Botanical species · safety record
Desmodium adscendens
The EFSA Compendium of Botanicals holds 10 constituent measurements and 4 adverse-effect records for Desmodium adscendens. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Desmodium adscendens (Sw.) DC.
Regulatory presence
Health Canada's Licensed Natural Health Products Database holds 6 licensed products naming Desmodium adscendens as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.
Extract types on licence
Source material stated
What the records describe
Constituents measured
- P-coumaric acid2
- Triterpene saponins2
- Alkaloids1
- Gallic acid1
- Hordenine1
- Salsoline1
- Saponins1
- Tyramine1
Plant parts
- Leaves8
- Aerial part of plants6
Preparations
- Solvent extraction14
Effect types
- Systemic4
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Alkaloids | Leaves | Solvent extraction | — | Mass Spectroscopy and hyphenated methods without chromatography | Resolve DOI |
| Hordenine | Leaves | Solvent extraction | — | Mass Spectroscopy and hyphenated methods without chromatography | Resolve DOI |
| Salsoline | Leaves | Solvent extraction | — | Mass Spectroscopy and hyphenated methods without chromatography | Resolve DOI |
| Saponins | Leaves | Solvent extraction | — | Mass Spectroscopy and hyphenated methods without chromatography | Resolve DOI |
| Triterpene saponins | Leaves | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Triterpene saponins | Aerial part of plants | Solvent extraction | — | Standard Chromatographic tests (paper- thin layer- and column chromatography) | Resolve DOI |
| Tyramine | Aerial part of plants | Solvent extraction | — | Unspecified | Resolve DOI |
| Gallic acid | Leaves | Solvent extraction | 0.14 Gram/litre | Colorimetry, Spectroscopy (Spectrometry) and Photometry | No resolvable identifier |
| P-coumaric acid | Leaves | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | No resolvable identifier |
| P-coumaric acid | Leaves | Solvent extraction | 0.09 Gram/litre | Colorimetry, Spectroscopy (Spectrometry) and Photometry | No resolvable identifier |
Recorded adverse effects
Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.
| Effect | Target tissue | Plant part | Preparation | Test organism | Test type | Source |
|---|---|---|---|---|---|---|
| Systemic | — | Aerial part of plants | Solvent extraction | House mouse (as animal) | Short-term toxicity | Resolve DOI |
| Systemic | — | Aerial part of plants | Solvent extraction | House mouse (as animal) | Short-term toxicity | Resolve DOI |
| Systemic | — | Aerial part of plants | Solvent extraction | House mouse (as animal) | Acute toxicity | Resolve DOI |
| Systemic | — | Aerial part of plants | Solvent extraction | House mouse (as animal) | Acute toxicity | Resolve DOI |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Rammal, H., Soulimani, R. Immunoactive profile of aqueous extracts of Desmodium adscendens in mice. Journal of herbs, spices and medicinal plants, 2011, vol. 17, no. 2, p. 154-168. DOI
- Asante, Kojo Isaac., Amuzu, Nancy., Donkor, Augustine., Annan, Kofi. Screening of some Ghanaian medicinal plants for phenolic compounds and radical scavenging activities. Pharmacognosy journal, 2009, vol. 1, no. 3, p. 201-206.
- Baiocchi, Claudio., Medana, Claudio., Giancotti, Valeria., Aigotti, Riccardo., Dal Bello, Frederica., Massolino, Cristina., Gastaldi, Daniela., Grandi, Maurizio. Qualitative characterization of Desmodium adscendens constituents by high-performance liquid chromatography-diode array ultraviolet-electrospray ionization multistage mass spectrometry . European journal of mass spectrometry, 2013, vol. 19, no. 1, p. 1-15. DOI
- ADDY, ME., SCHWARTZMAN, ML. AN EXTRACT OF DESMODIUM ADSCENDENS ACTIVATES CYCLOOXYGENASE AND INCREASES PROSTAGLANDIN SYNTHESIS BY RAM SEMINAL-VESICLE MICROSOMES . Phytotherapy research, 1995, vol. 9, no. 4, p. 287-293. DOI
- MCMANUS, OB., HARRIS, GH., GIANGIACOMO, KM., FEIGENBAUM, P., REUBEN, JP., ADDY, ME., BURKA, JF., KACZOROWSKI, GJ., GARCIA, ML. AN ACTIVATOR OF CALCIUM-DEPENDENT POTASSIUM CHANNELS ISOLATED FROM A MEDICINAL HERB . Biochemistry, 1993, vol. 32, no. 24, p. 6128-6133. DOI
- Addy, M.E. Several chromatographically distinct fractions of desmodium adscendens inhibit smooth muscle contractions. Pharmaceutical biology, 1989, vol. 27, no. 2, p. 81-91. DOI
- Muanda, Francois N., Soulimani, Rachid., Dicko, Amadou. Study on biological activities and chemical composition of extracts from Desmodium adscendens leaves. Journal of natural products (gorakhpur, india), 2011, vol. 4, p. 100-107.
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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