Botanical species · safety record
Cynanchum viminale
The EFSA Compendium of Botanicals holds 8 constituent measurements and 8 adverse-effect records for Cynanchum viminale. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Cynanchum viminale (L.) L.
Also recorded as
Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.
Regulatory presence
No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.
What the records describe
Constituents measured
- Cardenolides1
- Indole1
- Pinoresinol1
- Pregnane derivatives1
- Saponins1
- Sarcovimiside b1
- Sarcovimisides1
- Tannins1
Plant parts
- Live plants13
- Aerial part of plants1
- Flower1
- Stem1
- stalk1
Preparations
- Solvent extraction7
- Drying (dehydration)6
- Fresh1
Effect types
- Neurotoxicity3
- Pulmonary and cardiac3
- Hepatotoxicity1
- Nephrotoxicity1
Target tissues
- Neurologic2
- Brain1
- Heart1
- Liver1
- Lung1
- Respiratory1
- Urogenital: kidneys1
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Saponins | Live plants | Solvent extraction | — | Phytochemical screening | Resolve DOI |
| Sarcovimiside b | Live plants | Solvent extraction | 5.26 Milligram/kilogram | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Sarcovimisides | Live plants | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Tannins | Live plants | Solvent extraction | — | Phytochemical screening | Resolve DOI |
| Cardenolides | Live plants | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | No resolvable identifier |
| Indole | Flower | Fresh | 14.3 Percent | — | No resolvable identifier |
| Pinoresinol | Aerial part of plants | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | No resolvable identifier |
| Pregnane derivatives | Stem / stalk | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | No resolvable identifier |
Recorded adverse effects
Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.
| Effect | Target tissue | Plant part | Preparation | Test organism | Test type | Source |
|---|---|---|---|---|---|---|
| Hepatotoxicity | Liver | Live plants | Drying (dehydration) | Bird (as animal) | Case report | Resolve DOI |
| Nephrotoxicity | Urogenital: kidneys | Live plants | Drying (dehydration) | Bird (as animal) | Case report | Resolve DOI |
| Neurotoxicity | Brain | Live plants | Drying (dehydration) | Bird (as animal) | Case report | Resolve DOI |
| Neurotoxicity | Neurologic | Live plants | — | Horse (as animal) | Case report | Resolve DOI |
| Neurotoxicity | Neurologic | Live plants | — | Ruminants (generic) (as animal) | Case report | Resolve DOI |
| Pulmonary and cardiac | Lung | Live plants | Drying (dehydration) | Bird (as animal) | Case report | Resolve DOI |
| Pulmonary and cardiac | Heart | Live plants | Drying (dehydration) | Bird (as animal) | Case report | Resolve DOI |
| Pulmonary and cardiac | Respiratory | Live plants | Drying (dehydration) | Bird (as animal) | Case report | Resolve DOI |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Cooper, Ross G. Poisoning in ostriches following ingestion of toxic plants - field observations. TROPICAL ANIMAL HEALTH AND PRODUCTION, 2007, vol. 39, no. 6, p. 439-442. DOI
- VLEGGAAR, R., VAN HEERDEN, FR., ANDERSON, LAP., ERASMUS, GL. TOXIC CONSTITUENTS OF THE ASCLEPIADACEAE - STRUCTURE ELUCIDATION OF SARCOVIMISIDE A-C, PREGNANE GLYCOSIDES OF SARCOSTEMMA-VIMINALE. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1993, no. 4, p. 483-487. DOI
- Botha, C. J., Penrith, M. -L. Poisonous plants of veterinary and human importance in southern Africa. JOURNAL OF ETHNOPHARMACOLOGY, 2008, vol. 119, no. 3, p. 549-558. DOI
- Steyn, Douw G. Recent investigations into the toxicity of known and unknown poisonous plants in the Union of South Africa. VII. Onderstepoort Journal of Veterinary Research, 1937, p. 111-124.
- Schaub, F., Kaufmann, H., Stoecklin, W., Reichstein, T. Glycosides and aglycons. CCCVII. Pregnane glycosides of the aerial parts of Sarcostemma viminale. Helvetica Chimica Acta, 1968, p. 738-767.
- Ahmad, Viqar Uddin., Zubair, Muhammad., Abbasi, Muhammad Athar., Kousar, Farzana., Nawaz, Sarfraz A., Choudhary, M. Iqbal., Hussaini, Syed Raziullah. Butyrylcholinesterase inhibitory lignans from Sarcostemma viminale. Proceedings of the Pakistan Academy of Sciences, 2005, p. 167-171.
- Schaub, F., Stoecklin, W., Reichstein, T. Glycosides and aglycons. CCCVIII. Structure of genins G (12-O-benzoyldeacetylmetaplexigenin) and H (di-O-benzoylviminolone) from Sarcostemma viminale stems. Helvetica Chimica Acta, 1968, p. 767-772.
- Girme, A.S., Bhalke, R.D., Nirmal, S.A., Chavan, M.J. Chromatographic and chemical analysis of Sarcostemma viminale R. Br.. Oriental pharmacy and experimental medicine, 2014, vol. 14, no. 3, p. 279-284. DOI
- Jurgens, Andreas., Dotterl, Stefan., Liede-Schumann, Sigrid., Meve, Ulrich. Chemical diversity of floral volatiles in Asclepiadoideae-Asclepiadeae (Apocynaceae). Biochemical Systematics and Ecology, 2008, p. 842-852.
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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