Botanical species · safety record

Cyclopia genistoides

The EFSA Compendium of Botanicals holds 1 constituent measurement and 2 adverse-effect records for Cyclopia genistoides. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Cyclopia genistoides (L.) Vent.

1Constituent measurements

2Safety records

3Cited sources

1Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 1 licensed products naming Cyclopia genistoides as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Benzophenone derivatives	Shoot	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Endocrine	—	Aerial part of plants	Solvent extraction	—	Not reported	Resolve DOI
Digestive	Digestive	Shoot	Solvent extraction	—	In vitro	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Beelders, Theresa., de Beer, Dalene., Stander, Maria A., Joubert, Elizabeth. Comprehensive Phenolic Profiling of Cyclopia genistoides (L.) Vent. by LC-DAD-MS and -MS/MS Reveals Novel Xanthone and Benzophenone Constituents. MOLECULES, 2014, vol. 19, no. 8, p. 11760-11790. DOI
de Beer, Dalene., Joubert, Elizabeth. Development of HPLC method for Cyclopia subternata phenolic compound analysis and application to other Cyclopia spp. . Journal of food composition and analysis, 2010, vol. 23, no. 3, p. 289-297. DOI
Beelders, Theresa., Brand, D. Jacobus., de Beer, Dalene., Malherbe, Christiaan J., Mazibuko, Sithandiwe E., Muller, Christo J. F., Joubert, Elizabeth. Benzophenone C- and O-Glucosides from Cyclopia genistoides (Honeybush) Inhibit Mammalian alpha-Glucosidase. Journal of Natural Products, 2014, p. 2694-2699.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature