Botanical species · safety record

Dioscorea hispida

The EFSA Compendium of Botanicals holds 3 constituent measurements and 3 adverse-effect records for Dioscorea hispida. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Dioscorea hispida Dennst.

3Constituent measurements

3Safety records

4Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Dioscin	Roots and other underground parts	Solvent extraction	—	UHPLC-MS-MS	No resolvable identifier
Dioscorine	Roots and other underground parts used as staple food	Solvent extraction	≤ 0.72 Percent	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Dioscorine	Roots and other underground parts used as staple food	Solvent extraction	≥ 0.66 Percent	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Irritation	Skin/subcutis	Roots and other underground parts used as staple food	—	Human (as organism)	Case report	Resolve DOI
Hepatotoxicity	Liver	Roots and other underground parts used as staple food	Solvent extraction	Rat (as animal)	Short-term toxicity	No resolvable identifier
Neurotoxicity	Neurologic: central nervous system	Roots and other underground parts used as staple food	—	—	Case report	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Pochanugool, C., Chaiyabutr, N., Sitprija, V. Natural toxins in Thailand. Journal of toxicology-toxin reviews, 1996, vol. 15, no. 1, p. 19-36.
Joob, B., Wiwanitkit, V. Asiatic bitter yam intoxication. Asian pacific journal of tropical biomedicine, 2014, vol. 4, p. S42. DOI
Faradianna Lokman, Ezarul., Muhammad, Hussin., Awang, Norizah., Hasyima Omar, Maizatul., Mansor, Fazliana., Saparuddin, Fatin. Gene Expression Profiling associated with Hepatoxicity in Pregnant Rats treated with Ubi Gadong (Dioscorea hispida) Extract. . International journal of biomedical science : ijbs, 2017, vol. 13, no. 1, p. 26-34.
Sasiwatpaisit, N., Thitikornpong, W., Palanuvej, C., Ruangrungsi, N. Dioscorine content in Dioscorea hispida dried tubers in Thailand by TLC-densitometry and TLC image analysis. Journal of chemical and pharmaceutical research, 2014, vol. 6, no. 4, p. 803-806.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature