Botanical species · safety record

Cynanchum viminale

The EFSA Compendium of Botanicals holds 8 constituent measurements and 8 adverse-effect records for Cynanchum viminale. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Cynanchum viminale (L.) L.

8Constituent measurements
8Safety records
9Cited sources
0Licensed products (Canada)

Also recorded as

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

  • Cardenolides1
  • Indole1
  • Pinoresinol1
  • Pregnane derivatives1
  • Saponins1
  • Sarcovimiside b1
  • Sarcovimisides1
  • Tannins1

Plant parts

  • Live plants13
  • Aerial part of plants1
  • Flower1
  • Stem1
  • stalk1

Preparations

  • Solvent extraction7
  • Drying (dehydration)6
  • Fresh1

Effect types

  • Neurotoxicity3
  • Pulmonary and cardiac3
  • Hepatotoxicity1
  • Nephrotoxicity1

Target tissues

  • Neurologic2
  • Brain1
  • Heart1
  • Liver1
  • Lung1
  • Respiratory1
  • Urogenital: kidneys1

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
SaponinsLive plantsSolvent extractionPhytochemical screeningResolve DOI
Sarcovimiside bLive plantsSolvent extraction5.26 Milligram/kilogramNuclear Magnetic Resonance (NMR)Resolve DOI
SarcovimisidesLive plantsSolvent extractionNuclear Magnetic Resonance (NMR)Resolve DOI
TanninsLive plantsSolvent extractionPhytochemical screeningResolve DOI
CardenolidesLive plantsSolvent extractionNuclear Magnetic Resonance (NMR)No resolvable identifier
IndoleFlowerFresh14.3 PercentNo resolvable identifier
PinoresinolAerial part of plantsSolvent extractionNuclear Magnetic Resonance (NMR)No resolvable identifier
Pregnane derivativesStem / stalkSolvent extractionNuclear Magnetic Resonance (NMR)No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

EffectTarget tissuePlant partPreparationTest organismTest typeSource
HepatotoxicityLiverLive plantsDrying (dehydration)Bird (as animal)Case reportResolve DOI
NephrotoxicityUrogenital: kidneysLive plantsDrying (dehydration)Bird (as animal)Case reportResolve DOI
NeurotoxicityBrainLive plantsDrying (dehydration)Bird (as animal)Case reportResolve DOI
NeurotoxicityNeurologicLive plantsHorse (as animal)Case reportResolve DOI
NeurotoxicityNeurologicLive plantsRuminants (generic) (as animal)Case reportResolve DOI
Pulmonary and cardiacLungLive plantsDrying (dehydration)Bird (as animal)Case reportResolve DOI
Pulmonary and cardiacHeartLive plantsDrying (dehydration)Bird (as animal)Case reportResolve DOI
Pulmonary and cardiacRespiratoryLive plantsDrying (dehydration)Bird (as animal)Case reportResolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Cooper, Ross G. Poisoning in ostriches following ingestion of toxic plants - field observations. TROPICAL ANIMAL HEALTH AND PRODUCTION, 2007, vol. 39, no. 6, p. 439-442. DOI
  2. VLEGGAAR, R., VAN HEERDEN, FR., ANDERSON, LAP., ERASMUS, GL. TOXIC CONSTITUENTS OF THE ASCLEPIADACEAE - STRUCTURE ELUCIDATION OF SARCOVIMISIDE A-C, PREGNANE GLYCOSIDES OF SARCOSTEMMA-VIMINALE. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1993, no. 4, p. 483-487. DOI
  3. Botha, C. J., Penrith, M. -L. Poisonous plants of veterinary and human importance in southern Africa. JOURNAL OF ETHNOPHARMACOLOGY, 2008, vol. 119, no. 3, p. 549-558. DOI
  4. Steyn, Douw G. Recent investigations into the toxicity of known and unknown poisonous plants in the Union of South Africa. VII. Onderstepoort Journal of Veterinary Research, 1937, p. 111-124.
  5. Schaub, F., Kaufmann, H., Stoecklin, W., Reichstein, T. Glycosides and aglycons. CCCVII. Pregnane glycosides of the aerial parts of Sarcostemma viminale. Helvetica Chimica Acta, 1968, p. 738-767.
  6. Ahmad, Viqar Uddin., Zubair, Muhammad., Abbasi, Muhammad Athar., Kousar, Farzana., Nawaz, Sarfraz A., Choudhary, M. Iqbal., Hussaini, Syed Raziullah. Butyrylcholinesterase inhibitory lignans from Sarcostemma viminale. Proceedings of the Pakistan Academy of Sciences, 2005, p. 167-171.
  7. Schaub, F., Stoecklin, W., Reichstein, T. Glycosides and aglycons. CCCVIII. Structure of genins G (12-O-benzoyldeacetylmetaplexigenin) and H (di-O-benzoylviminolone) from Sarcostemma viminale stems. Helvetica Chimica Acta, 1968, p. 767-772.
  8. Girme, A.S., Bhalke, R.D., Nirmal, S.A., Chavan, M.J. Chromatographic and chemical analysis of Sarcostemma viminale R. Br.. Oriental pharmacy and experimental medicine, 2014, vol. 14, no. 3, p. 279-284. DOI
  9. Jurgens, Andreas., Dotterl, Stefan., Liede-Schumann, Sigrid., Meve, Ulrich. Chemical diversity of floral volatiles in Asclepiadoideae-Asclepiadeae (Apocynaceae). Biochemical Systematics and Ecology, 2008, p. 842-852.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

Continue