Botanical species · safety record

Derris elliptica

The EFSA Compendium of Botanicals holds 15 constituent measurements and 6 adverse-effect records for Derris elliptica. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Derris elliptica (Wall.) Benth.

15Constituent measurements

6Safety records

7Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Isoflavones	Roots and other underground parts	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Rotenoids	Roots and other underground parts	Solvent extraction	—	HPLC with standard detection methods	Resolve DOI
Rotenone	Roots and other underground parts	Solvent extraction	9.6 Percent	Unspecified	Resolve DOI
Deguelin	Unspecified	—	—	HPLC with standard detection methods	No resolvable identifier
Rotenoids	Roots and other underground parts	Solvent extraction	≤ 0.015 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Rotenoids	Roots and other underground parts	Solvent extraction	≥ 0.013 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Rotenoids	Roots and other underground parts	Solvent extraction	≤ 20.74 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Rotenoids	Roots and other underground parts	Solvent extraction	≥ 20.66 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Rotenone	Roots and other underground parts	Solvent extraction	≥ 1.5 Percent	Phytochemical screening	No resolvable identifier
Rotenone	Roots and other underground parts	Solvent extraction	≤ 6 Percent	Phytochemical screening	No resolvable identifier
Rotenone	Roots and other underground parts	Solvent extraction	≤ 1.42 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Rotenone	Unspecified	—	—	HPLC with standard detection methods	No resolvable identifier
Rotenone	Roots and other underground parts	Solvent extraction	≥ 1.38 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Rotenone	Roots and other underground parts	Solvent extraction	≤ 7 Percent	Traditional analytical techniques (wet chemical tests)	No resolvable identifier
Rotenone	Roots and other underground parts	Solvent extraction	≥ 4.1 Percent	Traditional analytical techniques (wet chemical tests)	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Hepatotoxicity	Liver	Roots and other underground parts	—	Dog (as animal)	Subchronic	Resolve DOI
Hepatotoxicity	Liver	Roots and other underground parts	—	Rat (as animal)	Subchronic	Resolve DOI
Nephrotoxicity	Urogenital: kidneys	Roots and other underground parts	—	Rat (as animal)	Subchronic	Resolve DOI
Systemic	Digestive	Roots and other underground parts	—	Rat (as animal)	Subchronic	Resolve DOI
Systemic	Digestive	Roots and other underground parts	—	Dog (as animal)	Subchronic	Resolve DOI
Systemic	Digestive	Roots and other underground parts	—	Rabbit (as animal)	Short-term toxicity	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Takei, Sankichi. The constituents of Derris root. I. Rikagaku kenkyusho iho, 1923, vol. 2, p. 485-96.
Zubairi, S.I., Sarmidi, M.R., Aziz, R.A. Bio-active constituents of rotenoids resin extracted from Derris elliptica roots: Comparison between local plant extract and SAPHYR (France) cube resin. Advances in environmental biology, 2014, vol. 8, no. 4, p. 904-909.
Asib, Norhayu., Omar, Dzolkhifli., Awang, Rita Muhamad., Abdullah, Nur Ashikin Psyquay. Preparation, characterization and toxicity of nano-emulsion formulations of rotenone extract of Derris elliptica. Journal of chemical, biological and physical sciences, 2015, vol. 5, no. 4, p. 3989-3997.
Ambrose, A.M., Haag, H.B. Toxicological Studies o� Derris: Chronic Toxicity of Derris. Industrial and engineering chemistry, 1938, vol. 30, no. 5, p. 592-595. DOI
Pagan, C., Hageman, R. H. The effect of root diameter on chemical and biotoxic constituents of derris. Journal of agricultural research (washington, d. c.), 1949, vol. 78, p. 417-23.
Lu Hai-Ying., Liang Jing-Yu., Yu Ping., Chen Xue-Ying. Rotenoids from the Root of Derris elliptica (Roxb.) Benth. II. Chinese journal of natural medicines, 2009, vol. 7, no. 1, p. 24-26. DOI
Lu Hai-Ying., Liang Jing-Yu., Yu Ping., Qu Wei., Zhao Ling. Isoflavones and their derivatives from the root of Derris elliptica (Roxb.) Benth. . Chinese journal of natural medicines, 2008, vol. 6, no. 4, p. 265-267. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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