Botanical species · safety record

Dermatophyllum secundiflorum

The EFSA Compendium of Botanicals holds 41 constituent measurements and 3 adverse-effect records for Dermatophyllum secundiflorum. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Dermatophyllum secundiflorum (Ortega) Gandhi & Reveal

41Constituent measurements

3Safety records

13Cited sources

0Licensed products (Canada)

Also recorded as

Sophora secundiflora (Ortega) Lag. ex DC.
Calia secundiflora (Ortega) Yakovlev

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
(-)-sparteine	Aerial part of plants	Solvent extraction	≤ 0.33 Percent	GC-FID	Resolve DOI
(-)-sparteine	Fruit unspecified	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
(-)-sparteine	Aerial part of plants	Solvent extraction	≥ 0.0087 Percent	GC-FID	Resolve DOI
Alkaloids	Fruit unspecified	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Anagyrine	Aerial part of plants	Solvent extraction	≥ 0.14 Percent	GC-FID	Resolve DOI
Anagyrine	Aerial part of plants	Solvent extraction	≤ 0.29 Percent	GC-FID	Resolve DOI
Biochanin-a	Stem / stalk	Solvent extraction	3 Milligram	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Calycosin	Roots and other underground parts	Solvent extraction	120 Milligram	—	Resolve DOI
Calycosin	Roots and other underground parts	Solvent extraction	234 Milligram	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Cytisine	Aerial part of plants	Solvent extraction	≥ 0.067 Percent	GC-FID	Resolve DOI
Cytisine	Aerial part of plants	Solvent extraction	≤ 0.92 Percent	GC-FID	Resolve DOI
Formononetin	Stem / stalk	Solvent extraction	52 Milligram	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Formononetin	Roots and other underground parts	Solvent extraction	142 Milligram	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Formononetin	Roots and other underground parts	Solvent extraction	6 Milligram	—	Resolve DOI
Genistein	Stem / stalk	Solvent extraction	9 Milligram	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Genistein	Roots and other underground parts	Solvent extraction	4 Milligram	—	Resolve DOI
Isosparteine	Fruit unspecified	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Lupanine	Aerial part of plants	Solvent extraction	≤ 0.028 Percent	GC-FID	Resolve DOI
Lupanine	Aerial part of plants	Solvent extraction	≥ 0.01 Percent	GC-FID	Resolve DOI
Lupanine	Fruit unspecified	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
N-methylcytisine	Fruit unspecified	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
N-methylcytisine	Aerial part of plants	Solvent extraction	≤ 0.12 Percent	GC-FID	Resolve DOI
N-methylcytisine	Aerial part of plants	Solvent extraction	≥ 0.0098 Percent	GC-FID	Resolve DOI
Pipecolic acid (-)-	Seed	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Pratensein	Roots and other underground parts	Solvent extraction	9 Milligram	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Prunetin	Stem / stalk	Solvent extraction	5 Milligram	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Quinolizidine alkaloids	Leaves	Solvent extraction	—	GC-MS	Resolve DOI
Quinolizidine alkaloids	Stem / stalk	Solvent extraction	—	GC-MS	Resolve DOI
(-)-sparteine	Leaves	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
(-)-sparteine	Seed	—	—	—	No resolvable identifier
Alkaloids	Leaves	Solvent extraction	9 Milligram	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Anagyrine	Seed	—	—	—	No resolvable identifier
Baptifoline	Leaves	Solvent extraction	5 Milligram	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Cytisine	Unspecified	—	—	—	No resolvable identifier
Cytisine	Leaves	Solvent extraction	2 Gram	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Lupanine	Seed	—	—	—	No resolvable identifier
Lupinine	Leaves	Solvent extraction	1.2 Gram	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
N-methylcytisine	Seed	—	—	—	No resolvable identifier
N-methylcytisine	Leaves	Solvent extraction	60 Milligram	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Quinolizidine alkaloids	Leaves	Solvent extraction	600 Milligram	Nuclear Magnetic Resonance (NMR)	No resolvable identifier

40 of 41 records are shown, ordered so that records carrying a resolvable reference come first.

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Neurotoxicity	Neurologic	Seed	—	Human (as organism)	Not reported	Resolve DOI
Digestive	Digestive	Seed	—	Human (as organism)	Case report	No resolvable identifier
Neurotoxicity	Brain	—	—	Human (as organism)	Case report	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Lee, Stephen T., Cook, Daniel., Molyneux, Russell J., Davis, T. Zane., Gardner, Dale R. Alkaloid profiles of Dermatophyllum arizonicum, Dermatophyllum gypsophilum, Dermatophyllum secundiflorum, Styphnolobium affine, and Styphnolobium japonicum previously classified as Sophora species. Biochemical systematics and ecology, 2013, vol. 49, p. 87-93. DOI
Abdel-Baky, A. M., Makboul, M. A. Sparteine and 13-hydroxy sparteine from leaves of Sophora secundiflora (Orteg.)Lag. Bulletin of pharmaceutical sciences, assiut university, 1985, vol. 8, no. 1, p. 99-108.
Kite, GC., Pennington, RT. Quinolizidine alkaloid status of Styphnolobium and Cladrastis (Leguminosae). Biochemical systematics and ecology, 2003, vol. 31, no. 12, p. 1409-1416. DOI
CHAVEZ, PI., SULLIVAN, G. A QUALITATIVE AND QUANTITATIVE COMPARISON OF THE QUINOLIZIDINE ALKALOIDS OF THE FASCIATED AND NORMAL STEMS OF SOPHORA-SECUNDIFLORA. Journal of natural products, 1984, vol. 47, no. 4, p. 735-736. DOI
Makboul, A. M., Abdel-Baky, A. M., Bishay, D. W. Argentine, lupinine, cytisine and N-methylcytisine alkaloids from Sophora secundiflora cultivated in Egypt. Bulletin of pharmaceutical sciences, assiut university, 1987, vol. 10, no. 2, p. 47-54.
Tanaka, T., Ohyama, M., Iinuma, M., Shirataki, Y., Komatsu, M., Burandt, CL. Isoflavonoids from Sophora secundiflora, S-arizonica and S-gypsophila. Phytochemistry, 1998, vol. 48, no. 7, p. 1187-1193. DOI
Shirataki, Y., Yoshida, S., Sugita, Y., Yokoe, I., Komatsu, M., Ohyama, M., Tanaka, T., Iinuma, M. Isoflavanones in roots of Sophora secundiflora. Phytochemistry, 1997, vol. 44, no. 4, p. 715-718. DOI
IZADDOOST, M., HARRIS, BG., GRACY, RW. STRUCTURE AND TOXICITY OF ALKALOIDS AND AMINO-ACIDS OF SOPHORA-SECUNDIFLORA. Journal of pharmaceutical sciences, 1976, vol. 65, no. 3, p. 352-354. DOI
KELLER, WJ., HATFIELD, M. 11-ALLYLCYTISINE AND OTHER MINOR ALKALOIDS FROM UNRIPE SOPHORA-SECUNDIFLORA FRUITS. Phytochemistry, 1979, vol. 18, no. 12, p. 2068-2069. DOI
Murakoshi, Isamu., Kubo, Hajime., Ikram, Mohammad., Israr, Mohammad., Shafi, Nusrat., Ohmiya, Shigeru., Otomasu, Hirotaka. (+)-11-Oxocytisine, a lupine alkaloid from leaves of Sophora secundiflora. Phytochemistry, 1986, vol. 25, no. 8, p. 2000-2.
STEGER, RE. NATIVE PLANTS POISONOUS TO HUMANS. Journal of range management, 1972, vol. 25, no. 1, p. 71-&. DOI
Roth, Brett., Domanski, Kristina. Sophora secundiflora ingestions reported to poison centers. Clinical toxicology, 2017, vol. 55, no. 7, p. 747-747.
IINUMA, M., OHYAMA, M., TANAKA, T., SHIRATAKI, Y., BURANDT, CL. ISOFLAVONOIDS IN ROOTS OF SOPHORA-SECUNDIFLORA. Phytochemistry, 1995, vol. 39, no. 4, p. 907-910. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature