family. Pharmacia Sinica, 2011, p. 129-134.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature