Botanical species · safety record

Daphne laureola

The EFSA Compendium of Botanicals holds 8 constituent measurements and 1 adverse-effect record for Daphne laureola. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Daphne laureola L.

8Constituent measurements

1Safety records

4Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Coumarin glycosides	Leaves	Solvent extraction	≥ 12153 ppm	HPLC-DAD	Resolve DOI
Coumarin glycosides	Leaves	Solvent extraction	≤ 23727 ppm	HPLC-DAD	Resolve DOI
Coumarin glycosides	Leaves	Solvent extraction	≥ 6221 ppm	HPLC-DAD	Resolve DOI
Coumarin glycosides	Leaves	Solvent extraction	≤ 14585 ppm	HPLC-DAD	Resolve DOI
Coumarin glycosides	Leaves	Solvent extraction	—	—	Resolve DOI
Coumarin glycosides	Leaves	Solvent extraction	≥ 37292 ppm	HPLC-DAD	Resolve DOI
Coumarin glycosides	Leaves	Solvent extraction	≤ 72584 ppm	HPLC-DAD	Resolve DOI
Violaxanthin	Bud	Solvent extraction	45 Millimole	Unspecified	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Nephrotoxicity	Urogenital: kidneys	Fruit unspecified	Raw, no heat treatment	Human (as organism)	Acute toxicity	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Fourast�, I. Reminder on the toxicity of some plants Rappel de la toxicit� de quelques plantes . Actualites pharmaceutiques, 2004, no. 432, p. 16-19.
Alonso, C., Perez, R., Nieto, PM., Delgado, J. Gender dimorphism and altitudinal variation of secondary compounds in leaves of the gynodioecious shrub Daphne laureola . Journal of chemical ecology, 2005, vol. 31, no. 1, p. 139-150. DOI
Garcia-Plazaola, Jose I., Hormaetxe, Koldobika., Hernandez, Antonio., Olano, Jose M., Becerril, Jose M. The lutein epoxide cycle in vegetative buds of woody plants. Functional plant biology, 2004, vol. 31, no. 8, p. 815-823.
Alonso, Conchita., Garcia, Isabel M., Zapata, Nelson., Perez, Ricardo. Variability in the behavioural responses of three generalist herbivores to the most abundant coumarin in Daphne laureola leaves . Entomologia experimentalis et applicata, 2009, vol. 132, no. 1, p. 76-83. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature