Botanical species · safety record

Davilla rugosa

The EFSA Compendium of Botanicals holds 9 constituent measurements and 4 adverse-effect records for Davilla rugosa. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Davilla rugosa Poir.

9Constituent measurements

4Safety records

4Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Alkaloids	Aerial part of plants	Solvent extraction	—	Phytochemical screening	Resolve DOI
Coumarins	Aerial part of plants	Solvent extraction	—	Phytochemical screening	Resolve DOI
Lignans	Aerial part of plants	Solvent extraction	—	Phytochemical screening	Resolve DOI
Saponins	Stem / stalk	Solvent extraction	—	—	Resolve DOI
Saponins	Aerial part of plants	Solvent extraction	—	Phytochemical screening	Resolve DOI
Saponins	Stem / stalk	Solvent extraction	—	Phytochemical screening	Resolve DOI
Tannins	Aerial part of plants	Solvent extraction	—	Phytochemical screening	Resolve DOI
Tannins	Aerial part of plants	Solvent extraction	≥ 10 Percent	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Tannins	Aerial part of plants	Solvent extraction	≤ 16.73 Percent	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Hepatotoxicity	Liver	Stem / stalk	Solvent extraction	Rat (as animal)	Short-term toxicity	Resolve DOI
Neurotoxicity	Neurologic	Stem / stalk	Solvent extraction	Rat (as animal)	Acute toxicity	Resolve DOI
Neurotoxicity	Neurologic	Stem / stalk	Solvent extraction	Rat (as animal)	Acute toxicity	Resolve DOI
Not stated	Neurologic	Aerial part of plants	Solvent extraction	House mouse (as animal)	Acute toxicity	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Mendes, Fulvio Rieli., Tabach, Ricardo., Carlini, E. A. Evaluation of Baccharis trimera and Davilla rugosa in tests for adaptogen activity. PHYTOTHERAPY RESEARCH, 2007, vol. 21, no. 6, p. 517-522. DOI
Guaraldo, L., Chagas, DA., Konno, AC., Korn, GP., Pfiffer, T., Nasello, AG. Hydroalcoholic extract and fractions of Davilla rugosa Poiret: effects on spontaneous motor activity and elevated plus-maze behavior. JOURNAL OF ETHNOPHARMACOLOGY, 2000, vol. 72, no. 1-2, p. 61-67. DOI
Guaraldo, L., Sertie, JAA., Bacchi, EM. Antiulcer action of the hydroalcoholic extract and fractions of Davilla rugosa Poiret in the rat. JOURNAL OF ETHNOPHARMACOLOGY, 2001, vol. 76, no. 2, p. 191-195. DOI
Macedo, Jessica Marques., Pellucci Souza, Luciana Godoy., Troncozo Valenzuela, Virgina del Carmem., Oliveira, Alaide Braga., Castilho, Rachel Oliveira., Ribeiro Paiva Jacome, Rose Lisieux. Seasonal variation in the flavonoid and tannin contents and antioxidant activity of Davilla rugosa Poir. Revista de Ciencias Farmaceuticas Basica e Aplicada, 2013, vol. 34, no. 4, p. 585-590.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature