Botanical species · safety record

Desmodium adscendens

The EFSA Compendium of Botanicals holds 10 constituent measurements and 4 adverse-effect records for Desmodium adscendens. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Desmodium adscendens (Sw.) DC.

10Constituent measurements
4Safety records
7Cited sources
6Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 6 licensed products naming Desmodium adscendens as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

  • Dry

Source material stated

  • Grass(es)
  • Herb
  • Leaf
  • Plante entière

What the records describe

Constituents measured

  • P-coumaric acid2
  • Triterpene saponins2
  • Alkaloids1
  • Gallic acid1
  • Hordenine1
  • Salsoline1
  • Saponins1
  • Tyramine1

Plant parts

  • Leaves8
  • Aerial part of plants6

Preparations

  • Solvent extraction14

Effect types

  • Systemic4

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
AlkaloidsLeavesSolvent extractionMass Spectroscopy and hyphenated methods without chromatographyResolve DOI
HordenineLeavesSolvent extractionMass Spectroscopy and hyphenated methods without chromatographyResolve DOI
SalsolineLeavesSolvent extractionMass Spectroscopy and hyphenated methods without chromatographyResolve DOI
SaponinsLeavesSolvent extractionMass Spectroscopy and hyphenated methods without chromatographyResolve DOI
Triterpene saponinsLeavesSolvent extractionNuclear Magnetic Resonance (NMR)Resolve DOI
Triterpene saponinsAerial part of plantsSolvent extractionStandard Chromatographic tests (paper- thin layer- and column chromatography)Resolve DOI
TyramineAerial part of plantsSolvent extractionUnspecifiedResolve DOI
Gallic acidLeavesSolvent extraction0.14 Gram/litreColorimetry, Spectroscopy (Spectrometry) and PhotometryNo resolvable identifier
P-coumaric acidLeavesSolvent extractionNuclear Magnetic Resonance (NMR)No resolvable identifier
P-coumaric acidLeavesSolvent extraction0.09 Gram/litreColorimetry, Spectroscopy (Spectrometry) and PhotometryNo resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

EffectTarget tissuePlant partPreparationTest organismTest typeSource
SystemicAerial part of plantsSolvent extractionHouse mouse (as animal)Short-term toxicityResolve DOI
SystemicAerial part of plantsSolvent extractionHouse mouse (as animal)Short-term toxicityResolve DOI
SystemicAerial part of plantsSolvent extractionHouse mouse (as animal)Acute toxicityResolve DOI
SystemicAerial part of plantsSolvent extractionHouse mouse (as animal)Acute toxicityResolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Rammal, H., Soulimani, R. Immunoactive profile of aqueous extracts of Desmodium adscendens in mice. Journal of herbs, spices and medicinal plants, 2011, vol. 17, no. 2, p. 154-168. DOI
  2. Asante, Kojo Isaac., Amuzu, Nancy., Donkor, Augustine., Annan, Kofi. Screening of some Ghanaian medicinal plants for phenolic compounds and radical scavenging activities. Pharmacognosy journal, 2009, vol. 1, no. 3, p. 201-206.
  3. Baiocchi, Claudio., Medana, Claudio., Giancotti, Valeria., Aigotti, Riccardo., Dal Bello, Frederica., Massolino, Cristina., Gastaldi, Daniela., Grandi, Maurizio. Qualitative characterization of Desmodium adscendens constituents by high-performance liquid chromatography-diode array ultraviolet-electrospray ionization multistage mass spectrometry . European journal of mass spectrometry, 2013, vol. 19, no. 1, p. 1-15. DOI
  4. ADDY, ME., SCHWARTZMAN, ML. AN EXTRACT OF DESMODIUM ADSCENDENS ACTIVATES CYCLOOXYGENASE AND INCREASES PROSTAGLANDIN SYNTHESIS BY RAM SEMINAL-VESICLE MICROSOMES . Phytotherapy research, 1995, vol. 9, no. 4, p. 287-293. DOI
  5. MCMANUS, OB., HARRIS, GH., GIANGIACOMO, KM., FEIGENBAUM, P., REUBEN, JP., ADDY, ME., BURKA, JF., KACZOROWSKI, GJ., GARCIA, ML. AN ACTIVATOR OF CALCIUM-DEPENDENT POTASSIUM CHANNELS ISOLATED FROM A MEDICINAL HERB . Biochemistry, 1993, vol. 32, no. 24, p. 6128-6133. DOI
  6. Addy, M.E. Several chromatographically distinct fractions of desmodium adscendens inhibit smooth muscle contractions. Pharmaceutical biology, 1989, vol. 27, no. 2, p. 81-91. DOI
  7. Muanda, Francois N., Soulimani, Rachid., Dicko, Amadou. Study on biological activities and chemical composition of extracts from Desmodium adscendens leaves. Journal of natural products (gorakhpur, india), 2011, vol. 4, p. 100-107.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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