Botanical species · safety record

Dioscorea bulbifera

The EFSA Compendium of Botanicals holds 8 constituent measurements and 4 adverse-effect records for Dioscorea bulbifera. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Dioscorea bulbifera L.

8Constituent measurements

4Safety records

5Cited sources

11Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 11 licensed products naming Dioscorea bulbifera as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Source material stated

Rhizome
Tuber

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Cyanogenic glycosides	Roots and other underground parts used as staple food	Solvent extraction	3.3 ppm	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Saponins	Live plants	Solvent extraction	82.04 Percent	Element spectroscopy	Resolve DOI
Alkaloids	Live plants	Solvent extraction	≥ 0.26 Percent	Unspecified	No resolvable identifier
Alkaloids	Live plants	Solvent extraction	≤ 0.98 Percent	Unspecified	No resolvable identifier
Oxalates	Live plants	Solvent extraction	≤ 2.46 Milligram/100 gram	Unspecified	No resolvable identifier
Oxalates	Live plants	Solvent extraction	≥ 0.69 Milligram/100 gram	Unspecified	No resolvable identifier
Saponins	Live plants	Solvent extraction	≤ 79.48 Milligram/100 gram	Unspecified	No resolvable identifier
Saponins	Live plants	Solvent extraction	≥ 24.44 Milligram/100 gram	Unspecified	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Hepatotoxicity	Liver	Roots and other underground parts	—	Rat (as animal)	Acute toxicity	Resolve DOI
Hepatotoxicity	Liver	Roots and other underground parts	—	Rat (as animal)	Acute toxicity	Resolve DOI
Hepatotoxicity	Liver	Roots and other underground parts	—	Rat (as animal)	Acute toxicity	Resolve DOI
Hepatotoxicity	Liver	Live plants	Solvent extraction	Rat (as animal)	Subchronic	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Ogbuagu, M. N. Nutritive and anti-nutritive composition of the wild (in-edible) species of Dioscorea bulbifera (potato yam) and Dioscorea dumetorum (bitter yam). Journal of food technology (faisalabad, pakistan), 2008, vol. 6, no. 5, p. 224-226.
Zhao, Dong-Sheng., Jiang, Li-Long., Fan, Ya-Xi., Wang, Ling-Li., Li, Zhuo-Qing., Shi, Wei., Li, Ping., Li, Hui-Jun. Investigation of Dioscorea bulbifera rhizome-induced hepatotoxicity in rats by a multi-sample integrated metabolomics approach. . Chemical research in toxicology, 2017. DOI
Yang, Fan., Liang, Yuqiong., Xu, Li., Ji, Leilei., Yao, Nan., Liu, Ruonan., Shi, Le., Liang, Tao. Exploration in the cascade working mechanisms of liver injury induced by total saponins extracted from Rhizoma Dioscorea bulbifera . Biomedicine & pharmacotherapy, 2016, vol. 83, p. 1048-1056. DOI
Wang, Junming., Liang, Qingning., Ji, Lili., Liu, Hai., Wang, Changhong., Wang, Zhengtao. Gender-related difference in liver injury induced by Dioscorea bulbifera L. rhizome in mice . Human & experimental toxicology, 2011, vol. 30, no. 9, p. 1333-1341. DOI
Bhandari, MR., Kawabata, J. Bitterness and toxicity in wild yam (Dioscorea spp.) tubers of nepal. Plant foods for human nutrition, 2005, vol. 60, no. 3, p. 129-135. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature