Botanical species · safety record
Descurainia sophia
The EFSA Compendium of Botanicals holds 11 constituent measurements and 1 adverse-effect record for Descurainia sophia. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Descurainia sophia (L.) Webb ex Prantl
Regulatory presence
Health Canada's Licensed Natural Health Products Database holds 29 licensed products naming Descurainia sophia as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.
Extract types on licence
Source material stated
What the records describe
Constituents measured
- 1,8-cineole1
- Alpha-cedrol1
- Bergapten1
- Isoscopoletin1
- Isothiocyanates1
- Methoxsalen1
- Psoralen1
- Scopoletin1
- Scopolin1
- Tagetone1
Plant parts
- Aerial part of plants7
- Flowering top3
- Seed1
- Unspecified1
Preparations
- Solvent extraction7
- Essential oil4
Effect types
- Digestive1
Target tissues
- Digestive1
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| 1,8-cineole | Flowering top | Essential oil | 2.58 Percent | GC-MS | Resolve DOI |
| Alpha-cedrol | Flowering top | Essential oil | 1.43 Percent | GC-MS | Resolve DOI |
| Tagetone | Flowering top | Essential oil | 1.04 Percent | GC-MS | Resolve DOI |
| Bergapten | Aerial part of plants | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | No resolvable identifier |
| Isoscopoletin | Aerial part of plants | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | No resolvable identifier |
| Isothiocyanates | Seed | Essential oil | — | GC-MS | No resolvable identifier |
| Methoxsalen | Aerial part of plants | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | No resolvable identifier |
| Psoralen | Aerial part of plants | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | No resolvable identifier |
| Scopoletin | Aerial part of plants | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | No resolvable identifier |
| Scopolin | Aerial part of plants | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | No resolvable identifier |
| Xanthotoxol | Aerial part of plants | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | No resolvable identifier |
Recorded adverse effects
Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.
| Effect | Target tissue | Plant part | Preparation | Test organism | Test type | Source |
|---|---|---|---|---|---|---|
| Digestive | Digestive | Unspecified | — | — | In vitro | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Mohamed, Nawal H., Mahrous, Atta E. Chemical Constituents of Descurainia sophia L. and its Biological Activity . Records of natural products, 2009, vol. 3, no. 1, p. 58-67.
- Li, Jing., Liu, Xingang., Dong, Fengshou., Xu, Jun., Zheng, Yongquan., Shan, Weili. Determination of the Volatile Composition in Essential Oil of Descurainia sophia (L.) Webb ex Prantl (Flixweed) by Gas Chromatography/Mass Spectrometry (GC/MS) . Molecules, 2010, vol. 15, no. 1, p. 233-240. DOI
- Khodarahmi, E., Asghari, G. H., Hassanzadeh, F., Mirian, M., Khodarahmi, G. A. Cytotoxic evaluation of volatile oil from Descurainia sophia seeds on MCF-7 and HeLa cell lines . Research in pharmaceutical sciences, 2015, vol. 10, no. 2, p. 169-176.
- Zarei, Mohammad., Poursharifi, Mina. Searching for alpha-glucosidase inhibitory activity in hexane extracts by some plants from Kurdistan province. International journal of advanced biological and biomedical research, 2015, vol. 3, no. 3, p. 291-296.
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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