Botanical species · safety record

Cynanchum atratum

The EFSA Compendium of Botanicals holds 7 constituent measurements for Cynanchum atratum. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Cynanchum atratum Bunge

7Constituent measurements

0Safety records

7Cited sources

7Licensed products (Canada)

Also recorded as

Vincetoxicum atratum (Bunge) C. Morren & Decne. ex Decne.

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 7 licensed products naming Cynanchum atratum as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Source material stated

Rhizome
Rhizome and root(s)
Root

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Pregnane derivatives	Roots and other underground parts	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Pregnane derivatives	Roots and other underground parts	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Pregnane derivatives	Roots and other underground parts	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	Resolve DOI
Pregnane derivatives	Live plants	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Pregnane derivatives	Roots and other underground parts	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Steroid derivatives	Roots and other underground parts	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Steroidal saponins	Roots and other underground parts	Solvent extraction	≤ 21.83 Milligram/gram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Bai, Hong., Li, Wei., Koike, Kazuo. Pregnane glycosides from Cynanchum atratum. Steroids, 2008, vol. 73, no. 1, p. 96-103. DOI
Yan, Ying., Zhang, Jian-xin., Liu, Kai-xing., Huang, Tao., Yan, Chen., Huang, Lie-jun., Liu, Sheng., Mu, Shu-zhen., Hao, Xiao-jiang. Seco-pregnane steroidal glycosides from the roots of Cynanchum atratum and their anti-TMV activity . Fitoterapia, 2014, vol. 97, p. 50-63. DOI
Bai, Hong., Li, Wei., Asada, Yoshihisa., Satou, Tadaaki., Wang, Yuanshu., Koike, Kazuo. Twelve pregnane glycosides from Cynanchum atratum. Steroids, 2009, vol. 74, no. 2, p. 198-207. DOI
Day, SH., Wang, JP., Won, SJ., Lin, CN. Bioactive constituents of the roots of Cynanchum atratum. Journal of natural products, 2001, vol. 64, no. 5, p. 608-611. DOI
Lee, KY., Sung, SH., Kim, YC. New acetylcholinesterase-inhibitory pregnane glycosides of Cynanchum atratum roots . Helvetica chimica acta, 2003, vol. 86, no. 2, p. 474-483. DOI
Liang, Mingjin., Zheng, Zhaoguang., Yuan, Ying., Kong, Lingyi., Shen, Yunheng., Liu, Runhui., Zhang, Chuan., Zhang, Weidong. Identification and quantification of C-21 steroidal saponins from radix cynanchi atrati by high-performance liquid chromatography with evaporation light scattering detection and electrospray mass spectrometric detection. PHYTOCHEMICAL ANALYSIS, 2007, vol. 18, no. 5, p. 428-435. DOI
Zhang, Zhi-Jun., Ding, Mei-Ling., Tao, Li-Jun., Zhang, Mian., Xu, Xiang-Hong., Zhang, Chao-Feng. Immunosuppressive C-21 steroidal glycosides from the root of Cynanchum atratum . Fitoterapia, 2015, vol. 105, p. 194-201. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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