Botanical species · safety record

Duboisia myoporoides

The EFSA Compendium of Botanicals holds 32 constituent measurements and 1 adverse-effect record for Duboisia myoporoides. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Duboisia myoporoides R.Br.

32Constituent measurements

1Safety records

10Cited sources

5Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 5 licensed products naming Duboisia myoporoides as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Source material stated

Leaf
Leaves

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Alkaloids	Leaves	Solvent extraction	≥ 2220 Microgram/square decimetre	Gaschromatography (GC)	Resolve DOI
Alkaloids	Leaves	Solvent extraction	≤ 8960 Microgram/square decimetre	Gaschromatography (GC)	Resolve DOI
Anabasine	Leaves	Solvent extraction	≥ 0.39 Percent	Chromatographic tests	Resolve DOI
Anabasine	Leaves	Solvent extraction	≤ 1.4 Percent	Chromatographic tests	Resolve DOI
Apoatropine	Leaves	Solvent extraction	—	Mass Spectroscopy and hyphenated methods without chromatography	Resolve DOI
Esculetin	Aerial part of plants	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Hyoscyamine	Leaves	Solvent extraction	≤ 3 Milligram/gram	UHPLC-MS-MS	Resolve DOI
Hyoscyamine	Leaves	Solvent extraction	≥ 2.5 Milligram/gram	UHPLC-MS-MS	Resolve DOI
Hyoscyamine	Leaves	Solvent extraction	≥ 80 Microgram/square decimetre	Gaschromatography (GC)	Resolve DOI
Hyoscyamine	Leaves	Solvent extraction	≤ 1590 Microgram/square decimetre	Gaschromatography (GC)	Resolve DOI
Hyoscyamine	Leaves	Solvent extraction	1.5 Milligram/gram	UHPLC-MS-MS	Resolve DOI
Nicotine	Leaves	Solvent extraction	≥ 0.06 Percent	Chromatographic tests	Resolve DOI
Nicotine	Leaves	Solvent extraction	≤ 0.3 Percent	Chromatographic tests	Resolve DOI
Pelletierine	Leaves	Solvent extraction	≥ 0.09 Percent	Chromatographic tests	Resolve DOI
Pelletierine	Leaves	Solvent extraction	≤ 0.25 Percent	Chromatographic tests	Resolve DOI
Scopolamine	Leaves	Solvent extraction	≥ 2000 Microgram/square decimetre	Gaschromatography (GC)	Resolve DOI
Scopolamine	Leaves	Solvent extraction	≤ 7400 Microgram/square decimetre	Gaschromatography (GC)	Resolve DOI
Scopolamine	Leaves	Solvent extraction	12.71 Milligram/gram	UHPLC-MS-MS	Resolve DOI
Scopoletin	Aerial part of plants	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Scopolin	Aerial part of plants	Solvent extraction	0.1 Milligram/gram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Tropane alkaloids	Unspecified	—	—	Unspecified	Resolve DOI
Tropane alkaloids	Leaves	Solvent extraction	—	Mass Spectroscopy and hyphenated methods without chromatography	Resolve DOI
Tropane alkaloids	Leaves	Solvent extraction	≤ 0.09 Percent	Chromatographic tests	Resolve DOI
Tropane alkaloids	Leaves	Solvent extraction	≥ 0.08 Percent	Chromatographic tests	Resolve DOI
Tropane alkaloids	Leaves	Solvent extraction	0.06 Microgram/gram	Chromatographic tests	Resolve DOI
Tropane alkaloids	Leaves	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Tropine	Leaves	Solvent extraction	—	Mass Spectroscopy and hyphenated methods without chromatography	Resolve DOI
Valtropine	Leaves	Solvent extraction	—	Mass Spectroscopy and hyphenated methods without chromatography	Resolve DOI
Anabasine	Shoot	Solvent extraction	0.56 Percent Area	Chromatographic tests	No resolvable identifier
Atropine	Shoot	Solvent extraction	0.25 Percent Area	Chromatographic tests	No resolvable identifier
Nicotine	Shoot	Solvent extraction	0.91 Percent Area	Chromatographic tests	No resolvable identifier
Scopolamine	Shoot	Solvent extraction	0.7 Percent Area	Chromatographic tests	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Systemic	—	Leaves	—	—	Case report	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Fliniaux, MA., GilletManceau, F., Marty, D., Macek, T., Monti, JP., JacquinDubreuil, A. Evaluation of the relation between the endogenous scopoletin and scopolin level of some solanaceous and papaver cell suspensions and their ability to bioconvert scopoletin to scopolin . Plant science, 1997, vol. 123, no. 1-2, p. 205-210. DOI
Foley, P. Duboisia myoporoides: The medical career of a native Australian plant. Historical records of australian science, 2006, vol. 17, no. 1, p. 31-69. DOI
SHUKLA, YN., THAKUR, RS. TROPANE ALKALOIDS FROM DUBOISIA-MYOPOROIDES. Phytochemistry, 1992, vol. 31, no. 12, p. 4389-4390. DOI
MORTIMER, PI., WILKINSON, S. THE OCCURRENCE OF NICOTINE, ANABASINE, AND ISOPELLETIERINE IN DUBOISIA-MYOPOROIDES . Journal of the chemical society, 1957, no. SEP, p. 3967-3970. DOI
Ullrich, Sophie Friederike., Averesch, Nils J. H., Castellanos, Leonardo., Choi, Young Hae., Rothauer, Andreas., Kayser, Oliver. Discrimination of wild types and hybrids of Duboisia myoporoides and Duboisia leichhardtii at different growth stages using H-1 NMR-based metabolite profiling and tropane alkaloids-targeted HPLC-MS analysis . Phytochemistry, 2016, vol. 131, p. 44-56. DOI
KITAMURA, Y., YAMASHITA, R., MIURA, H., WATANABE, M. PHLOEM TRANSPORT OF TROPANE AND PYRIDINE ALKALOIDS IN DUBOISIA-MYOPOROIDES . Journal of plant physiology, 1993, vol. 142, no. 5, p. 635-637.
Mishra, S., Sangwan, R.S. Dynamics of tropane alkaloids in Duboisia myoporoides leaf during development. Journal of herbs, spices and medicinal plants, 1996, vol. 4, no. 3, p. 61-70. DOI
Khanam, N., Khoo, C., Khan, AG. Effects of cytokinin-auxin combinations on cell arrangement in the basal stems and tropane alkaloid production in cultured non-rooted shoots of Duboisia myoporoides . Australian journal of botany, 2001, vol. 49, no. 4, p. 443-450. DOI
Pellowe, Elizabeth., Poncia, Hugo D. M. Duboisia ingestion: An unusual cause of anticholinergic poisoning. Emergency medicine australasia, 2013, vol. 25, no. 3, p. 268-270. DOI
Naumann, A., Kurtze, L., Kr�hmer, A., Hagels, H., Schulz, H. Discrimination of solanaceae taxa and quantification of scopolamine and hyoscyamine by ATR-FTIR spectroscopy. Planta medica, 2014, vol. 80, no. 15, p. 1315-1320. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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