Botanical species · safety record

Cyclocarya paliurus

The EFSA Compendium of Botanicals holds 11 constituent measurements and 1 adverse-effect record for Cyclocarya paliurus. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Cyclocarya paliurus (Batalin) Iljinsk.

11Constituent measurements

1Safety records

8Cited sources

3Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 3 licensed products naming Cyclocarya paliurus as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Source material stated

Leaf

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Sesquiterpene lactones	Leaves	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Triterpene saponins	Leaves	—	—	Unspecified	Resolve DOI
Bergenin	Leaves	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Coumarins	Leaves	—	≤ 6.63 Percent	Unspecified	No resolvable identifier
Coumarins	Leaves	—	≥ 4.23 Percent	Unspecified	No resolvable identifier
Gallic acid	Leaves	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	No resolvable identifier
Saponins	Aerial part of plants	Solvent extraction	≥ 2.59 Percent	Unspecified	No resolvable identifier
Saponins	Leaves	—	≤ 10.99 Percent	Unspecified	No resolvable identifier
Saponins	Leaves	—	≥ 9.83 Percent	Unspecified	No resolvable identifier
Saponins	Aerial part of plants	Solvent extraction	≤ 6.52 Percent	Unspecified	No resolvable identifier
Triterpene saponins	Aerial part of plants	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Digestive	Digestive	Aerial part of plants	—	House mouse (as animal)	Short-term toxicity	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Kurihara, H., Fukami, H., Kusumoto, A., Toyoda, Y., Shibata, H., Matsui, Y., Asami, S., Tanaka, T. Hypoglycemic action of Cyclocarya paliurus (Batal.) Iljinskaja in normal and diabetic mice . Bioscience biotechnology and biochemistry, 2003, vol. 67, no. 4, p. 877-880.
Zhang, Juan., Lu, Jin-cai., Xiao, Kai., Lu, Ting., Fan, Jun-wen., Zhang, Li-ming., Zhao, Jie., Yang, Jian-jun. Study on water-soluble constituents in leaves of Cyclocarya paliurus. Yaoxue shijian zazhi, 2007, p. 82-84.
Chen, Jinhua., Huang, Jianan., Liu, Zhonghua. Analysis on chemical constituents in the leaves of Cyclocarya Paliurus. Shipin gongye keji, 2009, p. 159-160.
Shu, Rengeng., Shu, Jicheng. Phenols of Cyclocarya paliurus. Zhongcaoyao, 2007, p. 507-508.
Jiang, Xiang-hui., Yuan, Jing., Zhu, Jun-wei., Hu, Xiu-hong., Peng, Yi. Effect of post-harvest processing and extraction methods on total saponin content of Cyclocarya paliurus. Beifang yuanyi, 2014, p. 120-123.
Li, Jun., Lu, Yuanyuan., Su, Xiaojian., Li, Fu., She, Zhigang., He, Xingcun., Lin, Yongcheng. A norsesquiterpene lactone and a benzoic acid derivative from the leaves of cyclocarya paliurus and their glucosidase and glycogen phosphorylase inhibiting activites. PLANTA MEDICA, 2008, vol. 74, no. 3, p. 287-289. DOI
Xu, Ruiyong., Hong, Yanping., Shangguan, Xinchen., Yin, Zhongping., Jiang, Yan., Chen, Musen. Determination of total triterpene saponins in Cyclocarya paliurus (batal.) I1jinskaja by spectrophotometry. Jiangxi nongye daxue xuebao, 2007, p. 449-453.
Shu, RG., Xu, CR., Li, LN., Yu, ZL. Cyclocariosides II and III: Two secodammarane triterpenoid saponins from Cyclocarya paliurus. PLANTA MEDICA, 1995, vol. 61, no. 6, p. 551-553. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature