Botanical species · safety record

Dioscorea collettii

The EFSA Compendium of Botanicals holds 10 constituent measurements for Dioscorea collettii. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Dioscorea collettii Hook.f.

10Constituent measurements

0Safety records

8Cited sources

1Licensed products (Canada)

Also recorded as

Dioscorea hypoglauca Palib.

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 1 licensed products naming Dioscorea collettii as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Source material stated

Rhizome

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Hypoglaucin g	Roots and other underground parts	Solvent extraction	—	—	Resolve DOI
Hypoglaucin g	Roots and other underground parts	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Methylprotodioscin	Roots and other underground parts	—	—	Unspecified	Resolve DOI
Protodioscin	Roots and other underground parts	Solvent extraction	—	—	Resolve DOI
Steroidal saponins	Roots and other underground parts	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Steroidal saponins	Roots and other underground parts	—	—	Unspecified	Resolve DOI
Saponins	Unspecified	—	≥ 0.84 Percent	UV/VIS spectroscopy (photometry)	No resolvable identifier
Saponins	Unspecified	—	≤ 2.85 Percent	UV/VIS spectroscopy (photometry)	No resolvable identifier
Steroidal saponins	Roots and other underground parts	Solvent extraction	≤ 4 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Steroidal saponins	Roots and other underground parts	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Hu, K., Yao, XS., Dong, AJ., Kobayashi, H., Iwasaki, S., Jing, YK. A new pregnane glycoside from Dioscorea collettii var. hypoglauca. JOURNAL OF NATURAL PRODUCTS, 1999, vol. 62, no. 2, p. 299-301. DOI
Hu, K., Yao, XS. The cytotoxicity of protoneodioscin (NSC-698789), a furostanol saponin from the rhizomes of Dioscorea collettii var. hypoglauca, against human cancer cells in vitro . Phytomedicine, 2002, vol. 9, no. 6, p. 560-565. DOI
Guo Long., Zeng Su-Ling., Zhang Yu., Li Ping., Liu E-Hu. Comparative analysis of steroidal saponins in four Dioscoreae herbs by high performance liquid chromatography coupled with mass spectrometry. Journal of pharmaceutical and biomedical analysis, 2015, p. 91-98.
Minghe, Y., Yanyong, C. Steroidal Sapogenins in Dioscorea collettii.. Planta medica, 1983, vol. 49, no. 9, p. 38-42. DOI
Hu, K., Dong, AJ., Yao, XS., Kobayashi, H., Iwasaki, S. Antineoplastic steroidal saponins from rhizomes of Dioscorea collettii var. hypoglauca. ADVANCES IN PLANT GLYCOSIDES, CHEMISTRY AND BIOLOGY, 1999, vol. 6, p. 220-229.
Li, Shu-qing., Xiao, Xiao., Wang, Kun-feng., Wu, Ling-fang., Zhang, Lan-zhen. Method for determination of total saponins in Dioscorea hypoglauca from different areas. Zhongguo shiyan fangjixue zazhi, 2013, p. 118-120.
Hu, K., Ya, XS. The cytotoxicity of methyl protoneogracillin (NSC-698793) and gracillin (NSC-698787), two steroidal saponins from the rhizomes of Dioscorea collettii var. hypoglauca, against human cancer cells in vitro . Phytotherapy research, 2003, vol. 17, no. 6, p. 620-626. DOI
Hu, K., Yao, XS. The cytotoxicity of methyl protodioscin against human cancer cell lines in vitro . Cancer investigation, 2003, vol. 21, no. 3, p. 389-393. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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